Vardilab

Response to heat stress is mediated by reactive oxygen species accumulation that is enhanced in PtMCA-III triple KO mutants.

Metacaspases contribute to the cellular response to heat stress in a marine diatom

Sadeh et al. @vardilab.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...

In this study, we used #metabolomics to trace #viral infections in #coccolithophore blooms across the Atlantic analyzing data from four cruises including the #TARA Breizh and #TARA Gayoso expeditions.
@taraoceans-science.bsky.social @wisdeppes.bsky.social
#MicroSky #VirusSky 🌊

Mapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers | PNAS The viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events ...

🌊Paper announcement! 📣
Viral infections rewire the metabolic makeup of their host and thereby create distinct chemical signatures. Can we use metabolic biomarkers to diagnose infections of algal blooms in the ocean?
Well, take a look at our new article led by Conny Kuhlisch in @pnas.org
>>

We even made a video! Created by #NotebookLM
#Scientists_desperate_to_solve
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The core-resistance genes could serve as potential markers to detect resistant cells during algal blooms. A better understanding of algal resistance mechanisms is key to unraveling the host-virus arms race in the ocean and bloom dynamics. 🌊 >>

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Mapping the transcriptional landscape of algal resistance to viral infection reveals a core expression program Algal blooms and their demise by viruses drive global-scale ecological processes in the ocean. These blooms form the foundation of marine food webs, regulate microbial communities, and shape biogeoc...

📣 We are excited to share our latest paper, led by @taliashaler.bsky.social! We explore the transcriptional basis of #microalgae resistance to #viral_infection and identified a core group of resistance-related genes. >>
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#New_Phytologist #Marine_Biology #Viruses

Synergy in viral-bacterial coinfection expedites algal bloom demise www.biorxiv.org/content/10.1...

Good idea !

Thanks a lot Oded!!

Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO Sixty-nine new members join the community of leading life scientists in Europe and beyond

Congratulations to Asaf Vardi @vardilab.bsky.social for being elected to EMBO. microbial ecology rock!!!
www.embo.org/press-releas...

Metacaspases mediate thermotolerance of diatoms following marine heat waves www.biorxiv.org/content/10.1... #jcampubs

Increasing complexity in the analysis of host–virus interactions.

Single-cell transcriptomics reveals population heterogeneity

Advancements in single-cell technologies are opening new frontiers in marine microbiology, helping us answer some of the most fundamental questions in marine microbiology and providing a holistic view of microbial life in the ocean.

A single-cell perspective on host–virus dynamics in the ocean Viral infections of marine microbes greatly impact ecological and biogeochemical processes. Typically, these host–virus interactions are studied at th…

📣Excited to share our latest review on using single-cell methods to study host-virus interactions in the ocean - led by Amir Fromm (@amirfromm.bsky.social) and Talia Shaler (x.com/ShalerTalia), in collaboration with Frank Aylward (@foaylward.genomic.social.ap.brid.gy) >>

A single-cell perspective on host–virus dynamics in the ocean Viral infections of marine microbes greatly impact ecological and biogeochemical processes. Typically, these host–virus interactions are studied at the population level using bulk transcriptomics, whi...

A single-cell perspective on host–virus dynamics in the ocean

@cp-trendsmicrobiol.bsky.social Opinion from @vardilab.bsky.social

www.cell.com/trends/micro...

>> The expression of these resistance-related genes was found to be shared among various resistant strains and included genes with domains linked to innate immune responses that are conserved across bacteria, plants and mammals. 🦠🌊

Mapping the transcriptional landscape of algal resistance to viral infection reveals a core expression program ### Competing Interest Statement The authors have declared no competing interest. Simons FoundationSimons Foundation, https://ror.org/01cmst727, 150809

📣A new preprint by Talia Shaler! 📣
How do populations develop resistance to viral infections?
We mapped the transcriptomic landscape of algal resistance to lytic viral infection and identified a unique set of resistance-related genes expressed in those cells >>
doi.org/10.1101/2025...

Cathepsin X mutants in distant algae had increased resilience to oxidative stress. Our findings shed light on the origin of programmed cell death in unicellular organisms and their strategies to cope with environmental fluctuations. 3/3

Using cell-to-cell heterogeneity in response to oxidative stress, we discovered genes linked to either cell death or stress resilience in diatoms. Among the hits we detected was Cathepsin X, a cysteine protease conserved from humans to algae and widely expressed in the oceans. 2/3 >>

Cathepsin X is a conserved cell death protein involved in algal response to environmental stress Phytoplankton are responsible for half of the global photosynthesis and form vast blooms in aquatic ecosystems. Bloom demise fuels marine microbial li…

📣 We are excited to share our latest paper about Cathepsin X, a new algal cell death gene, led by @aviamizrachi.bsky.social and @maisadeh.bsky.social, published in Current Biology @currentbiology.bsky.social www.sciencedirect.com/science/arti... 1/3 >>