Miranda Evans

🚨Open Access paper out today in Praehistorische Zeitschrift!

"A first toast in Kuyavia: New evidence for drinking rituals in Neolithic Europe from Sławęcinek, Poland"
Led by Łukasz Kowalski

www.degruyterbrill.com/document/doi...

Thank you!

Thank you!

5/5
🏺 This matters because alternate peptide sequences can lead to inaccurate protein taxonomy and archaeological interpretations. The Demodifier is fast and open source, enabling easy detection of MISPs.
📄 Paper: doi.org/10.1371/jour...
💻 GitHub: github.com/miranda-e/De...

4/5
📊 The Demodifier was applied to a test dataset including 20 published studies of dental calculus and vessel residues, revealing that modification-induced sequence permutations occurred almost ten times more frequently than previously reported.

3/5
💻 The Demodifier simulates all possible modification-induced sequence permutations caused by deamidation (NQ) and N-terminal pyroglutamic acid formation, and assigns lowest common taxonomic ancestors via the Unipept API.

2/5🧵
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.

1/5🧵
🚨 New open access paper out today🚨
The Demodifier: a tool for screening modification-induced alternate peptide taxonomy in palaeoproteomics.
doi.org/10.1371/jour...
#palaeoproteomics

2/5
🧪 Protein modifications such as deamidation and N-terminal pyroglutamic acid formation can change peptide sequences and affect taxonomic assignment in palaeoproteomics.

Garrod Seminar Series 4 December 2025 Amanda Logan Northwestern University An Archaeology of Food Security in West Africa

Join us this Thursday for ‘An Archaeology of Food Security in West Africa’ with Amanda Logan from Northwestern University

📅 Thursday 4 December 2025
⏰ 4pm

bit.ly/garrodseminars2025

Organised by @mirandaevans.bsky.social, Akshyeta Suryanarayan and Alex Weide

Join us this Thursday for ‘The Transition Revisited: Exploring the Culinary Origins of Agriculture in Southwest Asia’ with Amaia Arranz Otaegui from @ehu.eus

📅 Thursday 27 November 2025
⏰ 4pm

bit.ly/garrodseminars2025

Organised by @mirandaevans.bsky.social, Akshyeta Suryanarayan and Alex Weide

Garrod Seminar Series Poster 20 November, 4pm Michelle Alexander Beyond Faith? Biomolecular Insights into Foodways in Multifaith Medieval Mediterranean Societies

Join us for ‘Beyond Faith? Biomolecular Insights into Foodways in Multifaith Medieval Mediterranean Societies’ with Michelle Alexander from University of York

📅 Thursday 20 November 2025
⏰ 4pm

bit.ly/garrodseminars2025

Organised by @mirandaevans.bsky.social, Akshyeta Suryanarayan and Alex Weide

Garrod Seminar Series 13 November 2025 Erica Rowan Tasting the Past: Sensory Archaeology and Roman Foodways

Join us this Thursday for ‘Tasting the Past: Sensory Archaeology and Roman Foodways’ with Erica Rowan from Royal Hollaway, University of London

📅 Thursday 13 November 2025
⏰ 4pm

👉 More info and how to join online: bit.ly/garrodseminars2025

Garrod Seminar Series 6 November 2025 Umberto Albarella Meat Consumption and the Shaping of Romano-British Culture

Join us this Thursday for ‘Meat Consumption and the Shaping of a Romano-British Culture’ with Umberto Albarella from @sheffielduni.bsky.social

📅 Thursday 6 November 2025
⏰ 4pm

👉 More info and how to join online: bit.ly/garrodseminars2025

Garrod Seminar Series 23 October Ester Oras Pots, Bones and Biomolecules: Multiproxy Dietary Reconstructions in the Baltic Region

Join us this Thursday for ‘Pots, Bones and Biomolecules: Multiproxy Dietary Reconstructions in the Baltic Region’ with Ester Oras from University of Tartu

📅 Thursday 23 October 2025
⏰ 4pm

👉 bit.ly/garrodseminars2025

Organised by @mirandaevans.bsky.social, Akshyeta Suryanarayan and Alex Weide

Please join us online or in person for this term's Garrod Seminar Series 'Consumed by time: Past foodways in practice' @cam-archaeology.bsky.social.
We are delighted to have an amazing line up of experts in their field speaking. More details here: talks.cam.ac.uk/show/index/1...

