Jakub Harnos lab

So proud of my team.
Talented, hardworking, growing every day.
Being there for them is my biggest joy.

Harnos Lab 2026 🐸 😍 🥳

🐸 Amphibians take over Europe!!
📍 Prague. July 3–5, 2026.

The European Amphibian Conference 2026 is coming: 3 days of cutting-edge science, bold ideas, iconic speakers, and serious frog & axolotl energy ✨

👉 Register. Submit. Be there. Do not miss it.
amphib-conf2026.sciencesconf.org?lang=en

A new Master is born 🎓
Kristýna finished her Master’s degree in the Harnoš lab 🔬
Our fourth Master - congratulations 🚀

Welcome to Brno 🇨🇿
Our two new exchange students, Alba Macipe Feito and Ana Moreno Llorente 🇪🇸
They will study molecular and cell signalling for the following four months 🔬
Good luck and godspeed 🚀

Together with @harnoslab.bsky.social, we compiled what is known about direct interactions of Wnt and Notch components, and advanced the testable framework of how the crosstalk could allow for a more polarized cellular response to one pathway or the other.

Why do we lose so much talent in academia?
Let’s talk about it – openly, together, responsibly.

NEXT TUESDAY AT 5:30 PM.

PI Forum Brno #7 | Feb 3 @ CEITEC MU
For all PIs, PhDs & researchers in Brno.

Chaired by @fabianlab.bsky.social

Decoding ‘Wntch’: the intertwined Wnt and Notch pathways in development and disease Abstract. Multicellularity emerges from the ability of cells to undergo functional differentiation. One of the key mechanisms that enables this coordinatio

New Paper Alert!

1982: WNT discovered
1990s: NOTCH enters the stage
2000s: “Let’s study pathways separately.”
2025: “Actually, they talk to each other.”

Welcome to the era of WNT-NOTCH crosstalk

Great collaboration with Mašek lab (CZ) and G. Collu (US)

royalsocietypublishing.org/rsob/article...

When you urgently need the restroom but get lost in a Xenopus development poster instead… 🐸🧠
Thanks to my lab heroes Lorena & Douglas for representing the #DaysOfOpenDoors at Masaryk University
#frogpower #MUNI

🧪🐸 PhD position open in the Harnos Lab (Masaryk University, Brno)!
We study cell migration, WNT/PCP signaling, mitochondria & energy in Xenopus.
Start: June 2026 (flexible)
Apply by Feb 28, 2026
📩 harnos@sci.muni.cz

#PhDposition #CellBiology #Mitochondria #Xenopus #WNT #PCP

Just published a #BehindThePaper blog post about our new paper on PRICKLE3 and WNT/PCP signalling! 🧬 Check out the story behind the science and what we learned along the way 👇
communities.springernature.com/posts/behind...

With @fabianlab.bsky.social — first author and last author in their natural habitats. #IKEA_Biology #SameOffice_SameChallenges #Pat&Mat

Harnos Lab - Section of Animal Physiology and Immunology ——– What we work withWe study early Xenopus frog embryos: a powerful model for developmental biology. 🐸 Why frogsTheir embryos are large, develop outside the body, and are ideal for live imaging and e...

🚀 Check out the newly improved Harnos Lab webpages!

Our research on cell polarity, development, and migration - now with a fresh look.

👉 ueb1.sci.muni.cz/ofiz/en/harn...

#CellPolarity #DevelopmentalBiology #Xenopus #WntSignaling

🔥 New paper out!
PRICKLE3 is not just another PRICKLE.
It stabilizes VANGL, blocks CK1ε phosphorylation, suppresses RNF43, and rewires WNT/PCP signaling across species.
Big mechanism. Big fun. 🐸🔥
www.nature.com/articles/s42...

Milé @msmtcr,
když příště nebude sedět JEDNO číslo v Letter of Intent s hlavním projektem a celý projekt je kvůli tomu AUTOMATICKY vyřazen bez jakéhokoli upozornění, stačil by nám jeden krátký email k opravě.
Místo toho: žádné review, a měsíce či roky práce v pr... myslím pryč.

Merry Christmas from the Harnoš Lab 🎄🐸
See you in an exciting 2026! ✨

Thanks, Elias!!

Developmental toxicity of fluconazole and 1,2,4-triazole in Xenopus laevis - PubMed Fluconazole (FLU) is a widely used antifungal agent frequently detected in surface waters because of its extensive use in medicine, agriculture, and personal care products.Despite concerns about its persistence and developmental toxicity in aquatic species, its effects on amphibians remain poorly un …

New paper out in Sci Rep 🎉
Xenopus + azoles + developmental biology 🐸
A great collaboration with Veterinary University Brno.
Read it here: pubmed.ncbi.nlm.nih.gov/41350377/

Thanks, Peter!!!!!!

Thanks!!!!!!

🔥 BIG NEWS! 🔥

Thrilled to share that I have been selected as one of the MUNI Junior Star 2026 awardees! ⭐️

Huge congratulations to all fellow awardees — and thank you, MUNI, for this incredible opportunity! 🙌

Let’s make science shine. 💫

#MUNIJuniorStar #Science #Research #ProudMoment

Preparing for my big talk at the GAMU Annual Conference 2025!
Grateful for the opportunity to share our science and the achievements of the Harnoš Lab. Vamos! 🚀🐸

MAGA — Make AMPHIBIANS Great Again! 🐸
We just wrapped up the 2nd Czech Amphibian Friends meeting: great interactions, strong science, midnight swimming, and exciting collaborations ahead.
Big plans for 2026 — stay tuned!
Vladimir Krylov, we missed you!
Proud to help organize this event.

🤣🤣

Our PhD student Šárka is now giving a chalk-talk presentation on her Prickle and neurulation work in front of her fellow students — and she is doing great! Go, Šárka! 🐸💪
#MUNI #PhDretreat #Xenopus #frogpower

How do you make a group of scientists really busy?
Organize a scientific speed-dating session! Three minutes per pair — the clock is brutal.
Happy to host this one! 🔬⏱️😄
#PhDretreat #MUNI

Honored to give a talk about Xenopus at the prestigious IMG courses in Prague today! Excited to introduce this amazing frog model to new audiences. 🐸 #FrogPower

A proper hashtag#WoodstockBio2 welcome for @odedrechavi.bsky.social — complete with the YMCA song (yes, really 😄).
With @harnoslab.bsky.social we couldn’t resist celebrating a scientist who truly embodies fun and courage in science.
#science #FabianLAB, @paveltomancak.bsky.social 🙏

It’s fantastic to meet Oded Rechavi at my home institution! 🔥 Great chat about his work on the Dead Sea Scrolls, where his team used DNA analysis to reveal that some fragments came from different animals and regions — rewriting what we thought we knew about the oldest Bible. 📜🧬

Congrats, nice work!!! 👍

It’s my greatest pleasure to co-organize this event! 🚀

PIs from Brno: come join us and see what this supportive initiative is all about! 🙌

#BrnoScience #YoungPIs #Networking