Aging-US

🔆 #PaperSpotlight:
A new #research paper was #published on March 3, titled “P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts.” @olddominionu.bsky.social

🔗 doi.org/10.18632/agi...

#aging #quote #senescence #IPF #lungs #p38 #oa

🎥 #AgingShort:
Abstract #video about this #research paper #published in Volume 18, titled “P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts.” @olddominionu.bsky.social

🔗 doi.org/10.18632/agi...

#aging #PaperSpotlight #IPF #oa

Using Machine Learning to Identify Senescence-Inducing Drugs for Resistant Cancers - Aging-US Research Treating aggressive cancers that do not respond to standard therapies remains one of the most significant challenges in oncology. Among these are basal-like breast cancers (BLBC), which lack hormone r...

✅ Read our #blog post about the #research paper, titled "SAMP-Score: a morphology-based machine learning classification method for screening pro-senescence compounds in p16 positive cancer cells."

#Summary ⬇️
aging-us.org/2025/12/usin...

#aging #cancer #machinelearning #publishing

Behind the Study: Gut Microbiome Links to Age-Related Traits and ApoM Protein | Aging-US YouTube video by Aging-US

🧬 #BehindtheStudy:
Federica Grosso presents the #research paper, "Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels.”

🎥 www.youtube.com/watch?v=qYg4...

#aging #interview #gutmicrobiome #oa #publishing

Aging-US papers #published since 2009 can be found in our #archive:

www.aging-us.com/archive

#openaccess #peerreviewed #journalpublication #publishing #research

D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice | Aging Aging | doi:10.18632/aging.206358. Naidu B. Ommi, Dwight A. L. Mattocks, Mark C. Horowitz, Sailendra N. Nichenametla

#PaperoftheDay: "D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice"

DOI ⬇️
doi.org/10.18632/aging.206358

#aging #research #openaccess #peerreview #publishing

EDITORS’ CHOICE: Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV - Aging-US Research In this study, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV" and published in Volume 18 of Aging-US, researchers used single-cell RNA sequencing t...

⭐ #EditorsChoice:
“Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV.”

🔗 Read the Editors’ Choice feature:
aging-us.org/2026/03/edit...

#aging #research #HIV #COVID #Tcells #openaccess #openscience #peerreviewed #journal #publishing #meded

A Common Aging Pattern: Changes in RNA Splicing and Processing Across Human Tissues - Aging-US Research As we age, every tissue in the body undergoes gradual molecular changes. A long-standing question in aging research is whether these changes follow common patterns across tissues or whether each tissu...

✅ Read our #blog post about the #research paper, titled "A combination of differential expression and network connectivity analyses identifies a common set of RNA splicing and processing genes altered with age across human tissues."

#Summary ⬇️
aging-us.org/2026/01/a-co...

#aging

Behind the Study: Social and Cardiovascular Risk Factors in Older Adults with Prediabetes | Aging-US YouTube video by Aging-US

🧬 #BehindtheStudy:
Dr. Leonard Egede, Dr. Rebekah Walker, and Dr. Obinna Ekwunife @ubuffalo.bsky.social discuss “Longitudinal relationship between social and CVD risk factors in older adults with prediabetes: the HRS 2006-2016.”

🎥 www.youtube.com/watch?v=1MST...

#aging #interview #prediabetes

Exploring Impact Journals: Advancing Biomedical Science for Life Without Disease | Aging-US YouTube video by Aging-US

The mission of Impact Journals (Aging's publisher) is to provide #scientists with the opportunity to share their exceptional #discoveries, to offer #services that enable the rapid dissemination of #results, and more ...
www.youtube.com/watch?v=CFIJ...

#aging #journal #oa #video #youtu

Aging-us.org - Research Aging-US.org features weekly articles describing new and trending research papers published by Aging (Aging-US).

🌐 Visit Aging-US.org to read #blog synopses of new and trending #research papers published by Aging-US.
aging-us.org

#aging #longevity #openaccess #science #medicine #medEd #OA

📢#CallforPapers:
Aging-US is honoring @Blagosklonny with a special #collection.

Submit your #research, reviews and perspectives on mTOR, rapamycin, #aging, cancer & more.

📅 Deadline: May 31, 2026

🔗 Submission Details:
www.aging-us.com/mikhail-blag...

#agingresearch

Behind the Study: Validating Electronic Frailty Index in National Health System | Aging-US YouTube video by Aging-US

🧬 #BehindtheStudy:
Dr. Fabienne Hershkowitz Sikron discusses the #research paper, titled “Development and validation of an electronic frailty index in a national health maintenance organization.”

🎥 www.youtube.com/watch?v=pc9_...

#author #interview #frailty #health #oa #publishing

📰 Read the latest #pressreleases published by Aging-US:

www.aging-us.com/news-room/pr...

#aging #research #science #data #OA #ebm #news #press

Aging’s Special Collection on Eye Disease:

www.aging-us.com/special-coll...

