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Kai Murk

@kaimurk

Cell & Neurobiologist. Group Leader & Lecturer at the Institute of Biochemistry, Charité Berlin. Research interest in the actin cytoskeleton and membrane trafficking in astrocytes.

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22.09.2023
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Latest posts by Kai Murk @kaimurk

Congratulations, Shashank! Well deserved.

21.02.2026 21:00 👍 1 🔁 0 💬 1 📌 0
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Newest advancement in German train technology: Stealth S-Bahn (Overground) train in Berlin. According to the @deutschebahn.com announcement, the train stands here ready for departure, but I cannot see it, although I am supposedly standing right in front of it...

19.02.2026 17:51 👍 0 🔁 0 💬 0 📌 0
Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab

Postdoc job alert in the Crick Institute in London. Are you interested in the actin cytoskeleton? I am looking for a postdoc to examine the cellular, developmental or physiological role of Arp2/3 iso-complex driven actin polymerisation. Multiple aspects available.
crick.ac.uk/WayPostdoc2026

06.02.2026 08:23 👍 26 🔁 29 💬 0 📌 4
Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab

2nd postdoc job alert in the Crick Institute in London. Project will examine the role of motors & the cytoskeleton (actin, septins and microtubules) during vaccinia virus egress using biochemical, structural & cellular approaches + live cell imaging. spread the word.
crick.ac.uk/WayPostdoc20...

06.02.2026 08:29 👍 30 🔁 40 💬 0 📌 1
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Postdocs wanted - Please spread the word! We are looking for one bioinformatician and 1-2 cell biologists with different expertise! See the job ad below for more information and links to the job descriptions!

20.01.2026 12:48 👍 26 🔁 26 💬 0 📌 2
FÖRDERENTSCHEIDUNGEN und TERMINE 2026
25.-26.03.  Senat / Hauptausschuss
27.03. neue / verlängerte Forschungsgruppen
27.03. neue Schwerpunktprogramme SPP
15.05. neue / verlängerte SFB
01.06. neue / verlängerte Graduiertenkollegs
29.06.-01.07.  DFG-Jahresversammlung in Bonn
29.-30.06. Senat / Hauptausschuss
01.07. neue / verlängerte Forschungsgruppen
01.07.  DFG-Jahresbericht 2025
16.-17.09.  Senat / Hauptausschuss
18.09. neue / verlängerte Forschungsgruppen
16.11. neue / verlängerte Graduiertenkollegs
26.11.	neue / verlängerte SFB
09.-10.12.  Senat / Hauptausschuss
10.12. Forschungsimpulse FIP
11.12.	neue / verlängerte Forschungsgruppen

FÖRDERENTSCHEIDUNGEN und TERMINE 2026 25.-26.03. Senat / Hauptausschuss 27.03. neue / verlängerte Forschungsgruppen 27.03. neue Schwerpunktprogramme SPP 15.05. neue / verlängerte SFB 01.06. neue / verlängerte Graduiertenkollegs 29.06.-01.07. DFG-Jahresversammlung in Bonn 29.-30.06. Senat / Hauptausschuss 01.07. neue / verlängerte Forschungsgruppen 01.07. DFG-Jahresbericht 2025 16.-17.09. Senat / Hauptausschuss 18.09. neue / verlängerte Forschungsgruppen 16.11. neue / verlängerte Graduiertenkollegs 26.11. neue / verlängerte SFB 09.-10.12. Senat / Hauptausschuss 10.12. Forschungsimpulse FIP 11.12. neue / verlängerte Forschungsgruppen

Termine! 📅 2026 tagen die DFG-Gremien turnusmäßig wieder 4 Mal – und beraten sich über Anträge in der Einzelförderung, von Forschungsgruppen und andere Entscheidungsvorlagen. Die Ausschüsse der Graduiertenkollegs (GRK) und Sonderforschungsbereichen (SFB) kommen an gesonderten Terminen zusammen.

15.01.2026 08:52 👍 20 🔁 9 💬 1 📌 0
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20-plex volumetric super-resolution imaging of cellular ultrastructure. Preprint, led by @seweryn-galecki.bsky.social, dropping soon.

01.01.2026 23:10 👍 38 🔁 7 💬 2 📌 1

In parallel, we'll be publishing a special issue on Imaging Cell Architecture and Dynamics - you can find out more at:
journals.biologists.com/jcs/pages/im...

Submission deadline: 1 April 2026

#imaging #microscopy #cellbiology

18.12.2025 14:47 👍 13 🔁 9 💬 1 📌 1
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The regulatory code of injury-responsive enhancers enables precision cell-state targeting in the CNS - Nature Neuroscience Zamboni et al. reveal how enhancers encode cell-type-specific responses to CNS injury. By combining multiomic profiling, deep learning and in vivo screening, they uncover injury-responsive enhancer lo...

Great study in @natneuro.nature.com revealing reactive astrocyte-specific enhancers by @margheritazamboni.bsky.social et al (@ellorens.bsky.social, @ki.se) + it brings along a neat AAV to target reactive astrocytes => definitely one tool that we want to try out www.nature.com/articles/s41...

09.12.2025 17:00 👍 3 🔁 0 💬 0 📌 0

Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.

04.12.2025 08:42 👍 34 🔁 33 💬 0 📌 1
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Introducing mScarlet3-S2: a highly photostable and bright red fluorescent protein.

www.nature.com/articles/s41...

04.12.2025 20:19 👍 25 🔁 7 💬 0 📌 0
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From aerospace to neuroscience: new imaging tech captures the brain’s intricate connections Inspired by technologies used in aerospace engineering, scientists have developed a way to capture the brain’s intricate structures using X-rays without destroying the samples.

