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MVLS Shared Research Facilities

@mvls-srf

Core Facility within @uofgmvls.bsky.social for Next Generation Sequencing | Mass Spectrometry | Protein Characterisation | Microscopy | Flow Cytometry | 7T MRI | Total Body PET | Research Software Engineering | Data Analytics @uofglasgow.bsky.social

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21.02.2025
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Latest posts by MVLS Shared Research Facilities @mvls-srf

Inside the Rewarding Brain | Neuroimaging Research with 7 Tesla MRI | University of Glasgow
Inside the Rewarding Brain | Neuroimaging Research with 7 Tesla MRI | University of Glasgow YouTube video by UofG MVLS

Here's a a video from @uofgmvls.bsky.social highlighting a simultaneous EEG and 7T fMRI neuroimaging study conducted at ICE that was recently published in @currentbiology.bsky.social

πŸ‘€ youtu.be/UzVbv8_ieJA?...
πŸ“– www.cell.com/current-biol...
🌐 www.gla.ac.uk/colleges/mvl...

10.03.2026 16:59 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Photograph of the SRF Exhibitor stall.  A white table cloth with technique and expertise postcards, pens, notebooks and mugs.  There is a red pop-up poster in the background.

Photograph of the SRF Exhibitor stall. A white table cloth with technique and expertise postcards, pens, notebooks and mugs. There is a red pop-up poster in the background.

We’re at the #IBioIC Conference 2026 in Glasgow today!

Great to see so many people working on biotechnology and bio-based innovation in one place. Looking forward to some inspiring talks and conversations.

Come say hi if you’re here πŸ‘‹
@uofgmvls.bsky.social #biotech

10.03.2026 09:58 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
University of Glasgow - Colleges - College of Medical, Veterinary & Life Sciences - Shared Research Facilities

We are excited to be heading to the IBioIC Conference on 10–11 March! πŸŽ‰

We’ll be up on Level 3 (Stand 3)! Come say hi, have a chat, and hear what the SRF team have been working on.

Looking forward to connecting with everyone πŸ‘‹

🌐gla.ac.uk/colleges/mvls/shared-research-facilities/

09.03.2026 10:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Fantastic to see this research published! Congratulations to the team from SIPBS @unistrathclyde.bsky.social Proud our facilities supported this work! #cancer #microfulidics #electronmicroscopy
www.mdpi.com/1999-4923/18...

www.gla.ac.uk/colleges/mvl...

05.03.2026 11:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Iain from Research Software Engineering is hosting a webinar on 24th March at 1200!
He will discuss how his team in the SRF supports quality in computational research
To sign up: forms.office.com/pages/respon...

04.03.2026 19:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

The SRF works closely with @uofgmvls.bsky.social & the wider community to help our wildlife. Whether this is building digital twins for ecosystems or #modelling to help prevent the spread of animal disease, we're here to raise awareness on #WorldWildlifeDay #WWD2026
www.gla.ac.uk/colleges/mvl...

03.03.2026 09:50 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Interdisciplinary research starts with knowing what’s possible. Here’s a visual guide to how our expertise and technologies can support broad, creative, hypothesis‑driven science. #protein #stress #biomarkers @uofgmvls.bsky.social

27.02.2026 07:22 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Whole Body Imaging Webinar | Shared Research Facilities at the University of Glasgow
Whole Body Imaging Webinar | Shared Research Facilities at the University of Glasgow YouTube video by UofG MVLS

Grab a cuppa and sit down to hear from Kristin about the amazing pre-clinical and clinical imaging facilities available at @uofgmvls.bsky.social @uofgpsychneuro.bsky.social @uofgcancersciences.bsky.social @royalmicrosoc.bsky.social #UK-PIN
www.youtube.com/watch?v=8zQM...

20.02.2026 12:03 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Research Assistant We have an exciting opportunity for a Research Assistant to contribute to multiple veterinary parasitology projects, working with Professor James Cotton and Dr Roz Laing. The successful candidate w...

