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David R. Martinez

@davidmartinez

Assistant Professor of Immunobiology and Microbial Pathogenesis at Yale School of Medicine. Hanna H. Gray Faculty Fellow of the HHMI. Scientist. Husband/Dad. Viral pathogenesis. Vaccines. Immunobiology. Above all, be kind.

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28.09.2023
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Latest posts by David R. Martinez @davidmartinez

Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for th...

Wow. Harvard nuking its PhD programs

- Science PhD admissions reduced by more than 75%
- Arts & Humanities reduced by about 60%
- Social Sciences by 50–70%
- History by 60%
- Biology by 75%
- The German department will lose all PhD seats
- Sociology from six PhD students to zero

21.10.2025 17:11 πŸ‘ 2744 πŸ” 1503 πŸ’¬ 14 πŸ“Œ 504

The first locally acquired case of chikungunya in the US since 2019 has been reported on Long Island

16.10.2025 13:42 πŸ‘ 17 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1
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September Fellow's Spotlight on Dr. David Martinez Our September Fellows Spotlight goes to Keystone Symposia Fellow Dr. David Martinez of Yale Medical School who played a critical role in research and development of the COVID-19 vaccines and antibody ...

ICYMI: Our Sept Fellows Spotlight features Dr. David Martinez @davidmartinez.bsky.social (@yaleschoolofmed.bsky.social) and his work on #InfectiousDisease, #DengueVirus & #COVIDVaccines. Learn more + apply to be a #KSFellow! πŸ”— keypoint.keystonesymposia.org/home/septemb...

#KeystoneSymposia

09.10.2025 16:44 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Dear #microbiology and #immunology community- I took a break from social media after I deleted my Twitter account, but am back here. Please help me rebuild my community by following me and amplifying this message- I will follow you back. Thank you and I look forward to our many interactions!

05.10.2025 16:10 πŸ‘ 76 πŸ” 32 πŸ’¬ 5 πŸ“Œ 2
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Department of Microbiology | The University of Chicago

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

06.10.2025 17:32 πŸ‘ 19 πŸ” 26 πŸ’¬ 0 πŸ“Œ 0
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Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas Cheung et al. describe efficient T cell control of nascent neoantigen+ and nearby neoantigen-negative sarcoma cells, underlying a ∼50% reduction in tumor penetrance. This otherwise imperceptible immun...

Happy to announce the publication using advanced models to understand how T cells mediate efficient immunoediting in early sarcomas.

This was a collaboration between Julie Cheung and Brian Hunt
in the lab

Thanks to Cancer Cell for publishing our work.

www.cell.com/cancer-cell/...

02.10.2025 16:49 πŸ‘ 26 πŸ” 11 πŸ’¬ 2 πŸ“Œ 2
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Exclusive: NIH to dismiss dozens of grant reviewers to align with Trump priorities The move would undo years of work, leaving advisory councils understaffed, and without the full expertise needed for reviews.

NEW: In an unprecedented move, the NIH will soon disinvite dozens of scientists about to take positions on advisory councils that make final decisions on grant funding.

NIH staff were told to select others aligned with the Trump administration and told to expect placements by political appointees.

14.07.2025 23:25 πŸ‘ 1037 πŸ” 786 πŸ’¬ 46 πŸ“Œ 178

"No vaccine was tested more extensively than the RNA vaccines, and no vaccine was given to more people than the mRNA vaccines, & they were found to be incredibly safe...and effective. They saved 20 million lives, & they stopped a pandemic that was shutting down the world."
-Drew Weissman

20.09.2025 15:23 πŸ‘ 516 πŸ” 160 πŸ’¬ 5 πŸ“Œ 7

The problem with believing vaccines are dangerous is that by the time you realize you’re wrong, it’s too late and someone you love dies of a preventable disease.

Florida is about to find this out the hard way.

04.09.2025 20:15 πŸ‘ 240 πŸ” 67 πŸ’¬ 13 πŸ“Œ 2

RFK Jr. rolled out that old chestnut again about how healthy Americans were in the 60’s, so here’s a fact check.

In 1965:

-42% of American adults smoked; it’s 11% now.

-The infant morality rate was 24.7/1000; it’s 5.6/1000 now.

-Overall life expectancy was 70 years; it's about 77 years now.

04.09.2025 18:46 πŸ‘ 18499 πŸ” 6840 πŸ’¬ 747 πŸ“Œ 318

A bizarre dogma has emerged among the anti-mRNA crowd that the only data we have on vaccines is from the original trial papers, rather than the HUGE volume of studies that came out subsequently...

02.09.2025 20:35 πŸ‘ 164 πŸ” 47 πŸ’¬ 7 πŸ“Œ 5
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🚨New Paper in Cell πŸ§΅πŸ”Ž

Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox.

We were very excited (and lucky!) to contribute to this collab. effort.

πŸ¦ β€œHuman monoclonal antibodies targeting A35 protect from death caused by mpoxβ€πŸ¦ 
doi.org/10.1016/j.cell.2025.08.004

26.08.2025 15:55 πŸ‘ 26 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope Rao et al. demonstrate that convergent somatic hypermutations in the light chain, enriched within a sarbecovirus-specific public antibody clonotype, drive affinity maturation. This antibody targets a ...

🚨 New Publication!!!

I’m thrilled to share our latest study, β€œClonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”.
www.cell.com/cell-reports... [1/4]

12.08.2025 18:52 πŸ‘ 40 πŸ” 14 πŸ’¬ 3 πŸ“Œ 0
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Nature: Cancelling mRNA studies is the highest irresponsibility

go.nature.com/3HDx4wD

cc Jay Bhattacharya

15.08.2025 20:21 πŸ‘ 633 πŸ” 245 πŸ’¬ 10 πŸ“Œ 14
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Opinion | America Is Abandoning One of the Greatest Medical Breakthroughs

America Is Abandoning One of the Greatest Medical Breakthroughs www.nytimes.com/2025/08/18/o...

