Cryo-EM reveals how a bat coronavirus related to MERS may jump to mink — and potentially humans. Researchers from Yale and NIH used Apollo to solve the HKU5 spike–ACE2 structure, uncovering a unique binding strategy and host range. Read the study: https://doi.org/10.1038/s41467-025-61583-7
ICYMI: HyperSpy wins the People’s Choice Award! The open-source Python library for interactive analysis of complex materials data—co-developed with major contributions from Direct Electron scientist Carter Francis—was honored at France’s 2025 Open Science Awards.
https://ow.ly/fmvu50Yomlr
We’ve added our latest webinar to the product demos and technical presentations on our Videos page. Explore recordings covering our cameras, workflows, and real-world research applications.
Visit: https://directelectron.com/videos/
Missed our recent webinar on the DE API for Direct Electron cameras and scan controllers? The recording is now on YouTube! Explore integration strategies and advanced workflow control with R&D Scientist Dr. Carter Francis. View the full recording: https://youtu.be/kJi1kLvHcGo
Our Applications Scientist Dr. Barnaby Levin will be will be talking about MAPS Detectors for TEM at the Transmission Electron Microscopy for Materials Research Gordon Research Conference, February 15–20. Don't miss him if you're there & follow us for updates.
Learn more: https://ow.ly/yrRM50YfrVF
First-ever EBSD orientation maps of hafnia & hafnon: using SEMCam + dictionary indexing, researchers overcame beam sensitivity & low symmetry challenges in ceramics. A new path for difficult materials. Read more: https://ow.ly/7Mn850YeA3K
API WEBINAR - WEDNESDAY, FEB 11!
Join R&D Scientist Carter Francis for a practical demo, learn to use Python to control and automate DE cameras for live data visualization, experiment automation, Jupyter workflows, and other new features.
Sign up here: https://ow.ly/hAOz50Y5Jrz
Tired of manual bottlenecks slowing your research? Join our free webinar with R&D Scientist Carter Francis to learn how Python-based camera control enables experiment automation, live data visualization & reproducible workflows. Feb 11, 9am PST. Register here: https://ow.ly/FABK50Yas1r
API WEBINAR - ONE WEEK, FEB 11!
Join R&D Scientist Carter Francis for a practical demo, learn to use Python to control and automate DE cameras for live data visualization, experiment automation, Jupyter workflows, and other new features.
Sign up here: https://ow.ly/hAOz50Y5Jrz
API WEBINAR - FEBRUARY 11th!
Learn how to use Python to control and automate Direct Electron cameras. Join R&D Scientist Carter Francis for a practical webinar covering live data visualization, experiment automation, Jupyter workflows, and new features.
Sign up here: https://ow.ly/cioN50Y5Jrl
Our Applications Scientist Dr. Barnaby Levin is attending the Liquid Phase Electron Microscopy Gordon Conference this week, where he’s presenting a poster on in situ TEM and in situ 4D STEM with fast direct detectors. If you’re at the meeting, don’t miss it!
https://ow.ly/O0Zv50Y5Cbj
Researchers at UCLA show you don’t need a dedicated cryo-EM to get world-class results. Using an adapted entry-level TEM, they achieved 1.95 Å apoferritin—comparable to top-tier systems—pointing to a more accessible future for cryo-EM.
Read more: https://doi.org/10.1093/mam/ozae044.364
What makes our direct detectors so special? Let our customers tell you!
Learn all about DE-64 & Direct Electron's other ultra-fast cameras for Electron Microscopy & CryoEM at https://directelectron.com/products/
Unlocking atomic detail in seconds: Apollo enables high-speed, low-dose MicroED for microscale and nanoscale crystals—accurate structure solutions in less than a minute of data collection.
Learn more about these groundbreaking results: https://ow.ly/SB8k50Y0ocO
Want to know what sets Direct Electron apart? Let our satisfied customers tell you!