Researchers at the Crick, @psich.bsky.social and @esrf.fr have developed a new way to look deeper into brain cell connections by using a particle accelerator and a kind of resin borrowed from the aerospace industry.
www.crick.ac.uk/news/2025-11...

27.11.2025 12:09 👍 22 🔁 10 💬 2 📌 0

Very cool indeed!

27.11.2025 13:50 👍 0 🔁 0 💬 0 📌 0
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Tomorrow we will celebrate the 10th Anniversary of our AMBIO Imaging Facility. I am very much to see a lot of cutting edge microscopy data.

18.11.2025 19:49 👍 1 🔁 0 💬 0 📌 0
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Check out our recent preprint, "Live longitudinal imaging of meningeal cerebrovascular injury and its sequelae in adult zebrafish."

lnkd.in/gN7z6th4

18.11.2025 02:42 👍 36 🔁 14 💬 0 📌 3
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Macrophages are super!
SoRA (superresolution after optical reassignment) microscopy video of a primary human macrophage transfected with Lifeact-GFP to visualize actin-rich podosomes.
Star-like appearance is due to connecting cables linking individual podosomes into a cell-wide superstructure ✨

07.11.2025 15:25 👍 3 🔁 1 💬 0 📌 0
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Secretome translation shaped by lysosomes and lunapark-marked ER junctions - Nature Live-cell imaging of mRNA encoding secretome proteins and translated nascent peptide markers show that secretome translation occurs at endoplasmic reticulum junctions near lysosomes, requires lun...

A fantastic paper by my @hhmijanelia.bsky.social colleague and friend Heejun Choi (who is on the job market!). Another elegant use of the Janelia Fluor dyes for cellular imaging. www.nature.com/articles/s41...

06.11.2025 14:24 👍 26 🔁 6 💬 0 📌 0
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What a gem from @dudinlab.bsky.social @gautamdey.bsky.social @centriolelab.bsky.social in Cell! Expansion microscopy atlas of >200 eukaryotes comparing cytoskeletal architectures revealing structures not seen before. Stunning visualisation! Exactly the kind of transformative cell biology we need.

31.10.2025 17:43 👍 137 🔁 55 💬 4 📌 1
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This study reflects the dedication of a great team over many years. I am sincerely thankful to my co-first author Tom Bickel, to our PI Christian Madry and to all collaborators who brought their expertise and care to this work.

Read the full story here: www.science.org/doi/10.1126/...

25.10.2025 15:21 👍 2 🔁 1 💬 0 📌 0
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Microglia are the brain’s most dynamic cells, constantly extending and retracting their processes to monitor the parenchyma and respond to potential danger with inflammatory signaling.

Our new study in @ScienceAdvances @science.org explores how these functions are regulated.

25.10.2025 15:21 👍 44 🔁 8 💬 2 📌 0

This is from one preparation from mouse cortex E16.5. Microglia and astrocytes are kind of rare at this stage but keep the act (culture) together.

23.10.2025 17:38 👍 0 🔁 0 💬 0 📌 0

Check out our exciting project on sex differences at the BBB

#sex_differences #astrocytes #depression
Funding: @fwf-at.bsky.social
In collaboration with @dibenedetto-lab.bsky.social

22.10.2025 19:35 👍 7 🔁 3 💬 0 📌 0
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The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation CLIC1 regulates surveillance, morphology, and interleukin release in mouse and human brain microglia.

Very interesting paper in Science Advances by the Madry lab showing that the chloride channel Clic1 regulates morphodynamics and surveillance of #microglia via ERM proteins. These functions are chloride independent. www.science.org/doi/10.1126/...

22.10.2025 19:37 👍 7 🔁 1 💬 0 📌 0
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#microscopymonday video on a multitalented housekeeper in the #brain: Watch amidst #neurons an #astrocyte. The astrocyte phagocytoses debris but is rather stationary compared to the bypassing #microglia cell. #Neurons thrive around the astrocyte and outgrow neurites.

19.10.2025 17:33 👍 6 🔁 1 💬 0 📌 0
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Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI

10.10.2025 14:24 👍 28 🔁 24 💬 1 📌 1

Total imaging duration was 48 hours.

12.10.2025 16:34 👍 0 🔁 0 💬 0 📌 0
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This #microscopymonday is a cleaning day. Watch how a #microglia cell mops up and phagozytoses debris and junk in a very messy neuronal co-culture. BTW, it was a proper cleaning job → the neurons made it and formed nice networks
Phase contrast imaging started at DIV1. One frame per 20 min.

12.10.2025 16:32 👍 24 🔁 8 💬 2 📌 0

Congratulations, Suze!

07.10.2025 17:03 👍 0 🔁 0 💬 0 📌 0
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Joint Professorship for Susanne Wegmann at DZNE and Charité Boost for Brain Research in Berlin.

🎉 Congratulations to Dr. Susanne Wegmann on her joint professorship at DZNE and Charité!
Her research focuses on the Tau protein in neurodegenerative diseases - a strong boost for brain research in Berlin!

👉 www.dzne.de/en/news/pres...

07.10.2025 10:24 👍 21 🔁 5 💬 1 📌 1
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Something for a belayed #FluorescentFriday. #actin dynamics in differentiating neuroblastoma cells. 'It's fascinating to observe the dynamics of #actin in growth cones and filopodia, even though it's merely GFP-actin.
CSU-W1 SoRa Spinning disk #microscopy performed at the AMBIO facility (Charité).

04.10.2025 09:09 👍 17 🔁 2 💬 0 📌 0