WREXHAM LEAD CHELSEA IN THE FA CUP 😳
07.03.2026 18:07
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WREXHAM LEAD CHELSEA IN THE FA CUP 😳
38% of airline passengers vote to open plane door midflight because that bitch stewardess said not to
There's the data I want! obj@obj@obj@list$params
Me desperately trying to verify some small piece of information in my single cell object.
Excited to share this preprint that describes my latest work on using GPUs to accelerate processing of RNA-seq data.
The title says it all: "RNA-seq analysis in seconds using GPUs" now on biorxiv www.biorxiv.org/content/10.6... and github github.com/pachterlab/k...
Figure 1 shows they key result
Absolutely fantastic work!
I'm sorry, 50 what now?
"We present a GPU implementation of kallisto for RNA-seq transcript quantification (...). For a large dataset of 295 million reads, runtime drops from 40 minutes to 50 seconds"
www.biorxiv.org/content/10.6...
My school district is being forced to lay off several educators and a librarian because of a $500,000 budget gap, or roughly the amount spent on the war while I was typing this post.
Today we at @TPM are kicking off our Annual Membership Drive. If you're a TPM Reader and not a Member please consider signing up today.
If yr already a member, please retweet this post and this link. For something even more helpful continue in this thread ... talkingpointsmemo.com/edblog/i-nee...
After years of work, the centerpiece of my PhD is published in @natmethods.nature.com! Read it to learn about the biophysical insights we can get from single-cell data!
But first, I would like to talk a bit about RNA velocity and normalization. 1/
Weighted Gene Co-expression Network Analysis (WGCNA) has been the go to program for analysis of gene expression modules for nearly two decades but it is a difficult to implement. To make it easier to use WGCNA, I used Codex to build a human in the loop agentic workflow. github.com/lowrylab/WGC...
It is a wild reality that the difference between “Obama successfully negotiates the JCPOA“ and “Trump tears up JCPOA and orders obliteration from the skies without Congress having any idea what’s going on” is a contingent swing in ~2% of the electorate
A line graph showing NSF grant awards made through 2/27/26 for fiscal year 2026 compared with grant awards for fiscal years 2021-2025.
NSF Update (Awards through 2/27/26)
Directorates to follow
1/10
The first version of FigTree was released nearly 20 years ago and it is still widely used (including by me). But there are currently 85 issues on the GitHub repo (github.com/rambaut/figt...) and some of them I don’t really like the look of.
Trump's attacks on Iran are dangerously illegal and a mistake of staggering scale. Has he learned nothing from decades of U.S. military disaster in the Middle East? Has he spent not one single minute studying the lives lost and trillions wasted in Iraq and Afghanistan and Syria and Libya?
Amazing peppered moth story from Saccheri lab - same locus, but different structural variants, underly parallel evolution of industrial melanism in the UK and across continental Europe.
I don't think we should host the World Cup, tbh
During the Iraq war, I protested with certain knowledge that I was in the minority, going against majority opinion.
This is categorically not that.
Impeach and remove
This is murder. ICE routinely deposits released detainees far from their home just to be cruel. It’s standard practice. To do this to a blind man on a wet cold winter day in Buffalo is to know you are potentially sending him to his death.
Pipeline release! nf-core/rnaseq v3.23.0 - nf-core/rnaseq v3.23.0 - Gallium Gecko!
Please see the changelog: https://github.com/nf-core/rnaseq/releases/tag/3.23.0
Can't wait to release a 10-year-old birthday version for SeqKit!
- 10 years
- 2 papers, 3500 citations
- 20 contributors
- 40 subcommands
- 880 commits
- 500 issues
- 685.5K Bioconda total downloads
Thank you all, dear contributors and users!
I'll keep maintaining it.
github.com/shenwei356/s...
no quarter can or should be given to hold this evil to account
I just call it high throughput sequencing.
damn, Trump's surgeon general nominee Casey Means is a transparent bullshitter even by the standards of the regime. Watch how she's tries to blame Chris Murphy's staffers for the fact he has her dead to rights on being dishonest and corrupt.
Stony Brook University’s Institute for Advanced Computational Science (IACS) invites applications for a tenure-track Assistant Professor position in computational and physical sciences.
Come be my colleague!
apply.interfolio.com/181179
So I think it's fair to say that only a tiny, tiny percentage of the US population was tied up with Epstein. But weirdly maybe 70% of the people in the field of evolutionary psychology.
They're not sending their best. Or maybe they are.
