Beautiful desert views. Beautiful membrane biology.
Join us for the #FASEB Phospholipids in Aging and Disease SRC in Arizona, July 26–30 2026. Registration is now open!
So much better than a Lipid Droplets conference. Also, we're co-located with FASEB Lipid Droplets 😜
To all lipid-curious cell biologists: check out this comprehensive overview of lipid-based methods by @gerryhammond.bsky.social and colleagues in @jcb.org — a school of Babel fish for #lipidtime:
rupress.org/jcb/article/...
🍨Interested in reading more about the study? Here is the N&Vs article written by Michael Salsaa & Gregory D. Fairn.
👉https://rdcu.be/eADFu
bit.ly/45zxHiL
🍹 @grahamlab-vandy.bsky.social @jainbhawik.bsky.social & co report that the Neo1 P4-ATPase flips the #lipid PI4P across the #Golgi membrane to the cytosolic leaflet, preventing PI4P exposure and thereby conferring neomycin resistance.
bit.ly/45tauP7
@vai.org @vubasicsciences.bsky.social @vanderbiltvicb.bsky.social
#flippase #membrane-transport #neomycin #lipid transport
Our study explains why yeast cells lacking Neo1 are neomycin sensitive, which targets PI4P when it is exposed on the outer leaflet of the plasma membrane. We show that Neo1 flips PI4P, offering key mechanistic insight into how phosphoinositide membrane asymmetry is maintained. @vuartsci.bsky.social
Excited to share our latest work published in @natcellbio.nature.com! We identify Neo1 as a novel phosphoinositide flippase that maintains membrane asymmetry and provides resistance to neomycin.@grahamlab-vandy.bsky.social. Check out the article and News & Views here
rdcu.be/eweby
rdcu.be/eweh9
As April comes to a close, we wanted to share updates for the first quarter of 2025!!
