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Zhikai Liang

@shanwai1234

Assistant professor @NDSU; Computational biologist πŸŒ½πŸ«›πŸ«˜πŸ»β„οΈπŸ”₯β˜€οΈπŸͺ΄πŸŒΎ https://sites.google.com/ndsu.edu/lianglabndsu/home

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20.11.2024
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Latest posts by Zhikai Liang @shanwai1234

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Happy to see my PhD student π…πšπ‘πšπ π‡πšπ¬πšπ§ presenting one of his research projects at @ndepscor.bsky.social annual conference just since he officially started 3 months in the lab!

21.10.2025 20:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Plant cells are totipotent, meaning individual cells have the potential to develop into a full organism, a property unique to the zygote for animals. However, in most species for most cells, plant cells are not spontaneously totipotent, since they must be treated with specific hormone combinations to unlock their totipotency. Species within the Kalanchoe genus is unique as they spontaneously develop foliar embryos that are fully realized plantlets with shoot and root from notches along the edges of leaves. We speculate that the progenitor cells that give rise to these foliar embryos are totipotent, and we are using single cell techniques to identify & characterize them. In addition to being a fundamental process for plant biology, we foresee unlocking totipotency has many biotechnological applications, such as faciliating genetic transformation and the development of synthetic organs of biomanufacturing.

Please share! I'm looking for a postdoc. The position is to lead one of the following projects: 1) regulation of plant specialized metabolism by cell fate, or 2) foliar embryogenesis in the succulent plant Kalanchoe.

Learn more abt projects: cxli233.github.io/cxLi_lab/res...

04.09.2025 14:00 πŸ‘ 88 πŸ” 110 πŸ’¬ 1 πŸ“Œ 3

What's the difference between dominance and epistasis? Two physically distinct mutations in a gene interact such that the het is identical to one of the homozygotes. If I define the gene as a locus, we call this dominance. If I define each bp as a locus, we call this epistasis.

01.09.2025 20:06 πŸ‘ 83 πŸ” 23 πŸ’¬ 16 πŸ“Œ 2
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Our lab’s first field harvest at Prosper ND with our amazing folks!

30.08.2025 01:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Zeavolution signup

Starting up our 8th year of the Zeavolution webinar series! Want to hear talks on maize genetics, evolution, phylogeny, genomics, etc? All are welcome! Join our slack with >400 people from across the maize community! DM to join the slack, and check out below for schedule or to sign up for a talk!

27.08.2025 22:31 πŸ‘ 18 πŸ” 7 πŸ’¬ 1 πŸ“Œ 1
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Amazon shipped a box of diaper to my office …

26.08.2025 20:32 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

From my limited interviewing experience, when a reference mentions even a minor concern about a candidate, it’s worth paying attention. What may seem small could point to a larger and major issue, and it’s important to decide whether you’ll be comfortable with that.

21.08.2025 19:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

πŸŽ‰ Congratulations @shanwai1234.bsky.social and team @ndsuofficial.bsky.social!!
Fascinating work, can’t wait to dive in!

28.06.2025 00:01 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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We finally get our brand new LED growth chamber today and have an alternative to waiting in line for the shared equipment!

04.06.2025 16:49 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Shipped out >120 lb packages today

13.05.2025 04:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Our first field season is kicking off!

30.04.2025 16:20 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Yup, we should have two fields this summer

23.04.2025 23:07 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Preparing 50 trays with 4,800 slots for our first large-scale sampling effort

23.04.2025 18:48 πŸ‘ 5 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Proud to see my first PhD student, Ced Fernandez, present his first project on heat stress response at the 2025 Maize Genetics Conference just after he joined our lab for 10 months!

11.03.2025 04:08 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The biggest impact I'll ever have as a professor is the people I help train. Felt wonderful to see so many current trainees and lab alumni together in one place this past weekend at the 2025 Maize Genetics conference.

11.03.2025 00:28 πŸ‘ 10 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Eventually, we have our own lab space today!

11.02.2025 17:52 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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After intense data collection and exploring research goals, we finally held our first lab meeting in a while. Excited to see where this next phase takes us!

24.01.2025 22:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Really fun to reunite with my undergraduate classmates at #PAG32

12.01.2025 21:52 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The first week of 2025: a new student joined, a postdoc’s visa was approved who will come soon, and our very first lab member, who greatly helped with lab setup as a student worker, will become an alumnus by the end of this month, my first experience of joy mixed with sorrow as a faculty.

08.01.2025 01:08 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Growing batches of plants for a new experiment on the Christmas Eve

24.12.2024 19:45 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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When is it subfunctionalization and when is it not? Mutations generate new alleles and gene duplications are required to make new genes. How these two types of events interact can affect evolutionary process

I love when a thought assessment of empirical data shows that a simple concept is really really difficult (shocker).

Jim Birchler on what is and is not subfunctionalization. academic.oup.com/g3journal/ad...

19.12.2024 18:28 πŸ‘ 10 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Thank you @ndsurca.bsky.social for your support and helping us drive innovation!

18.12.2024 03:09 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The genetics of inbreeding depression - Nature Reviews Genetics The genetic basis of inbreeding depression and of the related phenomenon, heterosis, has been a puzzle for many decades. Based on recent studies in many species, the authors argue that both phenomena ...

Just your regular reminder how awesome this review on inbreeding depression is. www.nature.com/articles/nrg...

04.12.2024 21:33 πŸ‘ 59 πŸ” 22 πŸ’¬ 1 πŸ“Œ 1
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Leaves on a wild barley are much glossier than those on barley cultivars

30.11.2024 15:56 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
B1G Impact Research: Corn Genetics
B1G Impact Research: Corn Genetics YouTube video by University of Nebraska–Lincoln

The Big 10 Impact Research clip on our lab's corn science played during the Nebraska/Wisconsin game. Also we beat Wisconsin. Coincidence? ...probably yes... www.youtube.com/watch?v=5nm8...

24.11.2024 00:59 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

A neat bit we found out in revisions (now submitted). Our full data set shows that TF binding site variation explains >50% of Va for 60% of traits. But many of our binding site variants were epigenetic -- methylation changes that impact TF binding.

23.11.2024 22:18 πŸ‘ 68 πŸ” 19 πŸ’¬ 6 πŸ“Œ 2
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Our first emasculation work in spring wheats

23.11.2024 21:16 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0