Pierpaolo Sorrentino's Avatar

Pierpaolo Sorrentino

@pierpasorre

I am a Neurologist and an Engineer, mainly using systems neuroscience applied to Neurological diseases. I am a tenured Associate Professor, working at Aix-Marseille university & Sassari university.

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30.11.2024
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Latest posts by Pierpaolo Sorrentino @pierpasorre

Redirecting

🧠 Real-world diagnosis β‰  case vs controls! Can MEG distinguish multiple diseases at once? Turns out a small set of phase-based connectivity edges can separate #MS, #ALS, #PD, and #MCI! @mconstancecorsi.bsky.social @inserm.fr @univ-amu.fr @univparissaclay.bsky.social

πŸ”— doi.org/10.1016/j.he...

09.03.2026 19:33 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

In case you missed it, I made a feed that uses a locally hosted LLM to sort through the entire Bluesky firehose to find great science. Topics span all cognitive science and neuroscience. Check it out! bsky.app/profile/did:...

05.03.2026 12:45 πŸ‘ 24 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0
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🀎

20.02.2026 08:59 πŸ‘ 720 πŸ” 187 πŸ’¬ 8 πŸ“Œ 9
Bruce Springsteen - Streets Of Minneapolis (Official Audio)
Bruce Springsteen - Streets Of Minneapolis (Official Audio) YouTube video by Bruce Springsteen

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.

Stay free

28.01.2026 17:02 πŸ‘ 97503 πŸ” 40888 πŸ’¬ 4302 πŸ“Œ 5362
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β€œThe longer I live, the more convinced I am that this planet is used by other planets as a lunatic asylum.”

- George Bernard Shaw

23.12.2025 04:47 πŸ‘ 2574 πŸ” 473 πŸ’¬ 52 πŸ“Œ 22
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Point of no returns: researchers are crossing a threshold in the fight for funding With so little money to go round, the costs of competing for grants can exceed what the grants are worth. When that happens, nobody wins.

"How can funders avoid crossing the Szilard point?"

The Szilard point is "the threshold at which the total cost of competing for a grant equals (or surpasses) the value of the available funding."

19.12.2025 07:57 πŸ‘ 112 πŸ” 59 πŸ’¬ 4 πŸ“Œ 16
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New preprint out!
How does criticality propagate from local neuronal circuits to whole-brain dynamics?
We tackle this with a multiscale, connectome-based mouse model @ldallap.bsky.social . 🧡/n
πŸ‘‰ biorxiv.org/content/10.6...

17.12.2025 10:59 πŸ‘ 14 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1

Big thanks to the solid team
@ldallap.bsky.social, @pierpasorre.bsky.social, @mnpompili.bsky.social, Pietro Bozzo, Bach Nguyen, Tomoki Fukai, Damien Depannemaecker, Leonardo Gollo

17.12.2025 10:59 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Neural Encoding of Symbolic, Non-Symbolic, and Embodied Non-Symbolic Numerical Information in Young and Older Adults Numeracy has important implications across the lifespan, and age-related decline represents a vulnerability for older adults managing daily tasks, yet underlyin

We started this research project almost for fun, and now it's a preprint!!!

ssrn.com/abstract=585...

#neuroscience #neuroskyence

05.12.2025 21:20 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Time, space, memory and brain–body rhythms - Nature Reviews Neuroscience Understanding how the brain represents experienced time and how representations of space and time are integrated to form episodic memories has been a goal of much neuroscientific research. In this Per...

Time, space, memory and brain–body rhythms
www.nature.com/articles/s41...
#neuroscience

22.11.2025 19:46 πŸ‘ 42 πŸ” 17 πŸ’¬ 0 πŸ“Œ 0
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Stop by this afternoon to chat about community structure in the πŸͺ°connectome!

πŸ“ZZ2/PSTR368.03

18.11.2025 16:39 πŸ‘ 14 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

With deep gratitude to my extraordinary co-authors @MariannaAngiolelli, @FukaiTomoki, @GustavoDeco, @pierpasorre.bsky.social, and @davemomi.bsky.social
β€”this work would not have been possible without them.
Supported by the MSCA grant @ec.europa.eu and @upf.eduβ€”more to come!

22.09.2025 09:02 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
https://ohbm-environment.org/ohbm-satellite-event/

https://ohbm-environment.org/ohbm-satellite-event/

🧠 Join us for the Brain Models for Multimodal Integration Symposium!
πŸ“… 12 September 2025 | ⏰ 12:00–13:15 UTC | 🌐 Virtual Event

Thrilled to co-chair w/ @pierpasorre.bsky.social at the @ohbmofficial.bsky.social Satellite Meeting! Feat. D. Depannemaecker & @gianmarcoduma.bsky.social ma.bsky.social.

05.09.2025 15:20 πŸ‘ 5 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0

Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.

We're very happy to announce that we are able to reduce the APC to $1400.

Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.

05.09.2025 02:59 πŸ‘ 233 πŸ” 80 πŸ’¬ 2 πŸ“Œ 6
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Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs Motor imagery-based Brain-Computer Interfaces (BCIs) restore control in persons with motor impairments, but up to 30% of users struggleβ€”a phenomenon known as β€œBCI inefficiency”. This study tackles a k...

