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Martin Kaiser

@mymkaiser

Haemato-oncologist and myeloma researcher; genetics, imaging and more for patient-centric care. Vice-chair UK NCRI Myeloma Trials. EHA European Affairs. Interested in access and HTA. Academic nomad.

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29.10.2023
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Latest posts by Martin Kaiser @mymkaiser

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It is interesting whether this consumer ens***tification will lead to stronger public discontent than people currently believe.

Some people think the Soviet Union broke apart not because they had an operating space station or nuclear weapons - but because consumer goods supply got worse and worse.

20.02.2026 08:37 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
A screenshot of a tech magazine describing PS6 delays because of memory shortages

A screenshot of a tech magazine describing PS6 delays because of memory shortages

A screenshot of a tech magazine describing hard drive shortages for 2026, 2027, 2028

A screenshot of a tech magazine describing hard drive shortages for 2026, 2027, 2028

Very few things seem to lead to public disquiet at the moment.

One wonders whether the below may.

Panem et circensis.

18.02.2026 05:14 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Interesting this is highlighted the same day as the research on antibiotic resistance in E. Coli, which seems to suggest that dormant microbes are not the ones conferring resistance. Working in an incurable cancer, I wonder whether we will see the same here. We still hardly understand proliferation.

08.02.2026 10:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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On the balance of knowledge - Nature Reviews Immunology Ruslan Medzhitov shares his thoughts on the balance between generating data and developing theories in immunology, with a focus on exploring the rules that govern complex systems.

'Empirical data and the theories that make sense of them are the twin pillars of scientific progress. When one pillar is raised much higher than the other, they cease to be good pillars.'
www.nature.com/articles/s41...

06.02.2026 07:39 πŸ‘ 17 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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The Fight For Slow And Boring Researchβ€”Asterisk As federal research funding shrinks, scientists are looking to other sources of support. Can they learn to sell their work without selling out?

Provocative! Not all scientists will want to hear this. I agree with many points. In parallel to emphasis on better communication, I hope we’ll begin conversations about maintaining integrity.
asteriskmag.com/issues/13/th...

24.01.2026 06:38 πŸ‘ 62 πŸ” 13 πŸ’¬ 2 πŸ“Œ 2
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X claims it has stopped Grok from undressing people, but of course it hasn’t It’s still easy to get Grok to edit photographs of real people into sexualized poses, despite X’s updated restrictions.

It’s a matter of time before Tesla automatically generates non-consensual images of people in revealing clothing as you drive past them.

15.01.2026 08:41 πŸ‘ 111 πŸ” 27 πŸ’¬ 4 πŸ“Œ 2

I know the proliferation of references to non-existent papers, powered by genAI, is getting less surprising and shocking but it doesn't make it any less potentially corrosive to the scholarly knowledge environment.

19.12.2025 17:37 πŸ‘ 964 πŸ” 97 πŸ’¬ 4 πŸ“Œ 5
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Challenging the concept of functional high-risk myeloma through transcriptional and genetic profiling Key PointsTrue functional high-risk MM is very uncommon when comprehensive clinical and molecular profiling is applied.High-risk GEP with standard-risk gen

Are 'unexpected' early relapses really unexpected in #myeloma ? Or a sign for need for wider implementation of and access to already diagnostic tests?

Challenging the concept of functional high-risk myeloma through transcriptional and genetic profiling url: ashpublications.org/blood/articl...

01.12.2025 07:06 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I don’t know if anyone else notices or cares, but when I see a presentation in which the speaker uses obviously generated-AI images to illustrate their slides, it makes me immediately less confident in whatever other content they’re presenting.

28.11.2025 15:07 πŸ‘ 12381 πŸ” 2021 πŸ’¬ 212 πŸ“Œ 301
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Meet the AI workers who tell their friends and family to stay away from AI When the people making AI seem trustworthy are the ones who trust it the least, it shows that incentives for speed are overtaking safety, experts say

Meet the AI workers who tell their friends and family to stay away from AI

22.11.2025 16:13 πŸ‘ 210 πŸ” 96 πŸ’¬ 14 πŸ“Œ 21
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Evaluating the real-world value of daratumumab addition to multiple myeloma induction therapy by real-world minimal residual disease assessment and extended genetic profiling Daratumumab, bortezomib, thalidomide, and dexamethasone (Dara-VTd) is the current standard of care in Europe based on the CASSIOPEIA study, which demonstrated improved depth of response and progressio...

Real-world data is a hot topic with medical regulators and payers in oncology. Here is our analysis comparing a change in induction regimens in multiple myeloma in a public healthcare system, using real-world MRD measurement.

www.clinical-lymphoma-myeloma-leukemia.com/article/S215...

16.11.2025 07:10 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Largest study of its kind shows AI assistants misrepresent news content 45% of the time – regardless of language or territory An intensive international study was coordinated by the European Broadcasting Union (EBU) and led by the BBC

Yet again, we can't afford to let LLMs become a source of epistemic grounding for society.

24.10.2025 05:21 πŸ‘ 2198 πŸ” 924 πŸ’¬ 25 πŸ“Œ 58
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Sir David Spiegelhalter: Regulation in an age of personalised medicine The internationally renowned expert in the calculation and communication of risk and statistics, Sir David Spiegelhalter, discusses the concept of a β€˜preference zone’ to frame the demands of safety, e...

Very nice reflection on risk and personalisation of medicine in context of regulation

www.gov.uk/government/n...

