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Paul Brennan

@paulnbrennan

Academic Hepatologist, MASLD, epidemiology and public health and policy Rugby enthusiast ๐Ÿ‰ and odd heavy guitar ๐ŸŽธ riff Irishโ˜˜๏ธ ๐Ÿ‡ฎ๐Ÿ‡ช in exile in Scotland ๐Ÿด๓ ง๓ ข๓ ณ๓ ฃ๓ ด๓ ฟ

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18.11.2024
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Latest posts by Paul Brennan @paulnbrennan

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The People-First Liver Charter - Nature Medicine Reducing the stigma and discrimination that people living with liver conditions experience requires rethinking how diagnoses, diseases, etiologies and circumstances are perceived โ€” a shift that begins...

At the Global Think-tank on Steatotic Liver Disease, we launched the People-First Liver Charter
www.nature.com/articles/s41...

+ A call for doubling the diagnostic rate of at-risk MASH
www.thelancet.com/journals/lan...
#SLDthinktank #InMotionTogether #LiverSky

08.06.2025 13:27 ๐Ÿ‘ 6 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The People-First Liver Charter - Nature Medicine Reducing the stigma and discrimination that people living with liver conditions experience requires rethinking how diagnoses, diseases, etiologies and circumstances are perceived โ€” a shift that begins...

Happy to support and endorse the People First Liver Charter in
โ€ชโ€ช@natmed.nature.comโ€ฌโ€ฌ www.nature.com/articles/s41...

We've always taken a sensitive approach to the language used in our journal, and will continue to do so. See this Editorial www.nature.com/articles/s41...

09.06.2025 12:31 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Role of anti-diabetic medications in the management of MASLD | FG Podcast The use of anti-diabetic medications such as pioglitazone or GLP-1 receptor agonists in the management of metabolic dysfunction-associated steatotic liver disease (MASLD) is discussed in this podcast....

It was a real pleasure to interview Scott Isaacs and @paulnbrennan.bsky.social regarding their recent paper on 'Anti-diabetic medications in MASLD' in Frontline Gastroenterology - listen below

fgbmj.podbean.com/e/role-of-anti-diabetic-medications-in-the-management-of-masld/

28.05.2025 08:32 ๐Ÿ‘ 6 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Role of anti-diabetic medications in the management of MASLD Metabolic dysfunction-associated steatotic liver disease (MASLD) poses a significant global health challenge due to its rising prevalence and strong association with metabolic syndrome and type 2 diab...

New review in #FG from @paulnbrennan.bsky.social and #scottisaacs - a great summary of the role of antidiabetic medications in MASLD #liversky

fg.bmj.com/content/earl...

21.02.2025 15:34 ๐Ÿ‘ 2 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The ๐ŸŒŽ burden of #MASH is staggering: 5.3% of adults face higher risks of cirrhosis, liver cancer & other complications as fibrosis progresses.
our latest study on MAESTRO-NASH resmetirom data & its real-world implications post-FDA approval www.nature.com/articles/s44... #SLDsummit

23.01.2025 11:14 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Thanks for highlighting our paper @dufourjf.bsky.social! Challenging to undertake these trials in ACLD but hopefully offers some potential utility, more from this cohort to come in our long term follow up analysis this summer ๐Ÿคž

13.01.2025 21:02 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Autologous macrophage therapy for cirrhosis: phase 2 open-label randomized controlled trial: During 360-d follow-up, control group developed 4 liver related events, and 3 deaths (2 liver related), whereas no liver-related severe adverse events or deaths occurred in the treatment group.

11.01.2025 09:45 ๐Ÿ‘ 6 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

My take away is that immediately pre- surgery the Post-TIPSS group had worse MELD composites, whilst they had good PSM controlling at time point 6 months before, they were clearly less robust at time of intervention. What about matching with similar non-TIPSS MELD controls at time of op?

06.01.2025 22:59 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The Jan 2025 issue of The Lancet Gastroenterology & Hepatology is out today at www.thelancet.com/gastrohep!

Content includes UPFs, Crohnโ€™s disease, rectal cancer, coeliac disease, MASLD + heart disease, gastroparesis + moreโ€ฆ

#GastroSky #LiverSky #MedSky

12.12.2024 06:14 ๐Ÿ‘ 22 ๐Ÿ” 5 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0