Mikus Puriņš

Bridging the pyridine-pyridazine synthesis gap by skeletal editing Pairs of heterocycles differing by a single constitutive ring atom can exhibit stark differences in the retrosynthetic disconnections available for their preparation. Such a synthesis gap is exemplifi...

It’s pyridazine day at @science.org as two groups make double-N hexagonal rings! @levinchem.bsky.social and @mikusp.bsky.social do it by orchestrating an N-for-C swap in pyridines

chemsky 🧪

www.science.org/doi/10.1126/...

Congrats!