πŸ“’ Preprint alert! πŸ§ πŸ’‘

Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs

πŸ”— www.biorxiv.org/content/10.1...

A great work led by Camilla Mannino w/ @pierpasorre.bsky.social & @neurodynamicslab.bsky.social! @nerv-lab.bsky.social @institutducerveau.bsky.social 🧡

27.08.2025 10:55 πŸ‘ 8 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
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Brain Fluidity as a Functional Marker of Tau-Related Neurodegeneration in Alzheimer’s Disease Alzheimer’s Disease (AD) is the most common form of dementia and one of the leading neurodegenerative disorders worldwide. Neurophysiopathologically, AD is characterized by neuronal death, accompanied...

🧠 New Preprint out!
Brain fluidity: a functional marker of neuronal death in Alzheimer’s disease (AD).
Our results highlight the link between dynamic brain connectivity disruptions and neurodegeneration in AD.
@pierpasorre.bsky.social @gianmarcoduma.bsky.social www.medrxiv.org/content/10.1...

23.07.2025 10:34 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Beta burst waveforms in PD! We find that specific types of beta bursts are rate-modulated by l-dopa, and STN-cortical connectivity during these burst types is related to clinical improvement. Fantastic work by Hasnae Agouram with @pierpasorre.bsky.social πŸ§ πŸ“ˆ

23.07.2025 05:26 πŸ‘ 14 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
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Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social

15.07.2025 14:05 πŸ‘ 214 πŸ” 83 πŸ’¬ 2 πŸ“Œ 11
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Variations in neuronal selectivity create efficient representational geometries for perception Our visual capabilities depend on neural response properties in visual areas of our brains. Neurons exhibit a wide variety of selective response properties, but the reasons for this diversity are unkn...

In many brain areas, neuronal tuning is heterogeneous. But how does this diversity help behavior? We show how tuning diversity shapes representational geometry and boosts coding efficiency for perception in our new preprint: www.biorxiv.org/content/10.1...
(w/ @sueyeonchung.bsky.social&Tony Movshon)

29.06.2025 00:19 πŸ‘ 75 πŸ” 20 πŸ’¬ 1 πŸ“Œ 3
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🧠 Want to understand how different higher-order methods compare in brain connectivity analysis?

Check out our new preprint β€” a fantastic collab with past & present NPL members @lordgrilo.bsky.social :
πŸ”— www.biorxiv.org/content/10.1...
A thread🧡

27.06.2025 07:47 πŸ‘ 17 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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Congratulations to Marie-Constance Corsi recipient of this year’s Early Career Award! Dr. Corsi’s innovative work in the #BCI field is already making a big impact.

06.05.2025 19:38 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2
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A new computer model of Parkinson's disease has been created by researchers in France and Italy and tested in a first small-scale patient trial.

Read more: www.ebrains.eu/news-and-eve...

27.05.2025 09:10 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
rt_neurocomp - rΓ©seau franΓ§ais de neurosciences computationnelles - subscribe

Researchers in France are working on creating a french network of researchers to organize interaction, communication and training in #Computational_Neuroscience. If you are a CompNeuro working in France, consider joining, and registering to our mailing list: listes.services.cnrs.fr/wws/subscrib...

02.05.2025 12:03 πŸ‘ 23 πŸ” 15 πŸ’¬ 2 πŸ“Œ 1
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Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus

Short-term sleep deprivation shows a distinct picture, affecting the thalamus

jamanetwork.com/journals/jam...

24.04.2025 20:42 πŸ‘ 24 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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How do local brain perturbations affect global processes?
doi.org/10.1073/pnas...
#neuroscience

21.04.2025 16:21 πŸ‘ 30 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Mapping global brain reconfigurations following local targeted manipulations | PNAS Understanding how localized brain interventions influence whole-brain dynamics is essential for deciphering neural function and designing therapeut...

After a long journey, our paper is officially out in PNAS! πŸš€ Huge thanks to the team β€” excited to finally share it with the world. Check it out: www.pnas.org/doi/10.1073/...

19.04.2025 16:27 πŸ‘ 15 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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Chaos in the Brickyard

sometimes this is what neuroimaging feels like: www.science.org/doi/abs/10.1...

11.04.2025 18:48 πŸ‘ 21 πŸ” 4 πŸ’¬ 2 πŸ“Œ 0
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Open source is draining.

One's todo-list is open to world.

People seldom realize the cost of what they get for free.

Unpleasant comments do happen.

Cost of maintenance is not understood.
opensource.com/article/17/2...

22.03.2025 15:53 πŸ‘ 70 πŸ” 18 πŸ’¬ 3 πŸ“Œ 1
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🧡 How do psychedelics shape brain activity?

Our new paper presents the largest neuroimaging study of psilocybin to dateβ€”revealing how context structures psychedelic brain states.

Title: Psychedelics Align Brain Activity with Context
Paper: lnkd.in/gt-kMR6d

A thread πŸ§΅πŸ‘‡ 1/n

17.03.2025 11:29 πŸ‘ 84 πŸ” 40 πŸ’¬ 4 πŸ“Œ 6

137 scientists from around the globe already signed up, what are you waiting for?

14.03.2025 13:58 πŸ‘ 16 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0