Meghna Chatterjee

Here we show that transmitting the Microbiome can transfer a host trait, independently of selection on the host genome. In mice, with selection for low activity levels. Correlates with levels of lactobacilli and indolelactate: transferring these alone also reduces activity.

Timescales in Cell Biology

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics - Nature Microbiology Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. This study presents an approach to systematically discover and ...

Excited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...

Call for expressions of interest for post doc positions in various locations worldwide to genetically engineer methanogens. The letterhead includes a large brown cow.

Honored to be part of a collaborative team receiving funding to genetically engineer methanogens in ruminants for reducing carbon emissions. We're now seeking multiple postdocs in the USA, Germany, and New Zealand - apply via the link!

docs.google.com/forms/d/e/1F...

🧫🧪 #ArchaeaSky #MicrobiomeSky

This is a nice longitudinal metagenomic analysis of CRISPR dynamics in the gut with a lot of cool findings, including showing clearance of MGEs after spacer acquisition:

Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome
www.biorxiv.org/content/10.1...

IMG/PR: a database of plasmids from genomes and metagenomes with rich annotations and metadata Abstract. Plasmids are mobile genetic elements found in many clades of Archaea and Bacteria. They drive horizontal gene transfer, impacting ecological and evolu

IMG/PR: a database of plasmids from genomes and metagenomes with rich annotations and metadata academic.oup.com/nar/advance-... #jcampubs

🚨 #DataVisualization in R for Scientists! 🔥

#DataViz protocols: An introduction to data visualization protocols for wet lab scientists#

A fantastic resource from @joachimgoedhart.bsky.social 🙏👏👍

joachimgoedhart.github.io/DataViz-prot...

🦠 Minimal Membranes for Minimal Cells 🦠! In our latest preprint, we introduce an approach to minimize and tune lipidome composition in mycoplasma and the Minimal Cell JCVI-Syn3A. tinyurl.com/53235uzt #Lipidtime @jcvi.bsky.social

Presented my first poster as a PhD student at the CMFI Symposium in Tübingen 🎉
3 days of very interesting scientific talks and great conversation.
Shout-out to @jmarsh.bsky.social for being my biggest support and an awesome supervisor!
🦠

Relative abundance data can misrepresent heritability of the microbiome - Microbiome Background Host genetics can shape microbiome composition, but to what extent it does, remains unclear. Like any other complex trait, this important question can be addressed by estimating the heritab...

Important paper about microbiome heritability (or lack thereof) by the Metcalf lab, h/t @phylogenomics.bsky.social microbiomejournal.biomedcentral.com/articles/10....

Just 12 days until the CMFI symposium in Tübingen! Check it out at cmfi23.com - speakers include Fredrik Bäckhed, Michael Fischbach, Carmen Buchenrieser, Eric Pamer, Michael Otto, and local speakers too, such as the wonderful Lisa Maier! October 11-13 🧫🦠

Time will tell haha

All set to bluskiii!