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Effie Bastounis

@effiebastounis

Junior research group leader in Tuebingen, bioengineer, infection biomechanics, host-pathogen interactions, fav bug: Listeria, quantitative biology, yoga, backpacking trips

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17.11.2024
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Latest posts by Effie Bastounis @effiebastounis

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Listeria-infected macrophages promote biomechanical alterations in endothelial cell monolayers for transmigration Intracellular pathogens like Listeria exploit macrophages to cross endothelial barriers and spread systemically. Muenkel et al. show that exposure to infected macrophages weakens contractile forces wi...

I'm excited to share our paper on how infected #macrophages promote #biomechanical alterations in #endothelia to transmigrate, published in @cp-cellreports.bsky.social! Thanks to all contributors, @sergemostowylab.bsky.social and @cmfi.bsky.social for the support. Here: www.cell.com/cell-reports...

25.02.2026 13:22 πŸ‘ 17 πŸ” 6 πŸ’¬ 0 πŸ“Œ 3
2026 Ascona Thematic Meeting

Very excited for the upcoming "Mechanobiology of Infection" meeting we are organizing with Alexandre Persat and Daria Bonazzi. Thanks to @biophysicalsoc.bsky.social Society for their support - looking forward to it! Abstract submission and registration here: www.biophysics.org/meetings-eve...

11.02.2026 15:11 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Cell Bio 2023-An ASCB|EMBO Meeting Network, learn, and collaborate with top cell biologists from around the globe.

Thrilled to organize the β€œPhysical Cell Biology of Immunity & Infection” subgroup at Cell Bio 2025 – ASCB/EMBO with @hawa-racine.bsky.social, @jaumouillelab.bsky.social, Marcus Taylor & Shalini Low-Nam. Seeking exciting interdisciplinary speakers! Abstract deadline: Sept 3 www.ascb.org/cellbio2025

18.08.2025 10:58 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2

We’re hiring! A PhD position (E13 TV-L, 65%) is available at @cmfi.bsky.social @unituebingen.bsky.social. The DFG-funded project explores how mechanical forces shape intracellular bacterial infections, focusing on Listeria. Details & application: www.euraxess.de/jobs/366585. Start: ASAP!

06.08.2025 09:20 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Great work from @calinacopos.bsky.social lab on #migration of #cell trains! Excited to have contributed some of my old #Dictyostelium data to the modelling work!

23.05.2025 12:14 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Looking for a method to characterise cell #motility and #ERK signalling waves?
Check out our STAR protocols paper:
star-protocols.cell.com/protocols/41...

Thanks for the great work Julio Cesar Sanchez-Rendon & @effiebastounis.bsky.social!

#protocol #epithelia #FRET #singlecell #imaging

13.05.2025 12:05 πŸ‘ 9 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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How is extrusion of infected host cells related to ERK (extracellular signal-regulated kinase) activity?

Hi, I’m @hundsdorfer.bsky.social from the @effiebastounis.bsky.social lab. Let’s follow the recent development of bacterially-infected cell extrusion & mechanochemical ERK activity waves.

30.03.2025 07:57 πŸ‘ 27 πŸ” 9 πŸ’¬ 2 πŸ“Œ 1
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The study of @hundsdorfer.bsky.social et al. on ERK waves coordinating the #biomechanical competition between #epithelial #cells resulting in infected cell extrusion is out: doi.org/10.1016/j.ce.... Thanks to all contributors, DFG, @cmfi.bsky.social & @Serge for #Shigella & #zebrafish experiments!

21.01.2025 08:07 πŸ‘ 17 πŸ” 5 πŸ’¬ 1 πŸ“Œ 4
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Delighted that our review on modeling of #endothelial and #epithelial #cell monolayer #biomechanics is now published in @cp-trendscellbio.bsky.social: doi.org/10.1016/j.tc...! Thanks to all contributors and to DFG, UniversitΓ€t TΓΌbingen, @cmfi.bsky.social for the support!

21.01.2025 07:32 πŸ‘ 28 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0
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Happy to share our paper describing StretchView, an accessible cell-stretching device compatible with automated live-cell videomicroscopy: doi.org/10.1002/advs...! A great collaboration with the Constantinou lab TU Braunschweig. Thanks to DFG, UniversitΓ€t TΓΌbingen, @cmfi.bsky.social for supporting!

13.01.2025 14:41 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0