Dafne Campigli Di Giammartino

🚀 My lab 3d-chrom.iit.it is recruiting a PhD student within the INT2ACT Marie Curie Network 🌍🧬
If you want to work with epigenetic/epitranscriptomic tools + 3D chromatin assays to study how ncRNAs shape genome organization and gene expression apply to DC12 by Jan 31st int2act.eu/open-positio...

🧬We’re hiring a Senior Bioinformatician @IIT in Genova 🇮🇹
Join our lab 👉 3d-chrom.iit.it to explore how non-coding RNAs shape 3D genome architecture
⏰ Deadline Nov 16th- only a few days left to apply!
app.ncoreplat.com/jobposition/...

🚨For chromatin, epigenetics and non-coding RNA lovers: only two more weeks left to apply!

Check out our lab page and if interested don't hesitate to apply 3d-chrom.iit.it

Research Technician
app.ncoreplat.com/jobposition/...

Senior Researcher-Technologist
app.ncoreplat.com/jobposition/...

🎯 Our lab at the Italian Institute of Technology 3d-chrom.iit.it has a technician position available

If you are a scientist, interested in chromatin 🧬 epigenetics and non-coding RNAs and you are looking to work in a stimulating environment don’t hesitate to apply
👇
app.ncoreplat.com/jobposition/...

🚨 Last Call for Applications! 🚨
If you're passionate about chromatin 🧬 and non-coding RNAs, you have only a few days left to apply:

Three fully-funded positions in my lab to study the cross-talk between epigenetics and 3D chromatin architecture.

Application links are available in the post below 👇

I am so happy to see this work finally out 🎉 authors.elsevier.com/c/1kqIJ_Oylr...

Thanks to all the authors for the incredible teamwork!!!

To all chromatin and RNA enthusiasts 🧬 🧬 🧬

Our lab 3d-chrom.iit.it has several openings!

Looking for a well-paid position in a stimulating environment?

Apply here 👇

Senior Bioinformatician
iit.taleo.net/careersectio...

Senior Molecular Biology Researcher
iit.taleo.net/careersectio...

Deletion of a single CTCF motif at the boundary of a chromatin domain with three FGF genes disrupts gene expression and embryonic development Chromatin domains delimited by CTCF can restrict the range of enhancer action. However, disruption of some domain boundaries results in mild gene dysr…

Here is the peer-reviewed version of our study showing how some TAD borders are essential for gene regulation and development.

Loss of a single CTCF motif is sufficient to cause embryonic lethality.

www.sciencedirect.com/science/arti...

Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion Prior studies showed that structural loops collapse upon acute cohesin depletion, while regulatory enhancer-promoter (E-P) loops largely persist, consistent with minimal transcriptional changes. Howev...

New preprint from the lab investigating the role of cohesin in the establishment of chromatin loops and transcriptional programs after cell division or during cell fate transitions. Study led by @ukjinlee.bsky.social. Grateful to the whole team and NIH for support!

Enhancer Mechanics and Enhanceropathies Join us for the highly anticipated third EMBO workshop on Enhancer Mechanics and Enhanceropathies! Building on the success of our previous meetings in Santander (2021) and Marseilles (2023), this eve…

Together with @smandrup.bsky.social and Minna Kaikkonen we are happy to announce the 3rd Edition of the EMBO Workshop on #Enhancers and #Enhanceropathies. This time we will meet during the beautiful Danish summer (June 16-21).

Book the dates and register soon!!!

meetings.embo.org/event/25-enh...

Very cool collaboration with @andersshansen.bsky.social's lab on how to calibrate Micro-C using our labs' previous live-cell estimates of looping probability!

Enhancer scrambling strategy

We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵
www.biorxiv.org/content/10.1...