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Peter Bellotti

@peterbellottti

Eppur si muove! Organic chemist and bookworm - πŸ“NYC

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19.11.2024
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Latest posts by Peter Bellotti @peterbellottti

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Suprematism, by Nikolai Suetin, 1920-21, πŸ“Έ by @tiltoncreative

22.02.2026 16:24 πŸ‘ 9970 πŸ” 2274 πŸ’¬ 65 πŸ“Œ 112
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Inverse Molecular Design for the Discovery of Organic Energy Transfer Photocatalysts: Bridging Global and Local Chemical Space Exploration The discovery of new organic photocatalysts (PCs) for energy transfer (EnT) catalysis remains a significant challenge, largely due to the vast and underexplored chemical space and the delicate balance...

Thrilled to share our hybrid inverse design strategy for discovering organic photocatalysts, now published in @JACS: Accelerating EnT catalyst discovery by bridging generative modeling and experimental validation. πŸ”₯πŸ’‘
pubs.acs.org/doi/10.1021/...

09.02.2026 09:48 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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Hyperpyramidalized alkenes with bond orders near 1.5 as synthetic building blocks - Nature Chemistry Alkenes are essential functional groups in organic chemistry, featuring well-defined geometries and bond orders of 2. In this study, cubene and 1,7-quadricyclene are calculated to possess unusual hype...

The Garg Lab just putting double bonds wherever now…
I mean c’mon we have RULES here!
Now everyone is gonna want olefins everywhere…

(Awesome paper out in @natchem.nature.com)
Really well done all - excellent work

21.01.2026 16:01 πŸ‘ 20 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1
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New reagents take the burn out of butyllithium Merck KGaA's non-pyrophoric butyllithium in poly(Ξ±-olefin) oil make BuLi stable to air and water

Dissolved in poly(alpha-olefin) oil, the reagents don’t ignite or smoke in air, making them easier to handle and less prone to degradation on storage, while maintaining performance across a range of reaction types.

20.01.2026 16:17 πŸ‘ 11 πŸ” 6 πŸ’¬ 0 πŸ“Œ 1
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Science isn’t the only universal language! πŸ•πŸ₯ŸπŸ₯¨
Thank you to all our group members who shared a taste of home at our International Christmas Dinner. πŸŒπŸŽ„
Amazing dishes, great conversations, and the best company!
#ChemistryLife #TeamSpirit #HolidaySeason

12.12.2025 11:13 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Check out the below video, where Giulia Iannelli presents her recently published work in Chemical Science!

"Diastereoselective Umpolung cyclisation of ketones promoted by hypervalent iodine"

You can read the full Chemical Science paper here: lnkd.in/et_eDKrX

Work authored by Nuno Maulide et al.

13.11.2025 13:45 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Photocatalytic oxygen-atom transmutation of oxetanes - Nature Nature - Photocatalytic oxygen-atom transmutation of oxetanes

www.nature.com/articles/s41...

16.10.2025 19:31 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Medicine Nobel prize recognises discovery of protective β€˜security guard’ regulatory T cells Research explained how body protects itself from the immune system, offering new ways to treat autoimmune disease

The Nobel prize in medicine or physiology has rewarded the unravelling of how our bodies protect themselves from our own immune system. This understanding has helped develop drugs to treat autoimmune disease and cancer.

06.10.2025 14:20 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Stirring Bars are Superstition?

Do you really need to stir your reactions? How do you know?

04.09.2025 19:39 πŸ‘ 58 πŸ” 11 πŸ’¬ 17 πŸ“Œ 9
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Gas Phase Separation of Modified Peptides for Activity-Based Protein Profiling Profiling the reactivity of the proteome with amino-acid level resolution requires the identification and quantification of reacted peptides in the presence of abundant unmodified peptides. Affinity-b...

Gas Phase Separation of Modified Peptides for Activity-Based Protein Profiling | Analytical Chemistry pubs.acs.org/doi/10.1021/...

22.07.2025 12:49 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Global Protein-Ligand Binding Affinity Profiling via Photocatalytic Labeling Protein-ligand binding, selectivity, and affinity dictate the effects of drugs and endogenous molecules in cells. Currently, potential protein-ligand interactions are identified by qualitative interpretation of proteomic, transcriptomic, or genomic data, then binding affinities of hits are measured using purified proteins or engineered reporter systems to validate and quantify the strength of individual interactions. Few methods enable simultaneous target identification and biophysical affinity measurement, and these either apply to specific enzyme classes or proteins with ligand dependent shifts in stability. Here we describe a general platform, termed Affinity Map, which leverages competitive binding analysis, high fidelity photocatalytic labeling, and high throughput proteomics for global quantitative binding affinity profiling. We show that this method is applicable to major classes of ligands, including small molecules, linear peptides, cyclic peptides, and proteins, and can measure affinities between unmodified ligands and proteins in cell lysates, organ extracts, and live cell surfaces. ### Competing Interest Statement J.B.G., N.Y., C.D.W., and S.P. are inventors on a provisional patent application (63/720,063) filed by Cornell University related to this work. National Institute of General Medical Sciences, https://ror.org/04q48ey07, R35GM147449, T32GM136640-TAN, R35GM147449-02S1
07.07.2025 16:12 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Mondo reale: andare avanti a lamentele, ma non si va al seggio!

