Alexander Lorenz

MSc by Research: Does the mis-regulation of the meiotic HORMA-domain protein induce genome instability? at University of Aberdeen on FindAPhD.com PhD Project - MSc by Research: Does the mis-regulation of the meiotic HORMA-domain protein induce genome instability? at University of Aberdeen , listed on FindAPhD.com

The other one on how the misregulation of a key meiotic factor might affect genome stability tinyurl.com/pjxrvur9

MSc by Research: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen on FindAPhD.com PhD Project - MSc by Research: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen , listed on Find...

I am offering two MSc by Research opportunities in my laboratory (self-funded!), one on the human-pathogenic yeast Candidazyma auris tinyurl.com/ys8zexbv

Just arrived in Newcastle for the @gensocuk.bsky.social summer studentship workshop, looking forward to interesting science from early-career researchers #genetics

A cytological framework of female meiosis in Arabidopsis Female and male meiosis often differ in many aspects, such as their duration and the frequency as well as the positioning of crossovers. However, studying female meiosis is often very challenging and ...

Six more years—plus a lot of blood, sweat, and tears—later, we are thrilled to finally share it: a cytological framework of female meiosis in Arabidopsis!

www.biorxiv.org/content/10.1...

Very happy to have our preprint published in Microbiological Research now doi.org/10.1016/j.mi..., we had additional help from Steven during the revision to get this over the line @chitinette.bsky.social @theafg.bsky.social @uniofaberdeen.bsky.social

The Provocateurs: Genetics Bingo - The Stand Comedy Club The Provocateurs: Genetics Bingo Hosted by comedian Susan Morrison. Ear wax – for some people, it is wet and smelly, for others it is dry and flaxy. And not ...

Ready to shout BINGO! and learn something mind-blowing in the process? Join @genotripe.bsky.social for Genetics Bingo at the @edfringe.bsky.social, play actual bingo and find out some wild genetic facts!

📅 12th August
📍 The Stand 2

www.thestand.co.uk/performance/...

Ancient genomes: perspectives on human biology and medicine | Genetics Society It is our great pleasure to invite you to participate in the Autumn Meeting of the Genetics Society. This meeting will provide a unique forum to network and socialise with a wide cross-section of the ...

We’ve got some good news! The deadline to submit abstracts for our “Ancient #Genomes: Perspectives on Human Biology and Medicine” meeting has been extended to 31 July 2025. So if you were thinking about submitting, there’s still plenty of time!

genetics.org.uk/events/ancie...

My MSc students are getting to work ☺️

Join us for our Anniversary Day and hear from:

Prof Josephine Pemberton (Genetics Society Medal)
Prof Kathy Niakan (Mary Lyon Medal)
Prof Gregory Radick (Haldane Lecture)
Prof Richard Durbin (Genomics keynote)
Rosie Parkin & Eldrian Tho (Student talks)

Registration: genetics.org.uk/events/genet...

Welcome to Belfast! We're thrilled to kick off our spring conference: "Epigenetics: from mechanisms to diseases".

Get ready for groundbreaking science and inspiring talks! #Epigenetics2025

We have a complete program !

meiosis.cornell.edu/mayosis2025/...

The #Mayosis25 seminar series will open with a tribute to Scott Hawley by @jeffsekelsky.bsky.social.

Congrats to all the selected speakers and we look forward to hearing about your fantastic science !

#Meiosis4ever

Apparently my BSc project students enjoyed their time in my lab as much as I enjoyed supervising them

Cartoon of a metabolically engineered yeast cell recycling carbon in a spaceship

My lab @bokuvienna.bsky.social has an opening for a PhD on Synthetic Single Carbon Assimilation in Yeast.
Find details here www.circularbioengineering.at/jobsprogram2 - PhD 2.1 if you consider joining us within the Cluster of Excellence Circular Bioengineering

The truth is that the scientific process is horribly inefficient and wasteful. But the solution is NOT cutting funds and it’s NOT top down guidance of what should be studied. Instead, we should revolutionize how we publish and improve peer review.

