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15.04.2025 13:00
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If your attention span is modern-media-limited, this one slide is informative:
Are you someone with expertise in statgen who wants to impact therapeutic development? Come join my colleagues at #alnylam! You'll get a chance to work with interdisciplinary teams with a rapid timeline from discovery to proof of concept to clinic!
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Check out slides 128-173 from our R&D day and you'll see that genetic discovery and validation are a cornerstone to programs in the clinic or about to enter clinic.
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Labeling your axes and then explaining them slowly is perhaps the biggest bang for the buck you can get for making your slides more understandable.
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers] openrxiv.org 1/n
Thanks for the summary and perspective! I have a feeling "some new nightmare" may be a recurring theme for awhile...
Two contestants—a climate scientist and Punxsutawney Phil—compete in a game show called “Winter or Spring?” The host looks at the two contestants and says, “Thanks, Doctor, for those insights—now let’s hear from the groundhog.”
Today’s Daily Cartoon, by Sarah Kempa. #NewYorkerCartoons
If you care about citation stats (which you shouldn't) the fact that every author is more likely to cite their own papers in future work makes the citation stat ROI for adding authors quite good. Big consortia papers dominate citation indices for this reason.
New brain aging study is out today in Nature
The largest single-cell RNA seq dataset of mouse brain aging reveals incredible insights and could pave the way for future therapies to slow or manage the impacts of the aging process. 🧵 #studyBRAIN
Kitty riding a dolphin is about as informative for biology as genetic correlations 😀
It's not that it's for the rich, but for those with leverage to negotiate it. Seeing this a lot now, even in biotech.
"Calls for workers to return to the office while company leaders stay remote are particularly tough to swallow, given research showing that it’s the C-suite that is more ineffective from afar — not the rank and file."
nudging a figure by 1 millimeter within an MS Word version of your grant
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I was in denial initially when people explained to me how profit making practices could be worse at academic medical centers, and undermine cost conscious but high quality care. Disclaimer: I'm on the "for profit" side now, but feel more aligned with actually bringing patients new therapies.
in part because their chief financial officers have to worry about their bond ratings. (Perhaps also because they have boards filled with bankers rather than health care professionals and patients.) And the easiest way to increase your revenues is by becoming a monopoly."
TBH, this is the feeling I got as a trainee @uclahealth.bsky.social and @ucsfhealth.bsky.social: "More than a third of hospitals are for-profit, but many not-for-profit hospitals still focus on maximizing their revenues and margins...
Mercy of Gods was great, looking forward to the next in the series.
How it Unfolds in Audible has ok narrating, not as good a fit as the Expanse series narration.
Maybe I'll do a #scifi read/listen of the month? Appreciate new recs!
Recent is How it Unfolds, by James A. Corey, authors of #TheExpanse series. Space exploration meets Library of Babel. Most interesting is the idea of colonization being so hard that it'll take >>>1000s of tries.
Took me a couple of months in the evenings, but I finally finished @fchollet.bsky.social's DL in Python 2nd Ed book & colab notebooks. Very useful perspectives, nicely annotated code, and a useful entry point into many applications of #DeepLearning.
I started following you when I transferred contacts from my X account over, then you posted this, and now 80% of my "discover" feed is cats... :D
