Patricia Bruijning-Verhagen

Happy to share our recently published paper. Spoiler; overall little protection from pre-exsisting seasonal coronavirus antibodies.
#IDSky #EpiSky

Hear hear!

The entire archive of CDC datasets can be found here.

HUGE shoutout to data archivists- this work is important 👏🙌🏻

archive.org/details/2025...

As academic Bluesky grows, researchers find strengths—and shortcomings Platform fosters collegial interactions among scientists, but potentially limits interactions beyond the academic community

Nice piece on the massive shift of academics from X to Bluesky; www.science.org/content/arti...
#Science #community

Need some good news at the end of 2024? Dr. Katelyn Jetelina @kkjetelina.bsky.social has a good post about some big public health accomplishments from this year. 🧪 yourlocalepidemiologist.substack.com/p/22-public-...

Update: Wastewater poliovirus detections in the EU: a call for continued surveillance and maintaining high vaccination coverage rates On 9 December 2024, Finnish public health authorities reported the presence of poliovirus in wastewater samples in the country. This adds to the recent positive detection of poliovirus in wastewater s...

Vaccine derived poliovirus 2 detected in wastewater in 5 European countries. Genetic studies ongoing. Important reminder that the polio endgame is far from over. Timely vaccination of children remains essential.
#IDSky #MedSky
www.ecdc.europa.eu/en/news-even...

‘Safety signal’ in Moderna’s RSV vaccine studies halts trials of other vaccines for childhood killer Company found signs its shots made some infected kids sicker than expected, casting a new shadow over the previously troubled RSV vaccine field

Major set-back for pediatric RSV vaccine development; mRNA vaccine trials on hold due to safety signals.
#PedIDsky #IDsky
www.science.org/content/arti...

First H5N1 Bird Flu Infections in Pigs Raises Concerns The US Department of Agriculture (USDA) recently identified the nation’s first cases of avian influenza A(H5N1) virus, or H5N1 bird flu, in swine. The infected pigs were 2 of 5 on a noncommercial farm...

This is concerning, pigs can be infected with other flu A subtypes, creating more opportunities for reassortment. Remember the previous flu pandemic started in pigs 😳.

jamanetwork.com/journals/jam...

The consistency of the findings across many different subgroups, ages and vaccine doses further reduces uncertainty on the safety of COVID-19 vaccines with respect to mortality risk.

Dutch study: COVID-19 vaccinations do not explain excess mortality during the pandemic - Research at UMC Utrecht COVID-19 vaccinations do not explain the excess mortality observed during the corona pandemic, according to a study by University Medical Center Utrecht. The results show that, on average, someone who...

#IDsky #Medsky
Happy to share our preprint on COVID-19 vaccination and excess mortality. We add another peace of evidence that vaccines cannot explain the -still partially unexplained- excess mortality during the pandemic. research.umcutrecht.nl/news/dutch-s...

#IDSky #MedSky #publichealth #COVID

Rule of three (statistics) - Wikipedia

Looks fun here. Okay my fav thing in stats. How do you get an upper bound for a confidence interval when you have no events? 3/n

The rule of three. en.m.wikipedia.org/wiki/Rule_of...

This is particularly relevant for LMIC where the costs of PCV vaccines is a major hurdle. But it also reopens the discussion on whether reduced schedules of 1+1 can be considered for infant schedules in the higher valent pneumococcal vaccines now used in many HICs

Effect of a Reduced PCV10 Dose Schedule on Pneumococcal Carriage in Vietnam | NEJM After pneumococcal disease and colonization have been controlled through vaccination campaigns, a reduced pneumococcal conjugate vaccine (PCV) schedule may be sufficient to sustain that control at ...

Important research that supports reduced dosing of PCV10 in infants in settings with sustained herd-immunity. www.nejm.org/doi/full/10....
@pedsid.bsky.social
@idsky.bsky.social
#vaccination

Contact your GP or local health authority for this. Unfortunately the costs of vaccination (around 200 Eur) are not covered by the health insurance.

Pregnant women who wish to protect their newborn for this coming season can consider the maternal vaccine Abrysvo if their due date is before March 2025 (typically the end or RS season). www.rivm.nl/rs-virus/rsv...

Several European countries now offer infant protection against RS illness through maternal vaccination or monoclonal antibodies for newborns. Netherlands will implement as of season 2025/26.

RS season officially started in the Netherlands with GP visits for acute respiratory illness in children 0-4 yo on the rise. (Data from NIVEL: www.nivel.nl/sites/defaul...)