Great study and a nicely succinct explanation below!
Great study and a nicely succinct explanation below!
Gltp ko in mouse is also lethal
We are looking for a postdoc to study biomolecular condensates and/or mechanosensitive membrane proteins. Please help spread the news π
sites.rutgers.edu/shi-lab/look...
Groundbreaking study in Cell from @leventallab.bsky.social: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes β major implications for how this membrane works. A #lipidtime must-read! www.cell.com/cell/abstrac...
If youβre in San Diego for #ACSSpring2025, donβt miss our @acsbiol.bsky.social symposium featuring @chembiobryan.bsky.social, Jenn Prescher, & Carsten Schultz on Wed 3/26 from 2-5 pm in Room 31A to hear about awesome #lipidtime #bioorthogonal #chembio #synbio! acs.digitellinc.com/live/34/sess... 2/2
Congratulations!! π
Itβs my honor you like the work. Too bad there arenβt any galactose analogs I can use π₯Ή
However, myelin growth occurs at the innermost layer of myelin wrap-far from and difficult to access from the cell body. This led us to hypothesize that oligodendroglial ER extends into the myelin, allowing lipids to be synthesized locally and delivered directly to myelin (3/n)
As an enthusiast of ER and membrane biology, I find oligodendrocytes fascinating because they are among the human bodyβs most powerful lipid producers. To generate myelin, each cell must expand its plasma membrane thousands of times. (2/n)
My first-author #lipidtime paper is out
@NatureComms
! We studied how oligodendrocytes produce myelin. Using volume EM, we characterized oligodendroglial ER (magenta) in mouse developing myelin and explored nonvesicular lipid transport involved doi.org/10.1038/s414... (1/n)