Roz Laing and I are looking for a combined lab manager/(PD)RA to contribute to ongoing projects in the lab: initially for 18 months but hopefully a longer-term post, subject to funding. Closing date is 23 March. Please get in touch if you have any questions about the role.

tinyurl.com/246m632j

19.02.2026 19:13 πŸ‘ 1 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

This is on Tuesday 24th, scan the QR code or follow the link below to sign up! Sit with your lunch and learn about how the IPA can support your research and train you on their instrumentation. @uofgscmh.bsky.social @uofgengineering.bsky.social @uofgmvls.bsky.social @uofgcancersciences.bsky.social

20.02.2026 08:18 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

From idea to impact! This paper from @sbohvm.gla.ac.uk and @uofgsii.bsky.social shows what’s possible with electron microscopy
πŸ‘‰ www.gla.ac.uk/colleges/mvl...
Congratulations to the team! www.pnas.org/doi/abs/10.1... @pnas.org

18.02.2026 11:40 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

These women exemplify the curiosity, innovation, and leadership that make science thrive.
Here’s to celebrating and supporting every woman and girl pursuing a future in STEM. #February11

11.02.2026 16:16 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Data Analytics are honouring Prof Maria Fasli @sussex.ac.uk for Women In Science Day. A leader in AI and data science, she founded the Institute for Analytics& Data Science and was the first UNESCO Chair in the field. Her work spans prediction models in health & beyond. #February11

11.02.2026 16:16 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

For Women In Science Day, Cellular Analysis chose Dr Anne Carpenter @broadinstitute.org .Β  A pioneer of image‑based profiling, her open‑source tools like CellProfiler and Cell Painting assay have transformed drug discovery and empowered thousands of researchers worldwide. #February11

11.02.2026 16:14 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Whole Body Imaging is celebrating Women In Science Day with Prof Fiona Gilbert @cam.ac.uk, a leader in breast imaging and a pioneer in applying AI to cancer screening.Β  From Glasgow to Cambridge, her work is transforming radiology and improving early diagnosis.Β  #February11

11.02.2026 11:09 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Integrated Protein Analysis selected Prof Alice Pyne @sheffielduni.bsky.social for Women In Science Day.Β A UKRI Future Leader Fellow, she develops cutting‑edge AFM technologies revealing DNA structure at sub‑molecular scale. Β Her work is reshaping what’s possible in biophysics. #February11

11.02.2026 10:35 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

To mark Women In Science Day #February11, the Mass Spec team chose Dr Natalie Homer, Deputy Director of the Mass Spectrometry Core @edinburgh-uni.bsky.social. Natalie pioneers innovative LC‑MS/GC‑MS methods to study steroids and other small molecules and is a champion for technician careers!

11.02.2026 08:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

To celebrate Women & Girls In Science #February11, we've been discussing inspiring women whose work drives discovery across disciplines. Here are some exceptional scientists chosen by our teams and why they stand out.πŸ’ͺ♀️ @uofgmvls.bsky.social

11.02.2026 08:47 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

NEW PAPER ALERT! 🧲🧠✨
πŸ‘‰ Real-time multislice-to-volume motion correction for task-based EPI-fMRI at 7 T
πŸ”—https://www.sciencedirect.com/science/article/abs/pii/S0730725X25002383?via%3Dihub
@uofgmvls.bsky.social
#AdvancedDiagnostics&Therapeutics

06.02.2026 10:58 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
University of Glasgow - Colleges - College of Medical, Veterinary & Life Sciences - Shared Research Facilities

We’re thrilled to have showcased a glimpse of the groundbreaking research we’ve been proud to support in these areas! #WorldCancerDay @uofgmvls.bsky.social
Get in touch if you think we can support you with your research: www.gla.ac.uk/colleges/mvl...

04.02.2026 20:09 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Inhibition of ATR opposes glioblastoma invasion through disruption of cytoskeletal networks and integrin internalization via macropinocytosis AbstractBackground. Glioblastomas have highly infiltrative growth patterns that contribute to recurrence and poor survival. Despite infiltration being a cr

Using IF, confocal & timelapse super-resolution microscopy, the team supported work to show that ATR regulates actin & microtubule networks to increase the motility &infiltration of glioblastoma cells doi.org/10.1093/neuo... #WorldCancerDay @uofgmvls.bsky.social

04.02.2026 19:23 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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A one-base therapeutic insertion in the HBG2 distal promoter reactivates Ξ³-globin expression - Experimental Hematology & Oncology Background The reactivation of developmental silenced Ξ³-globin genes (HBG1/2) has shown promise as a therapeutic strategy for improving symptoms of Ξ²-hemoglobinopathies. Currently, the focus of therap...