Thank you! I love making posters. The skull is a flap, which reveals CT scans when raised.

Having a blast at BABAO! @babao2025meeting.bsky.social
Thanks everyone who came and saw our poster "The Curious case of the Candia skull: demography revealed by minimally invasive methods" @drtrishbiers.bsky.social

1/3 New recommendation: Miranda A. Evans‬ (2025) The Demodifier: a tool for screening modification-induced alternate peptide taxonomy in palaeoproteomics. ver.4 recommended by @pciarchaeology.bsky.social doi.org/10.1101/2025... 🧪🏺🦣

Delighted to report that my manuscript "The Demodifier: a tool for screening modification-induced alternate peptide taxonomy in palaeoproteomics" has been recommended by PCI.

The Demodifier, an open source tool, screens for inaccurate taxonomic matches caused by PTMs www.biorxiv.org/content/10.1...

Thank you @isba11.bsky.social for a fantastic conference!!! I can't wait to find out where the next one is.
And thank you to everyone who came to my talk "The Demodifier: a tool for screening modification-induced alternate peptide taxonomy in ancient protein studies".

🍝Our next PAASTA Seminar Series talk will be next week Wednesday 02 July at 15:00 CET! 🍝

@mirandaevans.bsky.social will be presenting "The Proteomics of Pottery: What can dirty dishes tell us about ancient diet and cuisine?"

As always, DM us for the Zoom link to join!

New review paper by @mirandaevans.bsky.social
explores how #palaeoproteomicis is revolutionizing our understanding of how ancient people cooked 🏺

Future directions include developing minimally invasive sampling methods, better authentication techniques, and understanding preservation.

Metaproteomic approaches to ancient foodways: A review Proteomic approaches to understanding ancient foodways have rapidly expanded in recent years, addressing diverse questions, regions and sample types. …

New paper out now📣

In this paper, now published in the Next Generation Archaeological Science special issue in JAS, I review the development and current state of the field of metaproteomic approaches to ancient foodways. 🏺🦷🥛🍲🧪 #palaeoproteomics
www.sciencedirect.com/science/arti...

3/3: In archaeology this is important because we are often trying to answer questions about which species were used by ancient people. The results show that this issue occurred 15% more frequently than currently reported.
www.biorxiv.org/content/10.1...

2/3: This is an issue in #palaeoproteomics because it can make it look like there is evidence for one taxon when in fact it could actually be a completely different one.

www.biorxiv.org/content/10.1...

The De-Modifier: a tool for screening modification-induced alternate peptide taxonomy in palaeoproteomics In palaeoproteomic research, the accuracy of taxonomic matches is crucial, as research questions frequently hinge on which species were utilised by ancient people. However, protein modifications inclu...

1/3: Excited to share my new preprint, out today!
In it I share a tool I have created which screens for potentially spurious peptide taxonomies caused by post translational modifications.
www.biorxiv.org/content/10.1...

Congratulations @isma-rgz.mastodon.social.ap.brid.gy on your first 1st-author paper.

Gets even better because it's with our favourite protein ever @matthewcollins.bsky.social @mirandaevans.bsky.social, eh!?

Apparently I talk with my hands. Thanks for having me to present on "The Proteomics of Pottery: what can dirty dishes tell us about ancient diet and cuisine?" at the Pudding Seminar, @Newnham_College!

Great Job Ismael, Bharath and others!
Fantastic insights into optimal search strategies in palaeoproteomics.