Miguel Reyes-Múgica, MD

A Master Class on Sleep Professor Yo-El Ju, With plenty of practical tips

The latest on sleep science and getting better quality sleep
erictopol.substack.com/p/a-master-c...

This week's cover @thelancet.com

We hope you find useful our new publication describing the changes in the GI6 volume of the WHO Blue Books. @IARCWHO #Pathology #GIPathology #PediPath Open access: doi.org/10.1111/his.... @UMiamiPathology tumourclassification.iarc.who.int/home

Progress!

Salma Hayek destroza a la derecha: "Me ha tocado y sentir el cambio" YouTube video by NoticiaMx

Disfruten esto. A mí me encantó: youtu.be/CAP9qyMy5mU?...

A 1933 self-portrait oil painting by Frida Kahlo, titled "Self-Portrait with Necklace." Frida is depicted from the chest up against a plain grey-blue background, wearing a simple white lace-trimmed blouse and a heavy necklace of large, dark round stones. She gazes directly forward with a serious expression, featuring her signature bold unibrow and a black ribbon tied in her hair.

After 20 years, the Gelman Santander Collection hits CDMX again, now at the MAM. From Kahlo’s soul to Rivera’s grit, it’s a raw, high-stakes look at our visual DNA. A masterclass in Mexican legacy, can’t wait!

When protein losing enteropathy persists: A case series of viral and lymphatic‐associated etiologies Protein-losing enteropathy (PLE) is a rare condition that is characterized by loss of plasma protein in the intestines leading to hypoproteinemia with subsequent peripheral edema and possibly anasarc...

Happy to share our new contribution to #PediPath. I hope you find it interesting: When protein losing enteropathy persists: A case series of viral and lymphatic‐associated etiologies - Jennings - JPGN Reports - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...

#TooCloseToDiagnose? 🧐
A. Clear Cell Acanthoma
B. Trichilemmoma
C. Bowen's Disease
D. Paget's Disease
#Pathology #Dermatology #Dermatopathology #DermPath

Black-and-white concert photo of Ray Charles singing and playing piano on stage, captured live in Paris in 1961, with dramatic lighting and a vintage jazz atmosphere.

And to think this record immortalizes a series of concerts that became the soundtrack of Paris, while outside the theaters the city was living through the October 1961 massacre of Algerians. Beauty and violence sharing the same moment in time.

#CytoQuiz #SoftTissue 🔬
A) Angiolipoma
B) Lipoma
C) Hibernoma
D) Myxoid Liposarcoma
#CytoPath #Pathology
🙏 🖼️ @CytoAtlas

Bulletin President and CEO Alexandra Bell reaches out to move the time on the Clock hand.

Science and Security Board members Jon Wolfsthal, Asha M. George, and Steve Fetter stand beside the Doomsday Clock as President and CEO Alexandra Bell delivers remarks.

Bulletin President and CEO Alexandra Bell gives remarks at a podium.

A close up of the Clock time shows its setting at 85 seconds to midnight.

The 2026 Doomsday Clock announcement, captured by photographer Jamie Christiani.

IT IS 85 SECONDS TO MIDNIGHT.

Watch the 2026 Doomsday Clock announcement: buff.ly/BGu0Zse

#alexpretti

Hay que mantenerse alerta y precavido. Mucha suerte. 🍀

😓

The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations - Nature Communications Asthma exacerbations remain hard to predict with routine tests. Here, the authors show that simple blood sphingolipid-to-steroid ratios predict five-year exacerbation risk and can underpin a practical...

Predicting asthma attacks up to 5 years in advance. Discovery and validation of a metabolite biomarker (sphingolipid-to-steroid ratio), via 3 large cohorts with up to 25 years of follow-up
nature.com/articles/s41...

GPS was a team goal. JHU/APL played midfield, shaping the physics and the field. And the one and only, Gladys West was the playmaker: her mathematics delivered the assist that made the goal possible. Science isn’t a solo act, it’s the result of every outstanding, independent participation.

It is a pleasure to share our new contribution to #PediPath describing melanocytes in the umbilical cord: doi.org/10.1016/j.pl...

Here's a summary of all the data that supports adding more red meat to your diet

Congratulations to the Lab of Won Jae Huh, MD, PhD, of @yaleschoolofmed.bsky.social. Their work graces the January cover of #TheJournalOfPathology, “Transcriptomic profiling reveals the role of Hedgehog signaling as a biomarker & in the pathogenesis of Ménétrier's disease.” bit.ly/4jrUnrE

Gut micro-organisms associated with health, nutrition and dietary interventions - Nature Comprehensive large-scale studies of multi-national populations identified microbiome species consistently associated with favourable and unfavourable health markers, informing future studies of the human gut microbiome and its association with diet and cardiometabolic conditions.

Nature research paper: Gut micro-organisms associated with health, nutrition and dietary interventions

go.nature.com/4oODWqv

I don’t use spotylie…

Why is your separase such a big protease? Recent structural work explains a fundamental event during cell division, the timely and specific cleavage of the chromosomal cohesin complex by the protease separase.

Great advance in science! Why is your separase such a big protease? | Science Advances www.science.org/doi/10.1126/...

For children and teens, heart and blood vessel complications of Covid overshadow the very rare and short-term risk of vaccinations, a new report from nearly 14 million kids
www.thelancet.com/journals/lan...

Chimpanzees rationally revise their beliefs The selective revision of beliefs in light of new evidence has been considered one of the hallmarks of human-level rationality. However, tests of this ability in other species are lacking. We examined...

Even chimpanzees think rationally and weigh the evidence when making a choice ;-)
@science.org
www.science.org/doi/10.1126/...

Step Accumulation Patterns and Risk for Cardiovascular Events and Mortality Among Suboptimally Active Adults | Annals of Internal Medicine Background: Although physical activity recommendations increasingly consider daily step counts, it remains unclear whether step accumulation patterns—short versus sustained longer bouts—affect associa...

Longer walks linked with less mortality and cardiovascular risk compared with short bouts of physical activity
@annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...

Amazing video and description of Ectopia Cordis in the
@NEJM
! I have seen and written about this rare congenital heart and thoracic malformation. nejm.org/doi/full/10.... Pediatric Pathology> 1 I :85-95, 1991 & American Journal of Medical Genetics 44540 (1992)
#PediPath

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions Pediatric cutaneous T-cell lymphoproliferative disorders encompass a diagnostically complex set of rare diseases of undefined pathogenesis, including mycosis fungoides (MF), lymphomatoid papulosis (Ly...

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions - Modern Pathology www.modernpathology.org/article/S089...

People with some cancers live longer after a COVID vaccine mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer ― in an unexpected way.

A vaccine that helps to fight cancer might already exist: People being treated for deadly cancers lived longer if they had received an mRNA COVID-19 vaccine.

The vaccines have this apparent life-extending effect not because they protect against COVID-19 but because they rev up the immune system.

In a cohort of over 13,500 women with mean age ~72 years, >4,000 steps per day, at least 1-2 days per week, was associated with reduction in all-cause mortality and lower risk of cardiovascular disease
bjsm.bmj.com/content/earl...

Peter Sellers was great!