Vinegar to biofuels: using acetate as a co-carbon source for isoprenol in Pseudomonas putida. Out today in AEM journals.asm.org/doi/10.1128/...
20.03.2025 20:22
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Vinegar to biofuels: using acetate as a co-carbon source for isoprenol in Pseudomonas putida. Out today in AEM journals.asm.org/doi/10.1128/...
And of course I have to thank our fearless TEA gurus Nawa Baral and @cdscown.bsky.social for their amazing critical analysis on the economics of bioconversion processes.
Are graphical abstracts still too long?! How about a chatbot-generated Haiku?
"Isoprenol's sweet rise
Biosensors guide the way
Fuel for future skies"
There's a new chatbot attached to preprints -- you can ask it questions about the paper here:
sciencecast.org/casts/dy9n40...
Just deposited! New preprint about modular workflows, biosensors for biofuels, and HT screening. Thanks to all my coauthors and @berkeleylab.lbl.gov @biosci.lbl.gov @jgi.doe.gov
I have been delinquent in posting birds lately. I'll try to do better.
For now, two brown pelicans near Santa Barbara. 🪶
Hawaiian crows are extinct in the wild and are found nowhere else on Earth. Now, a small group, safeguarded in captivity, has been released in the forests of Maui.
I can’t remember where I read this, but it’s important:
Why is it that when people think about traveling to the past, they worry about doing something small that will drastically change the present, but no one in the present thinks that doing something small today can drastically change the future?
Your lab scissors are actually a parafilmase - a highly specialized enzyme that catalyzes the precise cutting of parafilm through a metal-dependent mechanism
Not even LinkedIn is immune to becoming a dating simulator
Banner for the DOE Office of Science's SCGSR (Office of Science Graduate Student Research Program) and WDTS (Workforce Development for Teachers & Scientists). The background is green with a geometric design. On the left, the SCGSR and WDTS logos are displayed above bold text reading "GROW YOUR RESEARCH. EXPAND YOUR NETWORK." in white and yellow. On the right, a professional portrait of a smiling woman with curly black hair, glasses, and a black blazer is shown.
Fellowship opportunity for grad students:
DOE Office of Science Graduate Student Research #SCGSR program now open for applications
JGI @jgi.doe.gov is part of @berkeleylab.lbl.gov and can host students. To discuss possible projects, please reach out to our scientists!
science.osti.gov/wdts/scgsr
We just celebrated the opening of the newest building at @berkeleylab.lbl.gov - BioEPIC! Many thanks to the Smith Group, Clark Construction, and UC National Laboratories for your efforts in making this building a reality!
bioepic.lbl.gov
@ucnewsroom.bsky.social
@eesaberkeleylab.bsky.social
Remember that Europe (@ebi.embl.org) has mirrored all these services and they will keep on running. They look and feel a bit different but do the same thing. I think @ewanbirney.bsky.social should be able to confirm.
www.europepmc.org
www.ebi.ac.uk/jdispatcher/...
A portrait of Daisy Roulland-Dussoix from Wikipedia: https://en.wikipedia.org/wiki/Daisy_Roulland-Dussoix
Do you know Daisy Roulland-Dussoix? She is one of the discoverers of restriction enzymes, who’s findings paved the way for the development of recombinant DNA and cloning technologies. Accordingly, the finding was rewarded with a #NobelPrize. But the prize didn’t go to her.
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This is such a huge loss for the meiosis community. Scott provided so much important support when I felt I was yelling into the void about meiotic checkpoints and equity issues. I will miss him 💕
Scene from The Princess Bride where Vizzinni says "You're trying to kidnap what I've rightfully stolen"
OpenAI right now
In fairness, “you can make millions of individual molecules but there are 13 that you need but can’t make so let’s outsource their production to plants. Also, it’s actually 12…you can make one of the vitamins…as long as the sun’s rays touch your skin like you yourself are a plant” does sound fake.
Honoring Senator Skinner at the lab today to celebrate her dedication to renewable energy and energy storage
Thank you Jimmy Carter for one last gift to the nation: flags at half-staff today
starsandstripesdaily.org/half-staff-s...
Our new review article "Microbial secondary metabolites: advancements to accelerate discovery towards application" in Nature Reviews Microbiology is now published!
rdcu.be/d6BHX
Venn diagram illustrating microbial diversity of bacteria and archaea captured by isolates, metagenome-assembled genomes (MAGs) from NCBI and IMG, and metagenomes from IMG. A large portion of microbial diversity, labeled as 'Microbial Dark Matter,' represents species not captured by isolates or MAGs. Image modified from https://www.science.org/doi/10.1126/sciadv.adq2166
Genomes assembled from #metagenomes (a.k.a. MAGs) are awesome and have revolutionized our ability to study uncultivated microbes
...BUT: they still don't capture a lot of the 🦠 species that are out there
New @jgi.doe.gov paper led by Dongying Wu and Natalia Ivanova: www.science.org/doi/10.1126/...
Congratulations to Lab scientists Raúl Briceño, Stefan Wild, and Ahmet Kusoglu for receiving the Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor the US government bestows on early-career scientists and engineers. 🧪
More ⬇️
newscenter.lbl.gov/2025/01/16/t...
Amazing tweetorial!! Looking forward to reading this. Interesting you don’t see partitioning of Ec into quiescent vs non-quiescent populations, like budding yeast from Maggie Werner Washburne pubmed.ncbi.nlm.nih.gov/21289090/ ; do the bulk phenotypes require growth in M9 first or would LB suffice?
If the total number of bacteria on earth stays roughly
constant, then on average there must be as much death as there is growth, suggesting at least naively that selection for surviving starvation is as relevant as for growing fast. But we know relatively little about how bacteria change 2/n
MGM-33 Workshop Lawrence Berkeley National Laboratory 1 Cyclotron Rd Building 91, Room 310 Berkeley, CA 94720 April 28, 2025 - May 2, 2025
Microbial Genomics & Metagenomics Workshop
Want to learn how to use IMG, GOLD, and other @jgi.doe.gov -hosted platforms and tools for microbial and metagenomics?
Register now for the 33rd MGM Workshop in Berkeley
Early bird rates available until Jan 31!
mgm.jgi.doe.gov
This is how phrases become corporate speak like “synergies” and “give you the time back”😅
Yes, we left it a bit vague as we didn’t have a clean answer for this; it might be related to the stirred tank format or the extended nutrient feeding where the overall biomass is considerably increased. Heterologous catabolic pathway with heterologous final product