A single-nucleotide insertion in the HBG2 promoter has shown the potential to significantly enhance Ξ³ globin expression. Our team contributed RNAseq expertise to this important discovery!! link.springer.com/article/10.1... #WorldCancerDay @uofgmvls.bsky.social

04.02.2026 17:53 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Susan's fundraiser for Little Princess Trust Help Susan Kitson raise money to support Little Princess Trust

Cancer isn’t just something we study, it’s something that affects real lives. This #WorldCancerDay, our colleague is donating her hair to the @littleprincesses.bsky.social to help children facing cancer. We’re incredibly proud!
You too can help children affected: www.justgiving.com/page/susan-k...

04.02.2026 17:14 πŸ‘ 4 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Co-inhibition of TGF-Ξ² and PD-L1 pathways in a metastatic colorectal cancer mouse model triggers interferon responses, innate cells and T cells, alongside metabolic changes and tumor resistance Colorectal cancer (CRC) is the third most prevalent cancer worldwide with a high mortality rate (20–30%), especially due to metastasis to adjacent organs. Clinical responses to chemotherapy, radiat...

By blocking TGF Ξ² & PD L1 pathways, researchers observed enhanced T cell infiltration and innate immune activation in colorectal cancer. We contributed flow cytometry and histology to characterise these complex responses. www.tandfonline.com/doi/full/10.... #WorldCancerDay @uofgmvls.bsky.social

04.02.2026 16:47 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Tuning ubiquitin transfer by RING E3 ubiquitin ligases through the linchpin residue RING family ubiquitin ligases (E3s) employ the RING domain to recruit the E2 thioester ubiquitin (E2∼Ub) intermediate to catalyze the transfer of ubiquitin (Ub) to substrates. A cationic Arg linchpin ...

We worked with Danny Huang from @cruk_si to study cancer-linked linchpin mutations affecting protein ubiquitination. Proteins were analysed with Xray crystallography & NMR to reveal how binding changes activity. doi.org/10.26508/lsa... @lsajournal.org #WorldCancerDay @uofgmvls.bsky.social

04.02.2026 15:58 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function Protein transfer through matrix-bound vesicles from CAFs enhances monocyte adhesion to endothelial cells.

Cancer-associated fibroblasts send vesicles that shape blood vessels and immune responses, aiding tumour growth. We provided electron microscopy to capture these detailed mechanisms. www.science.org/doi/epdf/10.... #WorldCancerDay @uofgmvls.bsky.social

04.02.2026 14:56 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

However, we can’t cure diseases we don’t understand, which is why our facility supports scientists around the world who are working to uncover the complex biology of cancer so this can be used to help save even more lives!

04.02.2026 14:06 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

High-quality scientific research has enhanced our understanding of cancer immensely over the past few decades, and resulted in huge improvements in the treatment and outcomes of these diseases. #WorldCancerDay
@uofgcancersciences.bsky.social @uofgmvls.bsky.social @cruk-si.bsky.social

04.02.2026 14:06 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Redirecting

This publication doi.org/10.1016/j.ip... shows the benefits of 7T vs 3T MRI in oligodendroglioma research! 7T MRI is a powerful tool for researchers, enabling better measurement and characterisation of brain tumours to inform more effective treatments. @uofgmvls.bsky.social #WorldCancerDay

04.02.2026 13:17 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos - British Journal of Cancer British Journal of Cancer - Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

We’re proud to support discoveries showing how ARID1A loss accelerates tumourigenesis through advanced RNAseq performed in our facility. This provides insight into aggressive prostate cancer biology &helps inform future strategies: www.nature.com/articles/s41...
#WorldCancerDay @uofgmvls.bsky.social

04.02.2026 11:53 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0