An early Christmas present from our team for all of the tomato π
& recombination fans:
Chromosome-scale Solanum pennellii and Solanum cheesmaniae genome assemblies reveal structural variants, repeat content and recombination barriers of the tomato clade
biorxiv.org/content/10.648β¦
Our study on COmapper using nanopore long-read sequencing is now published online! (see New Phytologist: nph.onlinelibrary.wiley.com/doi/10.1111/...) Congratulations to lead author Dohwan Byun, soon-to-be Dr. Namil Son, and the co-authors!
Paper alert! #Meiosis4Ever
Maximizing meiotic crossover rates reveals the map of Crossover Potential
Juli Jing, Qiachao Lian and Stephanie Durand
www.nature.com/articles/s41...
We pushed meiotic crossover as much has we could, and had some surprises
A thread π
"Haploid induction in sweet potato by activating the
AP2/ERF family transcription factor IbBBM"
From: onlinelibrary.wiley.com/doi/full/10....
Since sweet potato is hexaploid, the corresponding haploid is actually triploid then?
Excited to share that our COmapper preprint on bioRxiv has been updated following two rounds of major revisionβthanks to insightful peer reviews! biorxiv.org/content/10.1...
COmapper is now even betterβcheck it out on GitHub: github.com/KyuhaChoi-La...
Journal version coming soon!
It is sad that even basic research needs to be defended with utility. For me, basic research is in the same category as art: civilized societies can't do without it, because we all want to know who we are and what our place in the natural world is -- questions that only science can answer.
Please see our latest paper on the role of EXO1 in meiosis: "EXO1 promotes the meiotic MLH1-MLH3 endonuclease through conserved interactions with MLH1, MSH4 and DNA". Congratulations to both first authors, Megha Roy and Aurore Sanchez and thanks to all our collaborators!
We have a complete program !
meiosis.cornell.edu/mayosis2025/...
The #Mayosis25 seminar series will open with a tribute to Scott Hawley by @jeffsekelsky.bsky.social.
Congrats to all the selected speakers and we look forward to hearing about your fantastic science !
#Meiosis4ever
New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the TuroΕovΓ‘ lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv π§΅π
Excited to share our preprint on the molecular architecture of heterochromatin in human cells π§¬π¬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, TuroΕovΓ‘ lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social
π Preprint here tinyurl.com/3a74uanv
Thanks Pierre!
Thrilled to announce our study on the histone variant H2A.W & pericentromeric crossovers is now out in PNAS! We show that loss/knockdown of H2A.Ws boosts meiotic crossovers in Arabidopsis pericentromeric regions: www.pnas.org/doi/10.1073/...
Nature research paper: Haploid facultative parthenogenesis in sunflower sexual reproduction
https://go.nature.com/4hYpSY3
New Perspective: "The future of genome editing in plants" rdcu.be/ef8aa
Genome editing will mimic the natural evolutionary processes that shape genomes; will be used to reshape genomes in a manner that could have happened naturally, but more precisely and more rapidly.
Paper "Triploid bridges enable gene flow in mixed-ploidy populations of Cardamine amara" published in Molecular Ecology! doi.org/10.1111/mec....
The study reveals how rare triploids help overcome ploidy barriers and mediate gene flow between diploid and tetraploid populations.
Uncalled4: a toolkit for nanopore signal alignment, analysis and visualization of DNA and RNA modifications.
www.nature.com/articles/s41...
Drosophila follicle showing retrotransposons (pink & yellow) expressed in somatic cells infecting the oocyte
1/ Transposable elements are often called "jumping genes" because they mobilize within genomes. π§¬
But did you know they can also jump π£π¦π΅πΈπ¦π¦π― cells? π€―
Our new study reveals how retrotransposons invade the germline directly from somatic cells.
www.biorxiv.org/content/10.1...
A short thread π§΅π
Illustration depicting the ways in which fungi can exchange genetic material with each other. Starship mediated HGT is confirmed experimentally in this preprint.
We did it! We caught Starship #transposons moving between #fungal species in the lab, including between species separated by ~100my. We think Starships are a mediator of HGT in fungi, akin to conjugative elements in bacteria. Check out the preprint. www.biorxiv.org/content/10.1...
Our new review article βTo infinity and beyond: recent progress, bottlenecks, and potential of clonal seeds by apomixisβ is now published open access in @theplantjournal.bsky.social
dx.doi.org/10.1111/tpj.... @ribesresearch.bsky.social
I am thrilled to share our new review on holocentric chromosomes. It was a lot of fun to write it together with Ines Drinnenberg!
Same but different: Centromere regulations in holocentric insects and plants doi.org/10.1016/j.ce...
Do you love meiosis? Have a cool story to share? Join us for the XVth British Meiosis Meeting 26-27 of March in Liverpool! docs.google.com/forms/d/e/1F... You only have till Sunday to submit an abstract for a talk! ECRs are prioritised for speaking slots so the odds are in your favour π #meiosis4eva
π₯³Just published @nature.com. Over 25 years after the discovery of SPO11 as the enzyme responsible for initiating meiotic recombination, we finally succeeded in reconstituting its DNA cleavage activity.π§΅
www.nature.com/articles/s41...
Thank you Charlie for visiting us and giving a fantastic talk!
Looking forward to an exciting conference at POSTECH - Korean Society of Plant Biologists. Thank you to @kyuhachoi.bsky.social for the invitation.
