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John Dennehy

@drjdennehy

We are the resistance, not because we chose to be, but because we have no other choice.

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07.08.2023
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Latest posts by John Dennehy @drjdennehy

If you block junior scientists from ensuring that they can afford to live (or start families!) in the exorbitantly expensive areas around their workplaces, only family-subsidized solitary rich kids will be able to pursue careers in research - amidst exponential inflation, increasingly few people.

06.03.2026 17:21 πŸ‘ 97 πŸ” 27 πŸ’¬ 0 πŸ“Œ 4

Current NIH leadership want you to think they are using rigorous, consistent & scientific processes to screen studies to align them with agency priorities.

But the process that they have put down on paper is a sham.

It’s important to know NIH is not following its own guidance. Here’s why:

🧡1/

06.03.2026 14:35 πŸ‘ 194 πŸ” 122 πŸ’¬ 4 πŸ“Œ 10
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Stand Up for Science
New York City National Day of Action Rally!
Saturday, March 7, 12pm - 2pm
City Hall Park

Rally to defend scientific integrity, protect public health, and protest political interference in the scientific enterprise.

Meet PSC members at the Broadway and Park Place entrance.

06.03.2026 01:12 πŸ‘ 11 πŸ” 7 πŸ’¬ 0 πŸ“Œ 1
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Hoping for a big turnout tomorrow!

06.03.2026 13:14 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Sabotaging the NSF fellowship is a blunder Over the last year, the Trump administration has sent one discouraging message after another to young people aspiring to a scientific career in the United States. The corrosive rhetoric that mocks sci...

Sabotaging the NSF fellowship is a blunder

"After making a massive mistake of curtailing the entry of excellent foreign-born scientists, the administration is compounding the error by further restricting the development and availability of domestic scientists."

www.science.org/doi/10.1126/...

05.03.2026 20:25 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thank you for your service @nmrkaygee.bsky.social !

05.03.2026 19:41 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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New paper showing that bacteria with more genes for cooperation can live in a broader range of habitats and that genes for cooperation are more more likely to be in the accessory genome www.pnas.org/doi/10.1073/... @lauriebelch.bsky.social

04.03.2026 10:23 πŸ‘ 54 πŸ” 24 πŸ’¬ 2 πŸ“Œ 0

In our latest work, we characterise the Tmn defence system. We reveal plasmolysis as a new way to block phage infection, dramatically reducing secondary infections.

03.03.2026 19:55 πŸ‘ 27 πŸ” 19 πŸ’¬ 1 πŸ“Œ 1
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Profile: Dr. Caroline M. Solomon - The Mind Hears I tell my students that learning isn’t a one-size-fits-all experience. I would tell younger Carrie to try new things and find new ways of experiencing life.

Great profile of @ntidpres.bsky.social in the @themindhears.bsky.social

themindhears.org/2026/02/25/p...

03.03.2026 20:50 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Epistasis and co-adaptation in bacterial genome evolution Nature Reviews Genetics - Bacterial genome evolution is shaped by epistasis, which can constrain or promote specific evolutionary paths. The authors review how integrating the effects of epistatic...

I’ve spent a lot of time over the past two years thinking about genome evolution and how recent research revealing complex gene-gene interactions has complicated traditional β€˜gene-centric’ genomic approaches to evolution. So here is a review that consolidates these thoughts!

rdcu.be/e6pHY

02.03.2026 15:48 πŸ‘ 85 πŸ” 39 πŸ’¬ 4 πŸ“Œ 1
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With Eugene Koonin, we propose a concept of β€œthe selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268

03.03.2026 08:58 πŸ‘ 222 πŸ” 95 πŸ’¬ 5 πŸ“Œ 13

The number of researchers who*don't even respond* to review requests is appalling. If you can't or don't want to review, fine. But don't waste everyone's time by ignoring three or four emails that can be dealt with one click.

03.03.2026 13:34 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Claire Shipman is a former television journalist, and it shows.

Going live to tape and telling the world how your university was invaded and your student abducted on the same day is exactly how you fight authoritarianism.

27.02.2026 15:05 πŸ‘ 73 πŸ” 25 πŸ’¬ 1 πŸ“Œ 2
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Cover of The Lancet:

@thelancet.com
www.thelancet.com/journals/lan...

27.02.2026 11:15 πŸ‘ 8162 πŸ” 3445 πŸ’¬ 158 πŸ“Œ 221

I'll translate it for you Dave. There's going to be a small club getting funded and you're not in it.

Grantmaking will become industrial policy executed through academia.

27.02.2026 13:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I've been using Google Notebook where you can upload a paper collection and ask questions about it. I find it really helpful in writing where I can ask it to find information in the collection quickly e.g. "which paper experimentally manipulated X to test Y?" Beats manually scanning a bunch of PDFs.

26.02.2026 17:41 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Federal funding for US biomedical research is moribund.

Since October 1 2025, NIH is -80% in new grants and -70% in values (total dollars).

Labs are closing down and researchers are leaving science.

To what end?

26.02.2026 15:48 πŸ‘ 71 πŸ” 57 πŸ’¬ 5 πŸ“Œ 12

"Stunning bat cave footage captures disease spread risk for first time". Amazing footage of wildlife interacting with bats at the "Python Cave" in Uganda.

26.02.2026 15:50 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

What’s holding back clinical use of phage therapy in the UK?

