Vladimir Reinharz's Avatar

Vladimir Reinharz

@vreinharz

Prof, RNA, Algorithms, Evolution

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08.09.2023
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Latest posts by Vladimir Reinharz @vreinharz

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AI Translations Are Adding ‘Hallucinations’ to Wikipedia Articles AI translated articles swapped sources or added unsourced sentences with no explanation, while others added paragraphs sourced from completely unrelated material.

NEW: Wikipedia editors have implemented new policies and restricted a number of contributors who were paid to use AI to translate existing Wikipedia articles into other languages after they discovered these AI translations added AI “hallucinations,” or errors, to the resulting article.

04.03.2026 14:15 👍 876 🔁 370 💬 16 📌 38
In addition to promoting entertainment, X's feed algorithm tends to push more conservative content to users' feeds. Seven
weeks of exposure to such content in 2023 shifted users' political opinions in a more conservative direction, particularly with regard to policy priorities, perceptions of the criminal investigations into Trump and views on the war in Ukraine. The effect is
asymmetric: switching the algorithm on influenced political views, but switching it off did not reverse users' perspectives on policy
priorities or current political issues.

In addition to promoting entertainment, X's feed algorithm tends to push more conservative content to users' feeds. Seven weeks of exposure to such content in 2023 shifted users' political opinions in a more conservative direction, particularly with regard to policy priorities, perceptions of the criminal investigations into Trump and views on the war in Ukraine. The effect is asymmetric: switching the algorithm on influenced political views, but switching it off did not reverse users' perspectives on policy priorities or current political issues.

We show that exposure to algorithmically curated content led users to follow conservative activist accounts. In contrast, when the algorithmic feed was switched off, users continued to follow the accounts they had engaged with previously. This indicates that exposure to feed algorithms has a lasting impact on users' feeds and their political attitudes.

We show that exposure to algorithmically curated content led users to follow conservative activist accounts. In contrast, when the algorithmic feed was switched off, users continued to follow the accounts they had engaged with previously. This indicates that exposure to feed algorithms has a lasting impact on users' feeds and their political attitudes.

This is a very interesting new paper in Nature about the role that feed algorithms on X play in influencing political attitudes.

No paywall: www.nature.com/articles/s41...

18.02.2026 19:35 👍 439 🔁 162 💬 11 📌 26
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A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?

Excited to share our latest work in @science.org on a new small polymerase.
1/n

13.02.2026 11:42 👍 497 🔁 209 💬 10 📌 28
At the top, a participant of the Mascara Festival smiles while wearing traditional attire. In the bottom, people smiling and dancing during the Sandurot Festival. Text says: Happy 25th birthday, Wikipedia!

At the top, a participant of the Mascara Festival smiles while wearing traditional attire. In the bottom, people smiling and dancing during the Sandurot Festival. Text says: Happy 25th birthday, Wikipedia!

Twenty-five years ago, Wikipedia was an unlikely idea: a place where anyone could share free knowledge.

Today, it’s one of the most visited sites on Earth, not powered by corporate ads, but by people.

15.01.2026 10:58 👍 197 🔁 86 💬 3 📌 16

Best explanation of the liar's dividend that I've ever seen.

24.12.2025 06:36 👍 2078 🔁 443 💬 7 📌 0

It’s insulting to tell 🇨🇦 scientists we need international scientists to run to our rescue & ensure innovation.

🇨🇦 scientists have exceeded expectations with paltry funding. If the gov funded Tricouncil > & sustainably; imagine how innovative we’d already be!! /End

05.11.2025 03:58 👍 47 🔁 15 💬 1 📌 2

Canadian researchers should be aware the there is a motion before the Parliamentary Standing Committee on Science and Research to force Tricouncils to hand over disaggregated peer review data on all applications:
Applicant names, profiles, demographics
Reviewers names, profiles, comments, and scores

30.10.2025 20:33 👍 144 🔁 170 💬 13 📌 50
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Cryo-EM structure of the naked mole-rat ribosome reveals a stabilized split 28S rRNA The naked mole-rat (Heterocephalus glaber) is a long-lived mammal with remarkable resistance to cancer and hypoxia, suggesting the evolution of robust proteostasis networks. The ribosome, the central ...

We have a new preprint for you. Naked mole rats are very long-lived rodents and have increased translational fidelity.

Interestingly, 28S ribosomal RNA is split. Here we investigated the structure of the ribosome by single particle cryo-EM. Take a look.
www.biorxiv.org/content/10.1...

