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Jorge Almagro

@jorgealmagro

LSRF postdoctoral fellow at @thefuchslab.bsky.social, Rockefeller Uni πŸ—½ | Cancer biology πŸ¦€ | Birds 🦩 | Progressivism & Union Power ✊🏼 | Free Palestine πŸ‡΅πŸ‡Έ | He/Him πŸ³οΈβ€πŸŒˆ

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07.11.2024
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Latest posts by Jorge Almagro @jorgealmagro

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It’s time to talk about epithelial geometry and cancer. How can the architecture of an epithelium affect how tumors will grow and spread? In this thread, @jorgealmagro.bsky.social

23.11.2025 08:01 πŸ‘ 50 πŸ” 19 πŸ’¬ 1 πŸ“Œ 3

Fascinating #EpithelialMechanics thread by @jorgealmagro.bsky.social, exploring the connection between tissue geometry and tumor growth πŸ‘‡

23.11.2025 08:31 πŸ‘ 14 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Yearly Fuchs lab picnic 🧺

17.06.2025 03:43 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury Novak et al. discover that dietary serine impacts whether hair follicle stem cells (HFSCs) prioritize hair growth or skin repair after injury. HFSCs gauge metabolic stress using the ISR and accelerate...

New paper alert! We report in @cp-cellmetabolism.bsky.social how serine regulates stem cell fate in physiology and upon wounding.
Good work, Jesse and collabs!
www.cell.com/cell-metabol...

12.06.2025 15:38 πŸ‘ 4 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Decenas de sociedades científicas piden a la Comunidad de Madrid que impida la destrucción del Museo Olavide Las instituciones recuerdan al Gobierno de Isabel Díaz Ayuso que la colección, una joya de la medicina expulsada por la Universidad Complutense, pertenece a una consejería. EL PAÍS graba los preparativos del traslado

Dos decenas de sociedades cientΓ­ficas han solicitado a la Comunidad de Madrid que impida urgentemente el β€œriesgo de destrucciΓ³n” del Museo Olavide, una joya de la historia de la medicina que incluye unas 700 figuras de cera de pacientes reales

11.06.2025 13:02 πŸ‘ 56 πŸ” 25 πŸ’¬ 2 πŸ“Œ 1
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It was heartwarming to join academic workers together in the fight against funding cuts, layoffs, and attacks to freedom of speech in our campuses. Scientists will not give up! @uaw.org

09.04.2025 14:59 πŸ‘ 7 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Los espaΓ±oles son los europeos menos preocupados por la seguridad y defensa, segΓΊn el EurobarΓ³metro La ΓΊltima encuesta de la UE subraya la importancia de mostrar β€œunidad” ante los desafΓ­os globales

β€œβ€¦EspaΓ±a, para cuyos ciudadanos la prioridad mΓ‘xima debe ser la educaciΓ³n e investigaciΓ³n (40%, frente al 23% de media europea), mientras que la defensa cae al 20%”
elpais.com/internaciona...

25.03.2025 13:06 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Submitting my PhD paper after 7.5 years 🫣

23.03.2025 00:51 πŸ‘ 77 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Moby-Dick review β€” the Met sets sail with Jake Heggie’s sprawling epic The opera β€” newly staged in its Metropolitan Opera premiere β€” is as ambitious and frustrating as its source material

My thoughts on Heggie’s Moby-Dick at the Met, for @thetimes.com

www.thetimes.com/culture/clas...

04.03.2025 13:08 πŸ‘ 9 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Postdocs vs students @thefuchslab.bsky.social laser tag was barely a competition 😏

01.03.2025 12:47 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Yesterday we marched to oppose the hijacking of the NIH and the government by a nazi oligarch. Hands off the NIH!! No research, no cures ✊🏼

20.02.2025 19:28 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Great news! @greatysp.bsky.social @jorgealmagro.bsky.social

11.02.2025 14:29 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Congratulations to @jorgealmagro.bsky.social and @thefuchslab.bsky.social as well!! πŸŽŠπŸŽ‰πŸ₯³πŸ₯³ @rockefelleruniv.bsky.social @hhmi.bsky.social

11.02.2025 14:27 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

New #Review! πŸ₯³

@jorgealmagro.bsky.social, @thefuchslab.bsky.social et al. discuss the role of stem cell mechanics during developmental processes and what happens when the mechanics of the stem cell niche are disrupted in cancer.

