Congrats Josh and team! May have to present this paper next time it’s my turn for lab meeting….

A neuromodulatory circuit-to-molecular pathway for reformatting aversive memories during recall Tan et al. identify a neuromodulatory circuit-to-molecular pathway in rats that updates aversive memories when they are recalled. Noradrenaline from the locus coeruleus triggers synapse-to-nuclear tra...

Excited to share our new paper:
We uncover a locus coeruleus→amygdala circuit linking β-adrenergic signaling to transcription regulation in defined amygdala cells during memory reconsolidation—+ stress or elevated noradrenergic signaling at recall can strengthen memory.
www.cell.com/neuron/abstr...

UAB is recruiting neuroscience faculty at two different levels - come join our vibrant neuroscience community!

yes, please

Looks like fun never been oystering before

He trained my PhD advisor in grad school

Congrats Kate and team!

Next-generation multicolor indicators for in vivo imaging of norepinephrine - Nature Methods Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...

The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...

New postdoctoral opportunity @lieberinstitute.bsky.social working w/ @tsawada1.bsky.social and our Molecular Neurogenetics team using human induced pluripotent stem cells to investigate molecular, cellular and neuroendocrine mechanisms by which impaired placental function impacts brain development

New Special Issue out in #AddictionNeuroscience edited by @talialerner.bsky.social on dopamine circuitry and heterogeneity in addiction with articles by @daylab.bsky.social, Tom Hnasko, @mtorregrossa1.bsky.social, and Awatramani Rajeshwar check it out! www.sciencedirect.com/special-issu...

Congrats Ben that is a high honor indeed!

A Common Iba1 Antibody Labels Vasopressin Neurons in Mice There are a wide variety of commercially available antibodies for labeling microglial cells based on different protein targets, as well as antibodies for the same protein target made in different spec...

PSA for all #microglia lovers: certain Iba1 antibodies (see our new paper below for details) label not only microglia, but also vasopressin neurons, at least in mice. Brain region and species matter. A friendly reminder to always validate your antibodies! 🔬

www.eneuro.org/content/13/2...

You beat me to it!

Did you skate?

Grateful for all the amazing collaborators too numerous to list (check the author list), but several folks from my group and teams the labs of @mikebeckstead.bsky.social, Srikant Ranguraju, Andrew Varga, and @martinowk.bsky.social contributed.

Hyperphosphorylated tau first appears in the LC in the earliest stages of AD, decades prior to cognitive impairment. Anu expressed P364S tau in the LC. After 3 months, she observed pTau, neuroinflammation, LC hyperactivity, hyperarousal/anxiety, and LC-NE specific transcriptome and proteome changes.

Excited to share newly minted PhD Anu Korukonda's tour de force thesis work describing the impact of pathogenic tau on #locuscoeruleus function in a mouse model of early #Alzheimers. A must for #BlueSpot researchers! www.biorxiv.org/content/10.6...

1/3

🧵Good news out of #NIH today.
(1) NIH is extending #ESI and #K99/R00 eligibility to accommodate researchers whose eligibility would have ended during the previous shutdown. Take a look at NOT-OD-26-020. If your ESI status would have ended in 2025, you get an automatic extension through 2026/03/31.

👇New biosketch requirement update.

“After evaluating the number and types of recent technical inquiries we received to both the SciENcv and eRA Service Desks, we recognize the difficulties these issues have had on the community’s ability to comply with the original timeline of January 25, 2026.”
👇

Adolescent Social Isolation Facilitates Tau Spread in Raphe Nuclei Linking Depression and Hyperalgesia in Alzheimers Disease https://www.biorxiv.org/content/10.64898/2026.01.23.701108v1

So jealous!

Publication of the Year Award - Nomination Thank you for submitting your Nomination!

The Neuromodulatory Subcortical Systems PIA within @istaart.bsky.social is requesting nominations for the best paper of 2025 on neuromodulatory subcortical systems in Alzheimer's disease!! ISTAART members: promote the work of your colleagues (or yourself) here: alz.surveymonkey.com/r/Publicatio...

Summer Internship Summer internship

Applications for our summer internship program are open. This is a paid, 9 week experience designed to provide research experience to undergraduates interested in the neurosciences, especially as related to the molecular and cellular basis of neuropsychiatric disorders

www.libd.org/summer-inter...

Fascinating work congrats!

It took me about an hour but still haven’t been able to download a copy

Love Radiolab!

Congrats to all of the new @acnporg.bsky.social Members!!!
#ACNP2026

Rematch tomorrow!

He’s definitely better than me but hopefully gave him a run for his money

Fun tennis with Mark Thomas at #ACNP2026!