Sjoerd Wanrooij

Super excited to present out work at @mitotalks.bsky.social this Thursday!! Hope to see you there!

We talk a lot about mitochondrial stress, but how about how do they keep themselves balanced? Good thing our speaker
@nieminm.bsky.social knows everything about that, and will tell all on the next MITOtalk. Usual time and place. See you there?

Join our Cloud HD Video Meeting Zoom is the leader in modern enterprise cloud communications.

The link sent on tuesday is not working. Please use this link instead: psu.zoom.us/j/92540254861

Travelling to the future again. This thursday, we will be nosy and learn about mitochondria and their friendships.

Tomorrow. See you there?

Thinking about remodeling? Mitochondria do that too... and our speaker knows all about it.
This thursday, usual time and place.
See you there?

5 years of MITOtalks!

Feels like it was yesterday when @wanrooij20.bsky.social
and @nunoraimundo.bsky.social
opened the first MITOtalk to introduce
@frezzalab.bsky.social.

But it turns out FIVE YEARS have passed. That's 57 MITOtalks, 44 MITOchats, 6000+ followers.

Onwards and upwards!

The MITOscience of tomorrow is back.
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?

In case you overloaded mitochondria and peroxisomes during your holidays, know that they are talking about it... and our speaker Peter Kim overheard the conversation.
This thursday, usual time and place. See you there?

MITOchats are all about early career researchers and - of course - mitochondria! Join us tomorrow for three short talks delivered by Julia Riley @joulesriley.bsky.social, Eleonora Stronati, and Joan Blanco-Fernandez @joanblanco.bsky.social. See mitotalks.org for zoom link.

the MITOscience of tomorrow is back.

Last MitoTALK of 2025!

Ewa Warczak
@bomba_ewa

From Synthesis to Stability: Understanding the Lifecycle of Mitochondrial Proteins

Thursday, December 4, usual time.

See you there?
mitotalks.org

Thanks for coming, Björn!

We’re live!
The Department of Medical Biochemistry & Biophysics at @umeauniversitet.bsky.social explores life at the molecular level: infection and structural biology, gene expression, mitochondria, neurodegeneration & biophysics for climate change.
Follow for updates & collaboration!
#Biochemistry

How's your juggling act? Mitochondria also have one, and the MITOtalk this week will be all about it.
See you there?

Our new preprint is out 🥳🥳🥳

Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence?

👇

Postdoctoral fellowship (2 years) to study proteins that maintain mitochondrial DNA The Department of Medical Biochemistry and Biophysics is offering a postdoctoral scholarship within the project "Signaling of mitochondrial DNA instability". The scholarship is full-time for two year

🚨 Postdoc position open!
Join us at Umeå University to study proteins that maintain mitochondrial DNA stability.
2-year fellowship | International research environment | Apply now!
🔗 umustipendie.varbi.com/en/what:job/...
#Postdoc #Mitochondria #Biochemistry #AcademicJobs

Who wouldn't want a good workout for their mitochondria to be fit?? Learn with our speaker Kostas Tokatlidis how to get them fit!
We would tell you the time and place, but you know where to find this MITOtalk on October 2nd. Right?

The future is visiting again! We are seeking applicants for the 7th season of MITOchats. Deadline for submission is October 17th. Visit www.mitotalks.org for details or submit your application at forms.gle/5D6vWE92yYCi...

(2/2) And from January 2026 onwards:

Jan 08 Peter Kim
Feb 05 Robin Klemm
March 05 Natalie Niemi
April 02 Henry Higgs
May 07 Eija Pirinen
June 04 Heidi McBride

usual time and place. See you there?

Now that the summer season is over, it's time for some MITObusiness. (1/2)

Oct 02 Kostas Tokatlidis
Nov 06 Hiromi Sesaki
Dec 04 Ewa Bomba-Warczak

Today!!! See you there?

📢One week to go until our webinar with @mitotalks.bsky.social focussed on all things #mitochondria.

Register here: us02web.zoom.us/webinar/regi...

MITOtalks and FocalPlane features... Thursday 3 July 2025, 16:00 BST Image of Yuli Buckley - Fis1 regulates mitochondrial morphology, bioenergetics and removal of mitochondrial DNA damage Yuli Buckley (Case Western Reserve University School of Medicine) Image of Mireia Nager - Mitophagy is induced in human engineered heart tissue after simulated ischemia and reperfusion Mireia Nager (University Hospital of North Norway) Image of Dikaia Tsagkari - NHR-85 modulates mitochondrial and lipid homeostasis to protect against α-synuclein aggregation Dikaia Tsagkari (University of Crete) journals.biologists.com/jcs/issue/138/9 QR code FocalPlane and MITOtalks logo

Our next #FocalPlaneFeatures webinar is in collaboration with @mitotalks.bsky.social. For this special webinar, Nuno Raimundo & @wanrooij20.bsky.social have selected 3 talks from @jcellsci.bsky.social's Special Issue: Cell Biology of Mitochondria.
📅3 July
focalplane.biologists.com/2025/06/09/m...

The low endoribonuclease activity and lack of rNMP preference of human mitochondrial topoisomerase 1 protect against ribonucleotide-dependent deletions Abstract. The incorporation of ribonucleotides (rNMPs) into the nuclear genome leads to severe genomic instability, including strand breaks and short 2–5 b

Our newest paper on mitochondrial Topoisomerase 1 shows that Top1mt has only weak endoribonuclease activity and it therefore does not often generate deletions at incorporated ribonucleotides. This helps explain why ribonucleotides are tolerated in mtDNA. Read more:
academic.oup.com/nar/article-...

MITOtalks and especially MITOchats have been playing with time travel. This week, instead of bringing the future over, we will get there faster: our speaker will tell us all about a mitochondrial progeria syndrome. Usual time and place.

This thursday, we talk supply logistics, with lots of energy.

Two mtDNA papers of ours in one PNAS issue:
#1 on the Y951N patient mutation of PolG, heroically spear-headed by Josefin Forslund
#2 revealing surprising dNTP imbalance & subsequent mtDNA depletion in RRM2B-deficient mice, a great collaboration with the Chabes lab
www.pnas.org/toc/pnas/122...

Good science from Josefin Forslund and our team:
The POLγ Y951N patient mutation disrupts the switch between DNA synthesis and proofreading, triggering mitochondrial DNA instability | PNAS www.pnas.org/doi/10.1073/...

Postdoctoral fellowship (2 years) to study mitochondrial DNA stability

Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share!
www.umu.se/en/work-with...