Preschool musicality is associated with school-age communication abilities through genes related to rhythmicity. New paper by @luciadehoyos.bsky.social & al. with Ellen Verhoef, @profsimonfisher.bsky.social , @bstpourcain.bsky.social
doi.org/10.1038/s41539-025-00329-y
Our paper out today in @naturehumbehav.bsky.social integrates data from large-scale genome scans of dyslexia & rhythm skills, as a novel way to investigate biological overlaps between human traits related to language & musicality. Co-led by Reyna Gordon (Vanderbilt). 🧪
www.nature.com/articles/s41...
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I have been (foolishly?) searching for peak 2015-2017 twitter "science on socials" magic... In an experiment to recapture that excitement, I talked to @eikofried.bsky.social , in what might veer into podcast territory(?), about a new GWAS of Depression (N > 5 million) www.youtube.com/watch?v=vHvB...
And there you have it! #ExInPlotter, an easy-to-use online tool for plotting your genes of interest. Here applied in our latest CHD3 pre-print on bioRxiv (den Hoed et al). biorxiv.org/content/10.1...
@joerydh.bsky.social
Do you want to also plot additional custom sequences? (e.g. guideRNA, probes...) 🚩You can do that too! We provide an example file for this.
How does it work? ⚙️
1️⃣ Select the genome build (e.g. Human-hg38)
2️⃣ Write down the gene you want to visualise (e.g. CHD3)
3️⃣ Select as many transcripts as you would like to plot
4️⃣ Adapt the scale bar (in case your gene is bigger/smaller than the default one)
5️⃣ Export it as pdf
Looking for an online tool to plot your gene of interest? @joerydh.bsky.social and I have created #ExInPlotter. A shiny app where you can select a genome build (also non-human ones) and plot your gene(s) of interest.
Check it out here: jho2024.shinyapps.io/ExInPlotter/
A new publication from the EAGLE consortium: Genome-wide Analyses of Vocabulary Size in Infancy and Toddlerhood:
www.biologicalpsychiatryjournal.com/article/S000...
with summary statistics deposited here: t.co/5f0SFNf0mb
What makes us so susceptible to the power of music?
Our new pre-printed work suggests that genetic variation, primarily dissociated from other relevant perceptual-affective processes, also seems to be at play.
www.biorxiv.org/content/10.1...
But the story does not end here ...
🚨Our study "Structural models of genome-wide covariance identify multiple common dimensions in autism", where we disentangle phenotypic heterogeneity in ASD from a genetic perspective, is out now in Nature Communications
➡️ nature.com/articles/s41...
@bstpourcain.bsky.social @simonsfoundation.org