08.06.2025 22:15 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Che conseguenze? Che c'Γ¨ un disinteresse generale?

08.06.2025 17:45 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

The house on Via Gemito by Domenico Starnone

07.05.2025 17:10 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Albert Einstein College of Medicine Launches Data Science Institute

Today, Einstein announced the launch of its new Data Science Institute. The dynamic, state-of-the-art resource will strengthen researchers’ ability to harness vast amounts of data for biomedical breakthroughs and innovations in scientific discovery and patient care. #datascience #research #MedSky

06.05.2025 19:12 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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BACCARA is hiring PhD students in battery research! πŸ”‹βš—οΈπŸ˜€

BACCARA = "International Graduate School of Battery Chemistry, Characterization, Analysis, Recycling and Application" @uni_muenster
Apply until June 1st.
www.uni-muenster.de/Baccara/inde...

06.05.2025 14:15 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Huge congratulations to Dr. Ranjini on successfully defending her PhD! πŸ₯³ Your research always kept us excited in all the right states. πŸ’‘ Wishing you all the best for your bright path ahead! πŸŒŸπŸ“ΈπŸ§ͺ #PhDoneΒ #Photochemistry

29.04.2025 17:48 πŸ‘ 13 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

There is definitely AT LEAST one defensive error here. Thus, by definition, not an inside-the-park homerun

28.04.2025 09:40 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Happy #InternationalLabDay! 🌍πŸ§ͺ
Celebrating experiments that fail, the occasional hit, and especially the teams that make it all possible. πŸ‘©πŸ»β€πŸ”¬πŸ‘πŸ»Let us know what your favorite piece of lab equipment is! βš— #Science #LabLife

23.04.2025 10:56 πŸ‘ 8 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Wordle 1,402 2/6

🟩⬜🟨🟨⬜
🟩🟩🟩🟩🟩

21.04.2025 23:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Bifunctional reagents and strain-release‍ cycloaddition – one reagent for the best of both worlds! πŸ«±πŸΌβ€πŸ«²πŸ½
Check out our latest publication on cyclic bifunctional reagents and in situ generated 2H-azirines in @jacs.acspublications.org:
pubs.acs.org/doi/10.1021/...
#OrganicChemistry #ChemTwitter

14.04.2025 12:13 πŸ‘ 17 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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13.04.2025 11:46 πŸ‘ 8 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1

International Booker prize

11.04.2025 20:39 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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From Structure to Function: Designing Iridium Catalysts with Spin-Forbidden Excitation for Low-Energy Light-Driven Reactions Herein we describe a comprehensive study of ligand effects on optoelectronic properties of a series of Ir(III) catalysts which undergo formally spin-forbidden excitation using low-energy light. We dem...

From Structure to Function: Designing Iridium Catalysts with Spin-Forbidden Excitation for Low-Energy Light-Driven Reactions | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/...

10.04.2025 19:09 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Interpreting Nature | Jed Perl β€œCΓ©zanne Drawing,” at the Museum of Modern Art, is a mindblower of a show. More than 250 works on paper, among them dozens of watercolors, reveal Paul

www.nybooks.com/articles/202...

10.04.2025 16:15 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

"An Ordinary Youth" by Walter Kempowski

10.04.2025 02:20 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Perfection is on the The International Booker shortlist! πŸ₯³

Congrats to Vincenzo Latronico, Sophie Hughes, and the other authors and translators. Many thanks to the wise judges. Vincenzo has events on Thurs & Fri in NYC. They will now be celebrations as much as literary talks.

08.04.2025 14:09 πŸ‘ 21 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Phenothiazine sulfoxides aren't just oxidation productsβ€”they're photocatalysts! 🌟Together with the @WengerOliver group, we investigated how they activate malonyl peroxides to synthesize Ξ³-lactones from simple olefins.

Check it out in @J_A_C_S πŸ‘‰

04.04.2025 12:37 πŸ‘ 10 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

His translation of Sand is one of my favorite books of the year so far. RIP

02.04.2025 02:35 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Lugansky - Scriabin Γ‰tude Op. 8, No. 12. Patetico
Lugansky - Scriabin Γ‰tude Op. 8, No. 12. Patetico YouTube video by Enchanted Wanderer

youtube.com/watch?v=SaIM...

02.04.2025 00:48 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0