@al-sadylab
Associate Professor | Dad, Husband |Studying the dynamic epigenome with Chromatin Biochemistry, Biophysics, and Single Cell Biology | fission yeast and murine cells | UCSF Microbiology & Immunology | Parnassus
Bay Area Chromatin Club today at UCSF Mission Bay. Great mechanistic talks from UCSF, Berkeley, Stanford, UCSC, and Genentech. High attendance, awesome posters, many great questions and interactions. (Photo credit to Active Motif, who generously support this awesome series). See you at the next one!
Cara will continue her work on coevolution between DNA satellites and essential host proteins in her new lab in the Dept of Genetics at Rutgers! See: genetics.rutgers.edu/people/facul...
Our full BACC lineup of speakers is up! Looks to be a fun program with talks from UCSC, Berkeley, Stanford, UCSF, and Genentech. Take a peek- still slots available to register and present a poster. March 5, 1-5pm
www.eventbrite.com/e/bay-area-c...
Fun as ever at amazing w-qBIO! This year the kids that grew up in this meeting kicked it off and introduced some plenary speakers. A wonderful tradition and great science. Here organizers that got us going- @hanascientist.bsky.social and Wendell Lim. The work I presented was Entirely qBIO inspired.
Please Rt
Register for the Bay Area Chromatin Club in 2026! It’s free. March 5, 1-5pm Genentech Hall. We have speakers from UCSF, Stanford, Cal, and more ! It’s a great event for trainees to discuss their work and get feedback- bring a poster ! Hang with old and new friends.
urldefense.com/v3/__https:/...
What was eye opening - this is a now critical aspect of education. How do you sort through so much information and prioritize what’s important? How do you communicate that effectively? I gave my first talk at age 26 at the Arabidopsis meeting, totally terrified (it flopped). Gotta start early.
Happy Valentine’s Day! My 12 yr old son got this rose on Jan 22nd for doing a talk in his schools TedX youth event. The rose is still alive after! He says as long as it’s alive he’ll remember his talk. It was really a fun experience, starting August with research, Oct-Dec writing, and talk prep. 1/2
Interested in transcriptional regulation, enhancers and 3D genome folding?
In this new study we wondered about the role of cohesin loading at enhancers for long-range transcriptional control
www.biorxiv.org/content/10.6...
detailed 🧵👇
Maybe it’s my German roots but I generally cannot abide by American Football. But that Half Time show was divine. Bad Bunny, genius.
We are starting Bay Area Chromatin Club up again in 2026! Fist event March 5th at UCSF Mission Bay! Details and registration HERE: If you like to nominate a person for a talk- DM me. It's been a great experience in the past.
urldefense.com/v3/__https:/...
Blissfully ignoring a national celebration of CTE
So so awesome !!
We will miss you @agnisrota.bsky.social !!! The whole
lab wishes you well in your exciting transition.
Same. Stayed on the floor of current student at Cal. Was great.
H3K9 methylation, orange; HP1/Swi6 phosphorylation, purple, illustrating H3K9me3 deposition by Clr4 and its recognition by phosphorylated HP1/Swi6. This design reflects how post-translational modifications enable productive epigenetic reader—writer feedback.
Kudos to Dana Kennedy, for making this lovely, pressed flower cover image for her paper. "Pressed-flower art representing heterochromatin gene silencing in Schizosaccharomyces pombe. Each distinct flower symbolizes HP1/Swi6, Clr4, nucleosomes, and post-translational modifications (cont)
Whimsical addition seen tonight outside a Café trottoir
Introduce yourself with what almost killed you.
Glucose 6 phosphate dehydrogenase deficiency
After much illness finished out at THE French Brasserie- Bofinger just down the street from were we stayed. much history - great meal. First place to serve draft beer in Paris in 1864.
Of two unplanned things on this trip one I didn’t expect: that everyone got sick in Paris in December - ok not surprised. That we had a full blown snow ball fight- wasn’t on my bingo card
Paris in a new light
NYE stroll in Paris with family and friends. Second NY here (most of the in laws have moved here) and definitely can’t complain. Ok- it’s a little cold :-)
That would be so very nice wouldn’t it
😱🥶
2026 will soooo need it! Thx.
Spotted at duty free. Let’s say … doubtful?
Man that’s rough. Reminds of NorCal 2018-20.
Hang in there !
Lab workshop today: Molecular Dynamics ! The nucleosome looks perfect for the season