To learn more about Apollo & our other ultra-fast cameras for Electron Microscopy & CryoEM, visit https://directelectron.com/products/
We’re excited to share a new Journal of Virology study where researchers used our Apollo camera to map VEEV at high resolution and identify a cross-neutralizing antibody that could support development of a pan-alphavirus therapeutic.
Read the paper: https://ow.ly/7Z3850XTLIU
Proud to see the Apollo camera supporting new H5Nx bird flu research in Nature Microbiology. NIH scientists imaged 500 antibodies from an H5N1-vaccinated patient and identified 5 that cross-neutralize multiple strains—key for future vaccine design.
https://www.nature.com/articles/s41564-025-02137-x
Wishing you a Happy New Year filled with research breakthroughs, innovative discoveries, and scientific milestones made possible by the Most Advanced Direct Detection Cameras for High-Speed Electron Microscopy!
New paper from the Gianola group (UC Santa Barbara)! The first-ever EBSD patterns sliced by electron energy, enabled by direct detection with the DE-SEMCam. Results vs EMSoft simulations show how energy filtering sharpens HR-EBSD versus EBSD patterns.
Read it here: https://ow.ly/zeaW50XMLOX
HyperSpy wins the People’s Choice Award! The open-source Python library for interactive analysis of complex materials data—co-developed with major contributions from Direct Electron scientist Carter Francis—was honored at France’s 2025 Open Science Awards.
https://ow.ly/5ZJu50XL9zo
Learn HyperSpy from one of its pioneers. DE's Dr. Carter Francis (HyperSpy steering council, lead developer of pyxem) kicks off the GLMS HyperSpy webinar series with an intro for TEM users.
Sign up here: https://umich.zoom.us/webinar/register/WN_NcKlNfTSQW-ppeq4tLivuQ#/registration
Where in the world is Direct Electron? Applications Scientist Dr. Barnaby Levin was just at the 2025 MRS Fall meeting, so if you guessed Boston, you got it right! Now for the real challenge—can you name the building?
Dr. Barnaby Levin says "it was great to be at MRS and hear about new & exciting science!”
Direct Electron is on the move again—stay tuned for more stops around the globe.
In a direct comparison on the same sample, Apollo outperformed both K3 and DE-64—achieving 2.24 Å resolution vs ~2.9 Å for K3. Higher detail per particle and better DQE make Apollo the clear leader in cryo-EM detector performance.
Read more: https://ow.ly/aF7950XgCWZ
Don't miss Dr. Barnaby Levin tomorrow, 2:45 PM at the Fall MRS Meeting presenting:
“Advances in Event-Based Direct Detectors for In Situ TEM.”
Hear how next-gen detectors + cutting-edge software are unlocking ultrafast, high-res imaging of dynamic processes.
Learn more: https://ow.ly/g6vG50XAizy
🍁 We’re grateful for innovation, collaboration, and all the brilliant minds driving scientific progress. Wishing you and yours a day of gratitude, connection, and lots of tasty food! 🦃
Thanks to all who played along with "Where in the World is Direct Electron?" this week! Here’s another shot from Kalani’s latest stop in Europe.
This time the landmark is a giveaway — so, if you guessed Strasbourg, France, you nailed it!
Where in the World is Direct Electron? Senior Applications Scientist Michael Spilman (right) stopped by Aalto University in Finland to visit OtaNano Senior Scientist Jani Seitsonen & their JEOL 3200FSC, now running a brand-new Apollo (right next to their trusty DE-16).
Where in the world is DE Director of R&D Dr. Benjamin Bammes This week, it's the Rice University Center for Nanoscale Imaging Sciences Conference, attending Prof. Steve Ludtke’s talk on how continuous-rotation tomography + the DE Apollo improves contrast & reduces 3D artifacts.
Our R&D Scientist Kalani Moore is out in the field supporting our customers — but Where in the World is he?
Recognize the beautiful building behind him? Give us your best guess!
