Dr Michael Pitcher

Happy birthday to one of my favourite haters, Charles Darwin

Proud to be part of the bioinformatics team at PharosAI working on this exciting project utilising @10xgenomics.bsky.social Xenium spatial transcriptomics platform to help build a multimodal cancer dataset.

Queen Mary's Barts Cancer Institute co-leads £43.6m initiative to accelerate AI-powered cancer breakthroughs - Barts Cancer Institute - Queen Mary University of London Barts Cancer Institute, Queen Mary University of London will co-lead a ground-breaking collaboration, PharosAI, that aims to harness cutting-edge artificial intelligence (AI) and unlock decades of NHS...

We're excited to co-lead a ground-breaking collaboration, PharosAI, that aims to harness cutting-edge artificial intelligence and unlock decades of NHS cancer data. The UK government has committed £18.9m to the project.

#medsky 🧪 @qmul.ac.uk @qmulfmd.bsky.social www.bci.qmul.ac.uk/general-news...

Excited 😁

Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of esophageal cancer Nature Cancer - Ganguli et al. show that CDKN2A loss in Barrett’s esophagus prevents esophageal adenocarcinoma initiation by counterselecting subsequent TP53 loss and report context-dependent...

Best start of 2025: our study on the dual role of CDKN2A in cancer evolution (rdcu.be/d5pty) is out in @naturecancer.bsky.social! Big thanks to Piyali Ganguli who led it, all coauthors and @cancerresearchuk.org archuk.org @crick.ac.uk @qmbci.bsky.social bci.bsky.social for support! Summary below

Method of the Year 2024: spatial proteomics - Nature Methods Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.

Our lab has done a lot of work with Imaging Mass Cytometry (with more to come soon 👀), so it's great to see Spatial Proteomics announced as Nature Methods' Method of the Year for 2024! Exciting time for the field and lots of advancements to come
www.nature.com/articles/s41...

Method of the Year 2024: spatial proteomics - Nature Methods Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.

I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...

Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network

Below are the links

If you're an immunologist and I have missed you so far, let me know 🧪

go.bsky.app/PY5tCas

go.bsky.app/FmERUoD

go.bsky.app/6aT6qDS

Could I be added please?

Could tolerance to DNA be broken in the gut in systemic lupus erythematosus?

New review from Jo Spencer and Sahil Jain exploring whether tolerance to DNA can be broken when undigested DNA from microbiota in GALT directly encounters B cells unrestricted by T cell dependence

doi.org/10.1016/j.im...