πŸ‘‰ go.nature.com/3EsJzJx

#StemCells #Mechanobiology #Cancer

05.02.2025 10:33 πŸ‘ 9 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Shaping epithelial tissues by stem cell mechanics in development and cancer Nature Reviews Molecular Cell Biology, Published online: 29 January 2025; doi:10.1038/s41580-024-00821-0Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of…
29.01.2025 10:52 πŸ‘ 12 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

Very happy to see our review out in @natrevmcb.bsky.social!
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here πŸ‘‡
www.nature.com/articles/s41...

29.01.2025 17:08 πŸ‘ 48 πŸ” 12 πŸ’¬ 0 πŸ“Œ 3
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Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...

Our first 2025 paper!
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social πŸ‘
www.nature.com/articles/s41...

29.01.2025 17:00 πŸ‘ 90 πŸ” 26 πŸ’¬ 3 πŸ“Œ 3
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Paper of the Week! Norepinephrine oscillation during sleep regulates blood/CSF flow and waste clearance
With @kevinng.bsky.social @fesubtil.bsky.social @rysazaman.bsky.social
www.cell.com/cell/abstrac...

16.01.2025 15:34 πŸ‘ 7 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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What an exciting read 😍

15.01.2025 23:26 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The Caltech and JPL Disaster Relief Fund

Caltech has set up a disaster relief fund for Caltech and Jet Propulsion Lab community members affected by the fires. Many lived in Altadena, which has been very heavily damaged. Please consider giving.
giving.caltech.edu/areas-to-sup...

13.01.2025 00:17 πŸ‘ 13 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1
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Reading a textbook may give answers to such essential questions πŸ˜…
From Kandel et al. β€œPrinciples of Neural Science” (5th edition, before Piezo was identified as the master mechanosensor)

10.01.2025 14:35 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The Vienna BioCenter Summer School 2025 call is now open for applications from talented undergrads. It is the perfect preparation for students who are interested in graduate study in the life sciences arena. 9-week research project, accommodation and stipend for successful candidates.

10.01.2025 11:15 πŸ‘ 6 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Kicking off 2025 Paper of the Week with @kevinng.bsky.social & @fesubtil.bsky.social. Today we discussed our friend @martinaparigi.bsky.social et al. recent paper in @nature.com. How do epithelia unlink necessary drivers of regeneration from malignant transformation?
www.nature.com/articles/s41...

09.01.2025 20:37 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Congratulations Jimmy and @paigearnold.bsky.social πŸ‘πŸΌ

08.01.2025 16:51 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Birding (and lynxing🀞🏼) with @atalavera.bsky.social somewhere in La Mancha…

02.01.2025 15:18 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Aida review β€” the Met’s tacky show is like a night in a Luxor casino Angel Blue’s impassioned singing as the heroine of Verdi’s opera is the highlight of a dispiriting night at the Metropolitan Opera in New York

My first review of 2025 - Michael Mayer’s new Aida at the Met, for @thetimes.com

www.thetimes.com/culture/clas...

01.01.2025 12:53 πŸ‘ 16 πŸ” 1 πŸ’¬ 6 πŸ“Œ 3
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Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic ...

Cancers may arise in tissues with a low mutational burden. It’s up to the microenvironment! We discussed this in @natrevcancer.bsky.social
www.nature.com/articles/s41...

31.12.2024 13:43 πŸ‘ 26 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0

2024 was a year of exciting discoveries and scientific discussions! A thread πŸͺ‘ of this years’ publications from our lab πŸ‘‡πŸΌ

31.12.2024 13:43 πŸ‘ 11 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

The Fuchs lab is now on Bsky and wishes you happy holidays!! πŸŽ„

18.12.2024 14:41 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Nobel Laureates Urge Senate to Turn Down Kennedy’s Nomination Elevating Mr. Kennedy to secretary of H.H.S. β€œwould put the public’s health in jeopardy,” more than 75 laureates wrote.

More than 75 Nobel Prize winners have signed a letter urging senators not to confirm RFK Jr.

The letter marks the first time in recent memory that Nobel laureates have banded together against a Cabinet choice. But Kennedy is a threat they could not ignore, one said. www.nytimes.com/2024/12/09/h...

09.12.2024 21:40 πŸ‘ 27922 πŸ” 8073 πŸ’¬ 771 πŸ“Œ 379