Kirsty McMillan

Exciting conference alert! The 93rd Biochemical Society Harden Conference will be on "Endosomal-lysosomal network dysfunction in neurodegeneration" on the South coast of England (1st to 4th of September 2026). Lots of speaker slots available from submitted abstracts so do come and join us!

Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation. Induced protein proximity offers powerful new routes to modulate protein fate. While proteolysis-targeting chimeras (PROTACs) promote degradation through E3 ligase recruitment, the converse principle-...

Our latest preprint is out!
We developed an inducible “RapTag” system that uses ENTAC to chemically recruit USP15 to the unstable protein CTLA4. This induced proximity stabilises and slows down the rapid lysosomal turnover of CTLA4.
@livuni-ismib.bsky.social
www.biorxiv.org/content/10.1...

Postdoctoral Research Associate - Grade 7 at University of Liverpool Explore an exciting academic career as a Postdoctoral Research Associate - Grade 7. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

We have an exciting 18 month postdoc position available in our new lab in Liverpool. If you have experience in primary cultures and are interested in Endosomal Biology and Neurodegeneration do take a look. Please repost and share. www.jobs.ac.uk/job/DMZ553/p...

We have an exciting 2 year postdoc position available in our department in the lab of Marisa Merino - please see advert attached!

Please contact Marisa for more details!

Repost and share as you wish!

Fantastic to have a session focused on astrocytes and share the stage with 3 excellent researchers at #BNA2025

Amazing opportunity here. Not only do the Grieve lab do amazing science, Adam is a super supportive PI and the research group are fantastic.

Remembering David Stephens (1971–2024) In the autumn of 2024, David Stephens, a prominent member of the UK cell biology community and a brilliant scientist, leader and mentor, passed away. With his pragmatism and natural authority, combine...

A great tribute to David Stevens, a terrific cell biologist and missed by so many of his friends and colleagues. As they say 'one of the good guys'. journals.biologists.com/jcs/article/...

I feel very honoured and excited to have received the @acmedsci.bsky.social #Springboard25 award 🎉 I would like to thank the Academy & reviewers for supporting our research into understanding the biological causes of Alzheimer’s disease. Position announcement soon 🙂 @livuni-ismib.bsky.social

Wellcome Connecting Science Molecular Neurodegeneration and Therapeutic Approaches Course dates: 23-27 June 2025 Location: Wellcome Genome Campus, UK Application deadline: 1 April Apply now

Last chance to apply for our course focusing on #genomics techniques appropriate for studying #neurodegenerative disorders! #MolNeuro25🧠

📅23-27 June 2025
⏰ Apply by 1 April

🗣️Keynote: Karen Duff, UK Dementia Research Institute
💰 Bursaries available to support with fees

📎bit.ly/40pSCSH
#NeuroSky

Research Associate: Dopaminergic neurons derived from iNPCs The Mortiboys Lab at The University of Sheffield is seeking a Research Associate to work on the differentiation of iNPCs into dopaminergic neurons using the iDA differentiation protocol

The Mortiboys Lab at The University of Sheffield is seeking a Research Associate to work on the differentiation of iNPCs into dopaminergic neurons using the iDA differentiation protocol. Closing date: 30th March.

www.dementiaresearcher.nihr.ac.uk/job/research...

Finally my first author preprint at Cullen's lab is out! Amazing collaboration with Kevin and @brettcollins.bsky.social where, by using dedicated proximity proteomics, Biochemistry, crystallography and structural prediction, we show new aspects of human Retromer complex acting as hub for RAB GTPases

The Role of the Endosomal System in Alzheimer’s Disease. at University of Liverpool on FindAPhD.com PhD Project - The Role of the Endosomal System in Alzheimer’s Disease. at University of Liverpool, listed on FindAPhD.com

I have a funded PhD studentship available to start in my new lab in 2025! If you are interested in Endosomal Biology, Astrocytes and Alzheimer’s Disease have a look:
www.findaphd.com/phds/project...

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