Thanks for your message. We don't know enough about biocide selection in C. auris and how this affects its genetics and biology, so hard to tell.

we observe that these variants show little changes in biochemical and ultrastructural features of the cell wall, and that the moderate fitness trade-offs ultimately do not impinge on the pathogenicity potential of C. auris (in contrast to what has been reported for Candida albicans). 4/4

we show that these variants produce cross-resistance to other echinocandin drugs but moderate collateral sensitivity to other antifungals and cell wall stress (fitness trade-offs) 3/n

we show that caspofungin-resistant isolates harbour SNPs in the expected target gene FKS1 (FKS1-S639P and FKS1-S639Y variants) 2/n

In this manuscript we show that a caspofungin-sensitive C. auris clade II isolate can develop resistance against caspofungin during in vitro evolution under drug pressure (similar approaches were previously unsuccessful) 1/n

In vitro evolution of caspofungin resistance in Candidozyma auris via FKS1 hotspot I mutations results in moderate fitness trade-offs but no reduction in virulence Resistance to echinocandins in the recently emerged pathogen Candidozyma auris (previously known as Candida auris ) poses significant clinical challenges. This study reports the in vitro evolution of ...

I posted this preprint to bioRxiv already before the holiday break and didn't have time to talk about it here yet www.biorxiv.org/content/10.1... 🧬🧫🔬 Work from two of my PhD students, Zoe and Sakinah, with help from Yixin & @chitinette.bsky.social

Only a few days left to apply!

Happy new year everyone!

We are please to announce the return of MAYosis in 2025!

Every Wednesday in May at 4pm CET, come hear the latest #meiosis4ever stories!

Abstract sub deadline: March 8 (end of day wherever you are)

meiosis.cornell.edu/mayosis2025/

Project at Aberystwyth University: Decoding Heat Tolerance At Flowering: Using Multi-omics Approaches to Unlock Crop Resilience at University of Reading on FindAPhD.com PhD Project - Project at Aberystwyth University: Decoding Heat Tolerance At Flowering: Using Multi-omics Approaches to Unlock Crop Resilience at University of Reading, listed on FindAPhD.com

PhD Opportunity! Apply multiomics approaches to uncover how plants maintain fertility under heat stress. We're looking for enthusiastic applicants passionate about plant science! 🌾🧬🔬
Apply: bit.ly/TempResilien...
Deadline: 03.02.2025
#PhDPosition #PlantScience #CropImprovement

Programme Leader Track - MRC Laboratory of Medical Sciences Programme Leader Track appointments are an open-ended contract, which comprises a six-year advanced career development scheme after which you will be considered for promotion to Programme Leader.

@mrc-lms.bsky.social is hiring! Are you looking to start your own research group? Come & join us!

Fantastic research, wonderful facilities & super supportive colleagues. Deadline 13th Jan.

Get on it!

lms.mrc.ac.uk/work/vacanci...

EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen on FindAPhD.com PhD Project - EASTBIO: Harnessing Transposon Mutagenesis to Dissect Antifungal Drug Resistance in the Fungal “Superbug” Candidozyma auris at University of Aberdeen , listed on FindAPhD.com

There is competitive #PhD funding for 4 years (eligibility criteria apply) to do a project on the human pathogen Candidozyma (Candida) auris dissecting the genetic basis of its antimicrobial resistance #AMR www.findaphd.com/phds/project... - pls repost

The Makrantoni lab inflammation-research.ed.ac.uk/research/inf... at the University of Edinburgh has a fully-funded 4-year PhD position to study genome plasticity in #Candida #PhD International/EU candidates who are not studying at Edinburgh only (see flyer for details)

Very happy to receive a Wellcome CDA! The award will fund my lab for a whopping 8 years, allowing us to dissect force-sensing at the kinetochore-microtubule interface in depth using structural methods. We are currently looking for a postdoc: qmul-jobs.tal.net/vx/candidate... Please apply or repost

I'm still buzzing after the @gensocuk.bsky.social meeting.

Here are all 25 talks summaries together

#SciArt #TEsky

go.bsky.app/D63c48C

Experimental results showing DNA break formation by purified SPO11 protein. Above is an image of an electrophoresis gel, below is a graph showing quantification of the DNA cleaving activity

Hi Bluesky. For my first post, I'd like to advertise the latest preprint from my lab, describing at long last our reconstitution of SPO11-dependent double-strand break formation from purified recombinant proteins. Outstanding work from PhD student Zhi (Zack) Zheng.