11.10.2025 17:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Anduril and Palantir battlefield communication system has deep flaws, Army memo says The much-needed modernization of the U.S. Army's battlefield communications network being undertaken by Anduril, Palantir and others is rife with "fundamental security" problems and vulnerabilities, and should be treated as a "very high risk," according to a recent internal Army memo.

Doesn’t sound ideal.

"We cannot control who sees what, we cannot see what users are doing, and we cannot verify that the software itself is secure," the memo says.

www.reuters.com/business/aer...

04.10.2025 19:05 πŸ‘ 247 πŸ” 93 πŸ’¬ 16 πŸ“Œ 8

"Researchers recruited to work in the UK have to fund a Β£1,035 annual ο»Ώimmigration health surcharge, which must be paid in full in advance, as well as up to Β£1,519 in visa fees. For a family of four, the upfront costs can total almost Β£30,000."

12.05.2025 10:05 πŸ‘ 28 πŸ” 21 πŸ’¬ 2 πŸ“Œ 3
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🧬 Some promising novel candidates for therapeutic inhibition included:
β€’ BAFF-R and CD39 in HL
β€’ CD25 in MM
β€’ CD27 in CLL
β€’ CD80/86 in DLBCL
β€’ CCR2 in FL and MZL

16.04.2025 11:52 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Mendelian randomization of immune cell phenotypes to discover potential drug targets for B-cell malignancy - Blood Cancer Journal Blood Cancer Journal - Mendelian randomization of immune cell phenotypes to discover potential drug targets for B-cell malignancy

We are excited to announce our latest publication in #BloodCancerJournal of our Two-Sample MR analysis to investigate causal relationships between 446 immune cell traits and 6 B-cell malignancies

πŸ“„ www.nature.com/articles/s41...

#cancer #genetics #Bcell #bloodcancer #drugdiscovery #MR

16.04.2025 11:52 πŸ‘ 4 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Funny how this hypothetical talk of "optimizing" never considers traits like kindness, decency, generosity of spirit... It's always "what does my baby need to get ahead?"

06.04.2025 09:51 πŸ‘ 134 πŸ” 28 πŸ’¬ 9 πŸ“Œ 0
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Great comment by @sarahoconnorft.ft.com -- I shared some reflection at the start of the year. To me a revaluation of social status is necessary and potentially a reconfiguration of social organisation away from occupational silos.

www.trfetzer.com/generational...

25.03.2025 13:12 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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No evidence for Peto’s paradox in terrestrial vertebrates | PNAS Larger, longer-lived species are expected to have a higher cancer prevalence compared to smaller, shorter-lived species owing to the greater number...

Peto's Paradoxβ€”that cancer does not increase with body size of mammalsβ€”was wrong.
A new, comprehensive study of 263 species documents higher cancer prevalence with increasing body mass. Some large animals (e.g. elephants) have some built-in genetic adaptations
www.pnas.org/doi/10.1073/... @pnas.org

25.02.2025 18:15 πŸ‘ 311 πŸ” 75 πŸ’¬ 3 πŸ“Œ 10
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Advanced imaging for earlier diagnosis and morbidity prevention in multiple myeloma: A British Society of Haematology and UK Myeloma Society Good Practice Paper The BSH Guidelines Official Podcast Β· Episode

A pleasure to do this British Society of Haematology podcast on advanced imaging in myeloma for earlier diagnosis and morbidity prevention with Dr Ceri Bygrave.

open.spotify.com/episode/1JAq...

24.02.2025 22:08 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Meanwhile, some voting districts (Berlin-Mitte, of all !πŸ™„) did not manage to send out election materials to voters abroad on time. Certainly not an important feature given the high % of votes casted (which is great) but still disappointing re active democratic participation.

24.02.2025 06:49 πŸ‘ 22 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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The inverse correlation between articles bemoaning the existential plight of the German economy, and its stock market, is a wonder to behold

18.02.2025 15:16 πŸ‘ 25 πŸ” 7 πŸ’¬ 3 πŸ“Œ 3
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Can Germany’s economy stage an unexpected recovery? The situation is dire, but there are glimmers of hope

Amazing historical quote in the Economist: 'In part owing to the East German government’s industrial policy in the 1980s, ..., the region (Saxony) has become Europe’s largest maker of microelectronics'
Fantastic DLF podcast on similar topic ('Neuland')
www.economist.com/finance-and-...

31.01.2025 09:21 πŸ‘ 6 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Literally just cleaned survival data for a Sunday R analysis...

26.01.2025 11:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Why this China-made BYD Shark pickup is drawing attention in the global truck market BYD has not announced plans to sell the Shark in the U.S., but it has entered countries such as Mexico, where GM, Ford and Toyota sell pickup trucks.

China wants in on the pedestrian and cyclist crushing game too.

26.01.2025 08:00 πŸ‘ 180 πŸ” 23 πŸ’¬ 6 πŸ“Œ 2

Which are also not covered for visiting students from EU funders (at least NHS fee not covered by @dfg.de ), making it comfy for junior researchers πŸ™ƒ

23.01.2025 08:32 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

If there's something we don't understand I assume transposons are responsible unless proven otherwise

18.01.2025 18:23 πŸ‘ 128 πŸ” 29 πŸ’¬ 16 πŸ“Œ 4

Did this a few years ago. Consider watching Wolf Hall as easy going prep. Knowing the names of the Henry VIII's wifes seemed to answer 50% of questions.

11.01.2025 12:16 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0