28.10.2025 15:24 👍 49 🔁 12 💬 2 📌 1
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Largest study of its kind shows AI assistants misrepresent news content 45% of the time – regardless of language or territory An intensive international study was coordinated by the European Broadcasting Union (EBU) and led by the BBC

Yet again, we can't afford to let LLMs become a source of epistemic grounding for society.

24.10.2025 05:21 👍 2198 🔁 924 💬 25 📌 58

To use it like this is to teach children that a statistical composite is better than their own imagination.

It is morally wrong on that basis alone, before you even get to all the harm required to produce it

23.10.2025 17:19 👍 238 🔁 28 💬 2 📌 0
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The chemistry community should ban drawing chemical structures with generative AI, chemists warn AIs like Microsoft's Copilot, Google's Gemini and OpenAI's ChatGPT still make serious errors rendering structural formulae

Chemists call for ban on generative AI for chemical structures: "serious errors could damag[e] the next generation of scientists"

As ever, the problem seems to be not AI but lazy application of it and lack of checks. Whether _that_ problem is solvable...

www.chemistryworld.com/news/the-che...

16.10.2025 12:10 👍 31 🔁 12 💬 3 📌 3
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RNA3DB 2025-10-01 release
github.com/marcellszi/r...
#RNA #RNAsky

The database of all RNA chains in PDB arranged in structurally disimilar components, including Rfam annotation.

More chains (25,666), more independent components (144), more Rfam families represented (853).

10.10.2025 15:51 👍 6 🔁 4 💬 1 📌 0
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New Study Shows How Paris Pedaled Its Way to a Cycling Revolution Cycling through central Paris meant weaving between buses and scooters—a bold choice reserved for the fearless few.

“The transformation is astonishing. [Paris] has quietly—& quickly—become one of the most bike-friendly cities in the world. What started as a series of emergency “coronapistes” or pop-up bike lanes, built during the pandemic has evolved into a permanent bike network spanning hundreds of kilometres.”

10.10.2025 14:58 👍 888 🔁 227 💬 14 📌 16

This is the lie at the center of the "demographic crisis" framing. In the US, per worker productivity has tripled since the 1960s. But instead of increasing compensation or various forms of dependent care, this **enormous** new surplus goes to private profits, asset inflation, and rent extraction...

08.10.2025 16:38 👍 18 🔁 7 💬 1 📌 0

TIL You can whistle a language!
On La Gomera (one of the Canary Islands), Silbo Gomero encodes Spanish into whistles that carry across valleys for kilometres!

It’s taught in schools since 1999 and considered a Masterpiece of the Oral and Intangible Heritage of Humanity by UNESCO

07.10.2025 14:00 👍 6 🔁 1 💬 0 📌 0
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All-at-once RNA folding with 3D motif prediction framed by evolutionary information - Nature Methods Structural RNAs exhibit a vast array of recurrent short three-dimensional (3D) elements found in loop regions involving non-Watson–Crick interactions that help arrange canonical double helices into tertiary structures. Here we present CaCoFold-R3D, a probabilistic grammar that predicts these RNA 3D motifs (also termed modules) jointly with RNA secondary structure over a sequence or alignment. CaCoFold-R3D uses evolutionary information present in an RNA alignment to reliably identify canonical helices (including pseudoknots) by covariation. Here we further introduce the R3D grammars, which also exploit helix covariation that constrains the positioning of the mostly noncovarying RNA 3D motifs. Our method runs predictions over an almost-exhaustive list of over 50 known RNA motifs (‘everything’). Motifs can appear in any nonhelical loop region (including three-way, four-way and higher junctions) (‘everywhere’). All structural motifs as well as the canonical helices are arranged into one single structure predicted by one single joint probabilistic grammar (‘all-at-once’). Our results demonstrate that CaCoFold-R3D is a valid alternative for predicting the all-residue interactions present in a RNA 3D structure. CaCoFold-R3D is fast and easily customizable for novel motif discovery and shows promising value both as a strong input for deep learning approaches to all-atom structure prediction as well as toward guiding RNA design as drug targets for therapeutic small molecules.

Integrated prediction of RNA secondary structure jointly with 3D motifs and pseudoknots guided by evolutionary information.
@aakaran31.bsky.social and @rivaselenarivas.bsky.social

link.springer.com/article/10.1...