#aging #research #science #meded #openaccess #publications #publishing #collection

For #authors:
Please review our editorial policies and publishing standards:

www.aging-us.com/editorial-po...

#publishing #aging #policy #guidelines #openaccess #peerreviewed #journal #publication

P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts | Aging Aging | doi:10.18632/aging.206357. Shan Zhu, Jennifer Q Zhou, Kan Wang, Ming-lei Guo, Yan Y Sanders

#PaperoftheDay: "P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts"

DOI ⬇️
doi.org/10.18632/aging.206357

#aging #research #openaccess #gerontology #peerreview #journal #publishing

The Longevity & Aging Series invites Aging-US #researchers to discuss their #longevity and #aging papers.

Watch the latest #episodes from the #series ⬇️
www.aging-us.com/longevity

#longevityandaging #openaccess #peerreview #interviews #videos #authors

How Exosomes Spread Aging Signals and Could Support Anti-Aging Research - Aging-US Research As the global population grows older, understanding what drives the aging process is becoming increasingly important. Diseases like Alzheimer’s, cardiovascular conditions, and cancer are more common w...

✅ Read our #blog post about the #research paper, "Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures."

#Summary ⬇️
aging-us.org/2025/09/how-...

#aging #exosomes #proteomics #publishing

🚨 Ready to #publish with us?

Submit your #paper online with Aging-US today ⬇️

aging.msubmit.net/cgi-bin/main...

#aging #research #journal #peerreviewed #openaccess #openscience #longevity #lifespan #healthspan #gerontology #meded

#PaperoftheDay: "Aging retinal pigmented epithelium: omics-based insights into vision decline"

DOI ⬇️
doi.org/10.18632/aging.205914

#aging #research #openaccess #gerontology #peerreview #journal #publishing

Tictock: A Single-Cell Clock Measures Immune Aging in Viral Infections - Aging-US Research Aging reshapes the immune system in two fundamental ways: it alters the proportions of different immune cell types circulating in the blood, and it induces molecular changes within each individual cel...

✅ Read our #blog post about the #research paper, titled "Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV."

#Summary ⬇️
aging-us.org/2026/03/tict...

#aging #HIV #COVID #Tcells #oa #openscience #peerreviewed #journal #publishing #meded

Behind the Study: Rapamycin’s 1-Year Impact on Healthspan—PEARL Trial Results | Aging-US YouTube video by Aging-US

🧬 #BehindtheStudy:
Dr. Stefanie Morgan joins Dr. Robert Dudley from AgelessRx to discuss a #research paper she co-authored in Volume 17, Issue 4, titled “Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results.”

🎥 www.youtube.com/watch?v=2qlI...
#aging #interview

How Long-Term Social Connection Supports Brain Health and Memory in Aging - Aging-US Research As people age, it is common to experience some memory lapses or slower thinking. Although this is often a normal part of aging, it can still affect a person's quality of life. Scientists have been inv...

✅ Read our #blog post about the #research paper, "The impact of long-term social housing on biconditional association task performance and neuron ensembles in the anterior cingulate cortex and the hippocampal CA3 region of aged rats."

#Summary ⬇️
aging-us.org/2025/10/how-...

#aging #oa #publishing

Aging’s Special Collection on Diet:

www.aging-us.com/special-coll...

#aging #longevity #diet #research #science #meded #openaccess #publications

HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis | Aging Aging | doi:10.18632/aging.206008. Hao Zhang, Bing Han, She Tian, Yongjun Gong, Liwen Chen, Li Liu

#PaperoftheDay: "HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis"

DOI ⬇️
doi.org/10.18632/aging.206008

#aging #research #openaccess #gerontology #peerreview #journal #publishing

🔆 #PaperSpotlight:
A new #research perspective was #published on February 24, titled “A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived.”

🔗 doi.org/10.18632/agi...

#aging #quote #lifespan #gerontology

🎥 #AgingShort:
“A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived.”

🔗 doi.org/10.18632/aging.206356

#aging #PaperSpotlight #lifespan #gerontology #research #perspective #openaccess #publishing #video

Longevity & Aging Series (S3, E5): Dr. Andres Cardenas | Aging-US YouTube video by Aging-US

🧬 Longevity & Aging Series (S3, E5):
Dr. Andres Cardenas discusses:
“Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey.”

🎥 youtu.be/A1I6qoVwkfM

#aging #research #oa #series #longevity #video #interview

Epigenetic Changes in Sperm May Explain Association Between Paternal Age and Autism Risk - Aging-US Research While maternal health has traditionally been central to research on pregnancy and child development, there is growing recognition that paternal factors also play a role, particularly the father’s age....

✅ Read our #blog post about the #research paper, "Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring."

#Summary ⬇️
aging-us.org/2026/02/epig...

#aging #TrendingWithImpact #autism #sperm