Length distribution of non-autonomous LTR retrotransposons
Our lab member Sophie deep-dived into the genome of one of the plants we know best (sugar beet).
She identified over 100 non-autonomous LTR retrotransposon families hiding in the genome. Many elements are rather long (length distribution β¬οΈ), often without any sequence similarity to coding TEs.
#TEworldwide #TEsky
#TEsky a short paper from @mbonar.bsky.social , myself and others on our reannotation of TEs in the Octopus vulgaris genome. More work to come using genome ecology to analyze TEs in this species bsky.app/profile/bior...
Just over ten years after the discovery of the first Asgard archaeal genomes, we revisit the rapid expansion of this remarkable archaeal lineage. From diverse genomes and metabolisms to eukaryotic signature proteins and the first cultured representatives.
www.nature.com/articles/s41...
Dauphin et al. assembled a telomere-to-telomere reference genome for an ectomycorrhizal fungus with a large, repeat-rich genome, showing its genome expansion was driven by a few lineage-specific TE families in recent history.
π doi.org/10.1093/gbe/evag017
#genome #evolution #TEsky
Top: Subcellular localization of Cap1-GFP in wild-type background (top, tetO-CAP1-GFP/CAP1), Cap1-GFP with C446* (middle, TeO-CAP1C446*-GFP/CAP1) and wild-type Cap1-RFP (bottom, CAP1C446*/TeO-CAP1-RFP) in CAP1/CAP1C446* background. Scale bar, 5 ΞΌm. Bottom: Schematic of subcellular localization and transcription activation of CAP1 in wild-type (CAP1/CAP1, left) and CAP1/CAP1C446*. Figure generated with BioRender.
#Azole resistance in #Candida albicans poses a growing threat, and is linked to #StressResponse. @annaselmecki.bsky.social &co show that mutations in the oxidative stress TF Cap1 promote #DrugResistance while exposing a lethal vulnerability at high azole doses @plosbiology.org π§ͺ plos.io/4rOrfOz
I have a postdoc position in metagenomic exploration available in my group. Candidates with documented experience in phylo & metagenomics and preferably with petabase-scale data mining and GLM workflows are encouraged to apply. Come join us! π§¬π¦ π»
Please repost
Apply here: www.wur.nl/en/vacancy/p...
Now officially published in Current Biology π₯³π₯³ @mfseidl.bsky.social @binfutrecht.bsky.social
www.cell.com/current-biol...
Extensive horizontal transfer of transposable elements shapes fungal mobilomes
@currentbiology.bsky.social by @jromeijn.bsky.social et al from @mfseidl.bsky.social
www.cell.com/current-biol...
Our paper on Zymoseptoria tritici 3D genome organization is officially out! @iglavincheska.bsky.social
link.springer.com/article/10.1...
The best two things in one database: Transposons and Fungi
1/ Ever needed to annotate TEs in a fungal genome, but didn't know where to start?
We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes!
www.biorxiv.org/content/10.1...
Such wonderful news, this is so well deserved! All the best for this next step!
Want to understand how entire fungal chromosomes can be horizontally transferred?
Join us to unravel the mechanism/consequences of horizontal chromosome transfer in a fungal pathogen as part of an ERC-funded project. Postdoc/PhD positions available.
fungal-evolutionary-genetics.de/open-positio...
Widespread shifts in genome architecture and trophism across fungi. Phylogenetic positions of the shifts identified for genome size. Negative values denote an identified decrease in the genomic trait value while positive values denote an increase in the genomic trait value.
Fungal #GenomeSize variation is largely driven by TEs & lineage-specific genome defenses. @tbadet.bsky.social & @danielcroll.bsky.social show that presence/absence of RIP mutation systems influences #genome architecture, identifying a likely novel defense mechanism @plosbiology.org π§ͺ plos.io/4hcC5tx
At its meeting of 17 and 18 September 2025 and upon application of JoΓ«l Mesot, President of ETH Zurich, the ETH Board appointed eight professors. The Board also awarded the title of "Professor of Practice" once.
More info:
The first paper of my PhD is now available as a preprint! π
Transposable elements (TEs) don't just jump within fungal genomes, they also move extensively between species. In this study, we screened over 1,300 fungal genomes and found a conservative estimate of 5,500+ horizontal transfer events.
Happy Barbara Day, happy #TransposonDay2025 to all that celebrate! Every day we get to work on transposons is such a privilege and joy, and I will never not be amazed by these jumping weirdos -the neutral, the bad and the good. Share some black walnut brownies with your friends today!
For those interested in repeat-induced point mutations (RIP) in fungi: Thomas Badet set up an amazing meeting in beautiful NeuchΓ’tel #TEsworldwide #Transposon
π₯ The event will bring together molecular biologists, evolutionary geneticists, and bioinformaticians to explore RIPβs role in transposable element control, genome integrity, and fungal adaptation.
Looking forward to seeing you in NeuchΓ’tel! ποΈ #RIPM2025 #FungalGenomics #EvolutionaryBiology
π₯ Exciting news! The first Symposium on Repeat-Induced Point mutations is happening June 30 β July 1 at the University of NeuchΓ’telπ¨π!
πΉ Want to join? Register here > forms.gle/XWTd4gJAXZSx...
π¨ Limited spots available! So first come, first served!
πΉ More info > crolllab.github.io/ripm2025/
@guidopuccetti.bsky.social, Gabriel Scalliet and I are excited to share our latest work.
Resistance in agriculture emerges fast, but we fail to grasp how the myriad mutations in pathogen populations contribute to this.
Please check out and share our latest preprint: www.biorxiv.org/content/10.1...
Barbara McClintock also spent some time working on fungi (Neurospora), so it is more than fair to keep on mentioning her
Honestly I am worried about the impact Trump policies will have on the future of third world PhD students who wants to do it abroad. Americans leaving for Europe will make the process even more harder for people coming from developing and underdeveloped nations.
It is similar in Switzerland, and beyond advertised positions, cold calls with a good letter of specific interest for a lab are possible as well. I liked that it is a job, not continuation of school. And as a plus, there are amazing mountain hikes and rock climbing on the weekends!
Illustration of FuSpok killing a cell which has lost an accessory chromosome. Core chromosome in blue, accessory chromosome in red. Black circle: FuSpok. Green circle: antidote function. Red triangle: toxin function.
Interested in #fungal accessory chromosomes or toxin/antidote genes? Check out our new preprint! We show that the Spok gene family in Fusarium include active toxin/antidote genes. We present a model for how these genes influence the evolution of fungal genomes. www.biorxiv.org/content/10.1...
This goes on the top of my break reading list! It has everything that could be asked for: Starships! Transposable elements! Fungi! And an amazing group of scientists! #TEsky #transposons
#TEsky Please circulate! The interdisciplinary research group I'm part of is looking for two postdocs to work on transposons with us here at the U of Guelph in Ontario Canada. philjobs.org/job/show/28330
A researcher on a boardwalk in a DANK hawaiian forest on Molokai.
RP PLS! IΚ»m hiring 3 postdocs at U HawaiΚ»i to study yeast diversity and evolution, marine fungi, and the genomics of microbiomes in experimental foodwebs. All of these projects have existing datasets and LATITUDE to pursue individual interests and "blue sky" ideas www.dropbox.com/scl/fi/5d7u4...
If you like #Transposons πΎ check out this feed and tag your posts with #TEsky! Thanks @tobybarilbio.bsky.social π€ bsky.app/profile/did:...