03.10.2025 12:42 👍 22 🔁 10 💬 0 📌 2
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I get that the news cycle is packed right now, but I just heard from a colleague at the Smithsonian that this is fully a GIANT SQUID BEING EATEN BY A SPERM WHALE and it’s possibly the first ever confirmed video according to a friend at NOAA

10 YEAR OLD ME IS LOSING HER MIND (a thread 🧵)

24.09.2025 20:30 👍 29693 🔁 9979 💬 727 📌 1545
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RFdiffusion3 is here! We train a general network that explicitly models every atom and use it to design active enzymes and DNA binders.

Tremendous team effort with Jasper, Rohith, Raktim, Rafi, Yanjing, Paul, Jonathan, and many others!

Check it out: lnkd.in/eiUFfJaM.

19.09.2025 15:45 👍 31 🔁 9 💬 1 📌 0
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Dryad partnership brings easier data sharing to bioRxiv bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

bioRxiv partners with Dryad to enable easier, better linking to curated datasets connect.biorxiv.org/news/2025/09...

18.09.2025 19:43 👍 55 🔁 35 💬 2 📌 2

forgot to include link to our looooooooong miRNA hairpin saga. pls share with your miRNA geek friends and let us know what you think! in the meantime, here's a picture of stretch armstrong i pulled from the interweb.

www.cell.com/cell-reports...

12.09.2025 02:09 👍 20 🔁 8 💬 1 📌 0
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Genomics in Context Awards - Research Funding | Wellcome These awards will support transdisciplinary teams to catalyse research discoveries at the intersection of genomics, humanities, social sciences and bioethics.

Our Genomics in Context Awards will support these new transdisciplinary teams.

Learn more at our webinar on 18 November ⤵️
wellcome.org/research-fun...

10.09.2025 15:42 👍 6 🔁 2 💬 0 📌 0

The “problem” with vaccines? They so effective at preventing deaths that they create generations of people that question whether disease was a problem in the first place because they have never experienced the horrors of a world without vaccines.

04.09.2025 19:44 👍 26703 🔁 7803 💬 577 📌 457
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We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

04.09.2025 08:21 👍 347 🔁 118 💬 16 📌 8
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🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵

Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open.

doi.org/10.1101/2024...

03.09.2025 08:39 👍 218 🔁 118 💬 3 📌 16

Congrats to my better half @legionella.bsky.social and his lab and collaborators on this cool discovery! TLDR, they've identified and re-animated a bacteriophage of Legionella pneumophila, a bacteria long thought to not be susceptible to phage attack. Check it out! 🦠

03.09.2025 22:26 👍 12 🔁 3 💬 0 📌 0
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Starting the last day of #ARNASydney2025 with the RNA Processing and Modifications session. First, @edueyras.bsky.social, who is developing pipelines to identify #RNA modifications in using @nanoporetech.com

👀 this preprint on the conservation of RNA modifications:

www.biorxiv.org/content/10.1...

02.09.2025 23:53 👍 6 🔁 2 💬 1 📌 0
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Important reading as you prepare for your semester

31.08.2025 00:10 👍 368 🔁 104 💬 7 📌 9
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How Viktor Orbán Wins | Journal of Democracy The case of Hungary shows how autocrats can rig elections legally, using legislative majorities to change the law and neutralize the opposition at every turn, no matter what strategy they adopt.

But it was too late. To understand what happened, you *must* read @kimlanelaw.bsky.social's @jodemocracy.bsky.social article ▼▼

In fact, just drop what you're doing and read it now.

30.08.2025 20:10 👍 667 🔁 173 💬 16 📌 10

Another impressive dissection of tRNA modification consequences from Sarah Schultz in Ute Kothe's lab. Her work reveals that even though TrmA, TruB, or now DusA KOs show no overt growth phenotypes, modifications they deposit have real impacts on tRNA charging and codon-specific translation.

30.08.2025 18:15 👍 9 🔁 1 💬 0 📌 0
Uncovering the multi-layer cis-regulatory landscape of rice via integrative nascent RNA analysis

🚨 New paper in the lab! 🌾

Thrilled to share our latest article published in Genome Biology!
👉 rdcu.be/eBh6j

👏 Congrats to the students for their remarkable contributions! A real pleasure collaborating with @aepina2.bsky.social, P. Edger, @jychoi.bsky.social & M. Purugganan on this project.

30.08.2025 13:55 👍 7 🔁 2 💬 0 📌 0