19.08.2025 01:04 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

To have this paper appear the same day that RFK Jr is canceling all mRNA vaccine funding is further indication that irony is not dead, even though we might all be soon.

06.08.2025 00:35 πŸ‘ 471 πŸ” 164 πŸ’¬ 15 πŸ“Œ 0
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Gunman in Deadly C.D.C. Shooting Fixated on Covid Vaccine, Officials Say

A 33-year-old ex-Marine police officer was shot at the CDC by someone who believed he was hurt by the Covid vaccine. The policeman was a father of two with another baby on the way --->

www.nytimes.com/2025/08/09/u...

09.08.2025 20:08 πŸ‘ 40 πŸ” 10 πŸ’¬ 3 πŸ“Œ 3
2025 Gilliam Fellows program announcement highlighting graduate student Celeste Robles from UNC Chapel Hill (advisor Helen Lazear)

2025 Gilliam Fellows program announcement highlighting graduate student Celeste Robles from UNC Chapel Hill (advisor Helen Lazear)

So proud of Celeste Robles @celeste-robles.bsky.social for being selected as a 2025 Gilliam Fellow! Thrilled to be joining the Gilliam community @hhmi.org
www.hhmi.org/programs/gil...

08.08.2025 17:56 πŸ‘ 21 πŸ” 6 πŸ’¬ 2 πŸ“Œ 0

Beaming with pride that Jordan Polster, a student in my lab at Yale, was selected for the #Gilliam #Fellowship from @hhmi.org

I look forward to mentoring Jordan and participating in the various mentorship workshops.

Jordan - congrats! And I can’t wait to see your research advance!

07.08.2025 15:02 πŸ‘ 19 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Congratulations 2025 Gilliam Fellows and Advisors! πŸŽ‰

The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments.
Through this program, HHMI supports both graduate students and their faculty thesis advisors.

07.08.2025 13:05 πŸ‘ 68 πŸ” 27 πŸ’¬ 3 πŸ“Œ 22
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Senate appropriators approve Labor-HHS bill with NIH bump The vote and lawmaker comments show that most senators aren't going along with the White House's proposed 40% budget cut to NIH.

BIG NEWS:

β€œSenate appropriators on Thursday approved an FY26 Labor-HHS bill that included a slight bump in funding for the NIH, with a strong 26–3 bipartisan vote.”

Thank you to members of the Senate Appropriations Committee on both sides of the aisle!

www.axios.com/pro/health-c...

31.07.2025 18:48 πŸ‘ 113 πŸ” 26 πŸ’¬ 2 πŸ“Œ 1

The NIH budget will INCREASE by $400 million β€” not slashed by 40%, as Trump proposed β€” according to a proposal by Senate appropriators, says Sen Murray.

"Some have asked if there will even be an NIH by [2029]. The commmittee's resounding message is yesβ€”Congress has your back", she says.

31.07.2025 13:53 πŸ‘ 260 πŸ” 78 πŸ’¬ 8 πŸ“Œ 14
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In preparation of today's mark-up of the NIH appropriations bill in the Senate and other activities, I sent this note to Senator Susan Collins' office.

1/2

31.07.2025 12:58 πŸ‘ 192 πŸ” 31 πŸ’¬ 11 πŸ“Œ 12

Extra kudos and thanks to all the staff at NIH and NSF and other federal funding agencies for working extra hard in very small windows of opportunity to get grants reviewed and funds released before the attention-addled federal policies change again (on an hourly basis).

30.07.2025 20:41 πŸ‘ 401 πŸ” 85 πŸ’¬ 3 πŸ“Œ 3
Brown University's campus. A headline reads: "Brown University Makes A Deal With the White House to Restore Funding." Photo credit: lan MacLellan for The New York Times.

Brown University's campus. A headline reads: "Brown University Makes A Deal With the White House to Restore Funding." Photo credit: lan MacLellan for The New York Times.

Breaking News: Brown University was said to have reached a deal with the Trump administration to restore federal funding. nyti.ms/459nQzY

30.07.2025 20:54 πŸ‘ 60 πŸ” 29 πŸ’¬ 57 πŸ“Œ 64

Reviewer #3 feedback.

23.07.2025 10:53 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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holy shit lmao

19.07.2025 03:21 πŸ‘ 26446 πŸ” 5013 πŸ’¬ 490 πŸ“Œ 711
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New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats @amankumar25.bsky.social, Robyn Tamblyn, and the rest of the team.

www.nature.com/articles/s41...

16.07.2025 19:59 πŸ‘ 14 πŸ” 6 πŸ’¬ 3 πŸ“Œ 1
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Macrophage-derived oncostatin M repairs the lung epithelial barrier during inflammatory damage Tissue repair programs must function alongside antiviral immunity to restore the lung epithelial barrier following infection. We found that macrophage-derived oncostatin M (OSM) counteracted the patho...

πŸŽ‰ Over the moon to share the first paper from my lab!! We discovered an unexpected role for the cytokine OSM in lung epithelial homeostasis and repair. 🧡 1/n www.science.org/doi/10.1126/...

11.07.2025 01:03 πŸ‘ 142 πŸ” 30 πŸ’¬ 12 πŸ“Œ 6
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Miss Rachel continues to have more of a moral backbone than 99% of public figures

10.07.2025 20:31 πŸ‘ 5343 πŸ” 1748 πŸ’¬ 48 πŸ“Œ 113