Kanold lab

Precise Extraction of Neural Motifs Reveals Multiscale, Parallel Encoding Schemes in Auditory Cortex Neural population activity is often stereotyped into recurring activity patterns, i.e., neural motifs, which can be seen as the fundamental building blocks in sensory processing and cognition. In this...

New preprint out: in collaboration with Adam Charles (‪@baselesspursuit.bsky.social‬) Liang and Mingxuan show how single unit activity and neural motifs in A1 provide different information in parallel within the greater neural population. www.biorxiv.org/content/10.1...

Patchy harmonic functional connectivity of the mouse auditory cortex | PNAS Analyzing the functional connectivity of the brain is an enormous challenge, as deciphering functional connectivity requires knowledge of functiona...

New paper out! Peter, Sahar, and Anuthhara show that even though the frequency preference of neighboring neurons in A1 is functionally diverse, the functional connection patterns are functionally precise and harmonically related. Great collaboration with Babadi lab!
www.pnas.org/doi/10.1073/...

Brief periods of visual deprivation in adults increase performance on auditory tasks Behavioral neuroscience; Cellular neuroscience; Sensory neuroscience

New paper out: Our prior work had shown that adult visual deprivation can change circuits in the auditory cortex. Now Peter shows that temporary visual deprivation in adults can improve functional hearing and even attenuate age related high-frequency hearing loss: www.cell.com/iscience/ful...

New preprint that was a long time in the making: HiJee and Travis use in vivo holographic optogenetic stimulation to look at how ensembles in auditory cortex interact:

www.biorxiv.org/content/10.1...

#neuroscience 
#auditorycortex 
#optogenetics 
#Heaing

Whole-cortex in situ sequencing reveals input-dependent area identity - Nature BARseq interrogates the expression of 104 cell-type marker genes in 10.3 million cells over nine mouse forebrain hemispheres to reveal the role of peripheral inputs on cortical area development.

Fun to contribute to a collaborative paper with Xiaoyin Chen (Allen Institute), Jesse Gillis (Toronto), Stephan Fisher (Inst. Pasteur), and Tony Zador (CSHL).
www.nature.com/articles/s41...