Flyer for symposium: https://ctrlepiedit.sciencesconf.org/
Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org
More than 60% of Australian medical researchers left active research roles between 2019 & 2024 because they could not make ends meet - while my costings from the PBO suggest the govt could more than double annual spending from the MRFF without any effect on its base level of funding.
1/ 𧡠In our new paper, we show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2. www.cell.com/molecular-ce...
π¨ New paper from our lab just published in Natureπ¨
www.nature.com/articles/s41...
Discover how π± tumour formation is shaped by tissue context from the very beginning. Cancer is not driven by genetics alone
β¨Fantastic team led by Greta Skrupskelyte, Eduardo Rojo, @hariajith.bsky.social
Try spinning down your antibodies before using. You can also add some tween to your wash buffers
Frustrated I canβt be in person at #KSEpigenetics26. Unfortunately I couldnβt travel to Geneva from Australia due to the conflict in the Middle East.
Hoping everyone has a great conference and Iβll be able to join in person next time!
Losing sleep over #iPSC transgene silencing after differentiation?
Same here.
Bright in iPSCs.
Gone after differentiation.
Our paper in @cp-cellstemcell.bsky.social maps what actually keeps expression onπ
www.cell.com/cell-stem-ce...
π Free access (50 days):
www.sciencedirect.com/science/auth...
2026 Winner of the Lorne Genome Julian Wells Medal: Christine Wells (no relation!) @stemcellsystems.bsky.social congratulations, well deserved!!
Tongtong Wang presenting at Lorne Genome 2026
Tongtong Wang @petermaccc.bsky.social kicking off the computational Biology parallel session introducing EmbryoRadar, a machine learning model to identify developmental programs reactivated in cancer.
So exciting to see ASSCR partner with @isscr.org to support Australasian student and ECR researchers to attend the ISSCR Annual meeting in Montreal!! This Joint Travel Award, the first of its kind, will enable more interactions with the international community for our EMCR members!!
#stemcells
New ISSCR-ASSCR joint travel awards to support Australian students and EMCRs to attend @isscr.org annual meeting in Montreal
Our new preprint on SMCHD1! Weβve shown SMCHD1βs ATPase activity is critical for function in vivo, and excitingly a new DNA binding domain neighbouring the ATPase domain activates the enzymatic function, which is important for normal chromatin binding.
urldefense.com/v3/__https:/...
Lovely lab hike in Werribee Gorge to celebrate the EckMasLabβs 5th birthday π
New Spotlight in @aacrjournals.bsky.social
#Oncogene Γ #Ontogeny Γ #Plasticity shape leukemia biology & therapy response.
Two complementary studies show: mutations alone donβt explain disease behaviorβdevelopmental state and cellular plasticity matter.
aacrjournals.org/bloodcancerd...
π©Έπ§¬
EpiSci
Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
SS18::SSX activates Polycomb target genes without BAF β
Instead, transcription relies on EP300 via the SS18 QPGY domain
www.biorxiv.org/content/10.6...
β‘οΈ Coactivator targeting emerges as a new therapeutic strategy in synovial sarcoma π―
Team work from @banitolab.bsky.social and @uoe-igc.bsky.social
Synovial sarcoma is driven almost exclusively by a single oncofusion β SS18-SSX
For years, the assumptions on disease mechanisms were simple:
β‘οΈ SS18-SSX works by hijacking SWI/SNF chromatin remodeling activity
Our new study shows that assumption was wrong π§΅π
www.biorxiv.org/content/10.6...
#FragileNuclesome is back tomorrow! Join us to hear about exciting talks from:
- @au-ho-yu.bsky.social in @robklose.bsky.social's group about transcriptional control by SET1/MLL complexes
- @gcloner.bsky.social at @epicypher.bsky.social about the histone PTM landscape of the immune system
Great to catch up with alumni @nchoy.bsky.social who stopped by to visit the lab. So great to hear about your internship adventures with @robertife.bsky.social and see you doing so well!
Right now, the Government is starving medical research of full funding, even as it claims that science and research are national priorities. If our leaders truly value science as much as they say, then they must back their words with actionβand fund it properly.
Join the campaign!
Weβre delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells.
www.nature.com/articles/s41...
Humbled to have recieved NHMRC funding to understand molecular underpinnings of breast cancer plasticity.
Sadly, the bleak 8% success means many deserving applications went unfunded. Australia is missing out on scientific discoveries and all the direct and indirect benefits this brings our society.
π ASSCR Call for Reviewers (2026)
PhD-qualified members are invited to join the Abstract & Awards reviewer panel.
ποΈ Commitment AugβNov | ~20β30 abstracts
π
Apply by 12 Jan 2026
π docs.google.com/forms/d/e/1F...
#ASSCR #StemCells
The government canβt claim that medical research is a priority while failing to treat it as one. Nine in 10 leading researchers in Australia are missing out on government support for worldβclass proposals, leaving exceptional talent uncertain about their future.
Blog post: Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Celebrating a wonderful end to 2025! Wishing everyone a happy festive season and happy new year
Australiaβs medical and scientific research sectors save lives and are vital to our economy. The government has to step up and lean in to their potential.
Itβs small-minded and short-sighted to force them to wither on the vine, when we have money put aside for this purpose in the Future Fund.
The Medical Research Future Fund (MRFF) funds medical research in Australia. Only half the funds have been released. If you're an Australian and able to vote please use the form below to email your local MP to release the full amount of the MRFF
aamri.org.au/mrff/
Great first day of stem cell science on the beach at #ASSCR2025! Here is our @asscr.bsky.social president opening the conference. Highlights include keynote from @josh-brickman.bsky.social and presentation of @ausstemcell.bsky.social 2025 Metcalf awards. Congratulations to the worthy recipients!
Last chance! Early bird rates and oral presentation abstract submissions for Lorne Genome ππ§π ππ¨π―ππ¦πππ« πππ‘, ππππ - only one week away: https://www.lornegenome.org/registrations
We have a fantastic lineup of national and international speakers: https://www.lornegenome.org/speakers. Join us!