Our workshop last year brought together international experts, biotech and regulators to find out

Meeting Report out now in Nature Microbiology with our take on the challenges and opportunities facing the UK phage therapy sector

14.02.2026 17:54 πŸ‘ 46 πŸ” 21 πŸ’¬ 1 πŸ“Œ 0

Only have about a week left to comment on this--DoE trying to remove many areas from being classified as a "professional" degree, including nursing and public health. This will limit access to student loans and ultimately drive students from the fields.

24.02.2026 14:04 πŸ‘ 73 πŸ” 70 πŸ’¬ 5 πŸ“Œ 1
the evolutionary and ecological consequences of cooperation

the evolutionary and ecological consequences of cooperation

the evolutionary and ecological consequences of cooperation

the evolutionary and ecological consequences of cooperation

Huge thanks to @asn-amnat.bsky.social for inviting our review on the evolutionary and ecological consequences of cooperation. @annadewar.bsky.social @asgriffin.bsky.social @lauriebelch.bsky.social www.journals.uchicago.edu/doi/10.1086/...

12.02.2026 20:18 πŸ‘ 35 πŸ” 13 πŸ’¬ 1 πŸ“Œ 3

New round of NSF GRFP declines without review. If you were affected:
1) Write NSF
2) Write your Congressperson
3) CC us at grfp@grant-witness.us so we can compile + follow up

Details and template at grant-witness.us/grfp-letter

This is the link to the post: bsky.app/profile/noam...

05.02.2026 15:27 πŸ‘ 33 πŸ” 35 πŸ’¬ 0 πŸ“Œ 3
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Spatial structure: shaping the ecology and evolution of microbial communities Spatial structure naturally emerges in microbial communities, shaping growth, interactions, and evolution, and revealing how microscale processes scale up

Most microbes don't live in shaking flasks; spatial structure shapes how microbes interact and evolve at every scale, as we discuss in our recent review @jeroenmeijer.bsky.social @simonvanvliet.bsky.social @bedutilh.bsky.social @bramvandijk.bsky.social and others
academic.oup.com/femsre/artic... πŸ§΅πŸ‘‡

12.02.2026 15:46 πŸ‘ 49 πŸ” 28 πŸ’¬ 2 πŸ“Œ 3

It's most likely true. If they had actually read our grant, they would have realized there was nothing DEI related in it. But it was terminated anyway.

19.02.2026 18:49 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
NATIONAL DAY of ACTION
Take back our science, health, and democracy!

Join us
MARCH 7TH, 2026
NEW YORK CITY, NY
and nationwide!

Register, volunteer, and donate!

standupforscience.net/march7

NATIONAL DAY of ACTION Take back our science, health, and democracy! Join us MARCH 7TH, 2026 NEW YORK CITY, NY and nationwide! Register, volunteer, and donate! standupforscience.net/march7

NEW YORK CITY! Join your local March 7th rally to take back our science! Learn more at standupforscience.net/march7

#rally
#March7
#ImpeachRFKJr
#science
#standupforscience

17.02.2026 21:08 πŸ‘ 71 πŸ” 34 πŸ’¬ 2 πŸ“Œ 1
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mGem: Immune recognition and clearance of bacteriophagesβ€”implications for phage therapy | mBio Bacteriophages (phages) are viruses that exclusively infect bacteria and cannot replicate within eukaryotic cells in the absence of their bacterial host. Discovered in 1915 (1, 2), more than 10 years ...

How to make phages work for you! A big hurdle is you. πŸ§ͺ 🦠 mGem: Immune recognition and clearance of bacteriophagesβ€”implications for phage therapy | mBio journals.asm.org/doi/10.1128/...

05.01.2026 12:59 πŸ‘ 10 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
Post-Doctoral Associate Job Description Summary Organization's Summary Statement: The Department of Biology at the University of Maryland, College Park seeks applications for three quantitative biology postdoctoral fellow po...

Three postdoctoral fellowships in quantitative biology are available as part of a new Quantitative Biology Initiative in the Department of Biology at the University of Maryland.

Best consideration date: 3/14

Job Ad:
umd.wd1.myworkdayjobs.com/en-US/UMCP/j...

Department:
biology.umd.edu/people

19.02.2026 02:49 πŸ‘ 26 πŸ” 36 πŸ’¬ 1 πŸ“Œ 1

ASV members at your service -- check out your ballot!

@szparalab.bsky.social
@drjdennehy.bsky.social
@salehlabparis.bsky.social
@skytree42.bsky.social
@paulturnerlab.bsky.social

Also but not online: Louis Mansky, Liang Deng, Kai Wu, Shou-Wei Ding, Cristina Rosa, David Buchholz & Patrick Creisher

18.02.2026 22:14 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Happy 134th birthday to humans knowing that viruses exist! OTD in 1892 Dmitri Ivanovsky presented his evidence of a tobacco mosaic disease caused by filterable agents (not bacteria!). Martinus Beijerinck confirmed this independently in 1898. And voila, virology is born!

12.02.2026 22:20 πŸ‘ 30 πŸ” 15 πŸ’¬ 1 πŸ“Œ 0
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FDA’s rejection of Moderna threatens to stifle broader vaccine industry Experts say the FDA "moved the goalposts" on Moderna, creating "a destructive precedent that will undermine the future of vaccine development" in the U.S.

FDA's decision not to accept Moderna's flu vaccine filing has sent shock waves through pharma. "When there’s uncertainty about the path to approval & the reliability of the process, that really has pretty serious consequences,” one player told @jasonmast.bsky.social. www.statnews.com/2026/02/12/f...

12.02.2026 21:04 πŸ‘ 465 πŸ” 194 πŸ’¬ 4 πŸ“Œ 37