Florey Lab

I am looking for a post/doc! Are you motivated to study the fundamental questions in autophagy? Have a look!

We are pleased to welcome Prof Sir Jim Smith as the Institute's Interim Director.

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Don't miss out on attending the Mar 15-20th 2026 GRC on #Autophagy in Ventura, California! All the latest findings from the field - check out the program and come tell us about your amazing science.
www.grc.org/autophagy-in...

Don't miss out on hearing all the latest #autophagy discoveries at the 2026 GRC meeting in Ventura, US. We and the amazing line up of speakers look forward to meeting YOU 🫵. Follow link to register!!!
www.grc.org/autophagy-in...

Check out the line up of amazing speakers at the 2026 GRC Autophagy meeting in Ventura, California, 15-20 March. Register now and share your latest findings.
www.grc.org/autophagy-in...

a man in a tuxedo and suspenders is holding a baton and says science ALT: a man in a tuxedo and suspenders is holding a baton and says science

Want to hear about the latest #autophagy discoveries? Join us in Ventura California for the 2026 GRC Autophagy meeting 15-20 March. Keynote speakers Sharon Tooze, Eileen White and Ivan Dikic.
Registration open now⬇️ Bring your science!
www.grc.org/autophagy-in...

Join us in sunny California for the 2026 GRC Autophagy meeting! Excited to co-chair with Oliver Florey and vice chairs Helene Knaevelsrud and @robzonculab.bsky.social
Keynote speakers incl. Eileen White, @idikic.bsky.social and Sharon Tooze- Registration is open: link⬇️ www.grc.org/autophagy-in...

Last day in the lab for student Jake @jakecross96.bsky.social. So we had a naming ceremony for a freezer in his honor. Good luck at the @cellbiol-mrclmb.bsky.social

Restriction on Entry of Certain Nonimmigrant Workers BY THE PRESIDENT OF THE UNITED STATES OF AMERICA A PROCLAMATION The H-1B nonimmigrant visa program was created to bring temporary workers into the United

This will end up being another attack on research institutions in the US. I worked in New York on an H1 visa for many years. It benefited me and the lab I was in. Would it have happened if I cost an additional $100,000 per year?
www.whitehouse.gov/presidential...

a man in a suit and tie is saying `` i have no words '' . ALT: a man in a suit and tie is saying `` i have no words '' .

So, Farage wants to kick out my mum, a French citizen who has lived, worked, paid taxes and raised 2 kids in the UK for over 50 years. I'll make sure to yell at her to "go back to where you came from".

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Don't know about him joining ICE.....

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It is disappointing. Some real results are sunk by lazy and deceitful decisions on others. How many research hours/$$££ are wasted following some of those observations?

Another excellent study showing #CASM at play in plant stress responses!

My guess... the LC3B structures are not all autophagosomes #CASM

Neighbors may not like our overgrown lawn. But if it lets wild flowers like this grow, who cares! Bee Orchid #biodiversity

Thanks, and the same to you too.

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7 months later....BBSRC grant scored 6,6,5,4 (out of 6) - rated excellent. Committee D: Not funded.

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How I arrived on Bluesky

Say Hi to Mike Overholtzer if you see him!

Sometimes science can wait

Unbelievable. Richard Youle, winner of the Breakthrough Prize for Life Sciences, just got fired from the NIH. If you want to know what madness looks like, here it is, my friend.

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It was wonderful to be part of this story. Well done everyone. We enjoyed hosting you and look forward to your return this summer!!

🚀Our latest work reveals how RAB5c orchestrates LC3-associated phagocytosis (LAP) to boost macrophage defense against A. fumigatus! 🦠🔬
🧵 Dive into the mechanisms linking endosomal traffic to innate immunity!
#Immunology #Autophagy #Phagocytosis #Macrophage #Preprint
doi.org/10.1101/2025...

Congrats to Ian Ganley of Dundee University on winning the #BSCB Hooke Medal 🥇for his outstanding work on mitophagy 🎉🎉🌟

Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages Ca2+ leakage triggers LC3 lipidation on multimembrane as Mtb phagosome damage response, independent of autophagy.

Happy to share the latest work from the lab @crick.ac.uk. Outstanding work from Di Chen and Tony Fearns showing the link between Mtb membrane damage, calcium leakage and ATG8/LC3 lipidation in macrophages. Congratulations Di and Tony!
www.science.org/doi/10.1126/...

Really cool story. Congrats all ! (although, I would still call this process CASM 😉, multimembrane compartment probably started out as a single membrane one)

Uhh yeah. What is it good for? Absolutely nothing

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Twitter suffered an outage….. and I didn’t even notice.

Spontaneous transformation/emt? Can happen in mcf10a cells if a bit old and left too confluent.

VitA and nutrition for measles, are the thoughts and prayers for mass shootings