Nichole Bouffard's Avatar

Nichole Bouffard

@nicholebouffard

postdocing @ WashU with Jeff Zacks and Zach Reagh | PhD @ UofT πŸ‡¨πŸ‡¦ | memory, hippocampus, and fmri autocorrelation | nicholebouffard.com πŸ³οΈβ€πŸŒˆ she/her

190
Followers
251
Following
10
Posts
18.11.2024
Joined
Posts Following

Latest posts by Nichole Bouffard @nicholebouffard

ConfPlan β€” CNS 2026 Vancouver

Heading to @cogneuronews.bsky.social ? I vibe-coded this tool to help you find relevant talks/posters, build a schedule, and export it to your calendar. Enter your research interests and it does the matching.
No personal data is stored. #CNS2026

06.03.2026 18:24 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
OSF

1/ 🚨 New preprint

Key Moments Scaffold the Semantic Structure of Narratives

Using spoken recall and annotations from three naturalistic datasets with topic modeling, we ask: which parts of a narrative contribute most to its semantic structure and subsequently memory?

Preprint: osf.io/dcfvw

04.03.2026 21:25 πŸ‘ 21 πŸ” 9 πŸ’¬ 1 πŸ“Œ 2
APA PsycNet

Excited to share our paper (with @jzacks.bsky.social), now out in JEP:LMC!

Event boundaries sometimes disrupt temporal order memory in list-based paradigmsβ€”but what happens in narratives with more complex structures that better resemble real life?

✨ Link: psycnet.apa.org/record/2027-...

03.03.2026 17:18 πŸ‘ 39 πŸ” 12 πŸ’¬ 2 πŸ“Œ 0
Preview
Adaptive episodic memory: how multiple memory representations drive behavior in humans and nonhumans | Physiological Reviews | American Physiological Society Episodic memory is a declarative long-term memory of a specific past experience. As such, it is multifaceted, encompassing both the objective and subjective components of that experience. These components can be flexibly represented at different levels of granularity, from precise, context-specific details to generalized, gistlike representations. In this review, we suggest that 1) multiple representations of an episodic memory at different levels of granularity are simultaneously encoded into a memory trace and 2) the relative weighting of these representations determines the extent to which a memory is reconstructed or reproduced at retrieval. We propose that this representational flexibility drives adaptive behavior by prioritizing reconstruction or reproduction depending on the age of the memory, its relationship to prior knowledge, current attentional goals or task demands, and individual differences. Drawing on research in humans and nonhuman animals, we show a close correspondence between psychological and neural representations of a memory across encoding, consolidation, and retrieval. Specifically, we discuss how hippocampal activity in humans and engram formation and activation in rodents support the reproduction of detailed memory representations, whereas schema formation across species, mediated by the medial prefrontal cortex, facilitates reconstruction and generalization to guide behavior. Finally, we consider how species- and individual-level differences shape episodic memory representations. By integrating findings across species, we illustrate how the correspondence between neural and psychological representations enables multiple memory representations to balance stability and flexibility, ultimately driving adaptive behavior.

How do memories guide behaviour?

Multiple memory representations, from detailed to gist-like, let us flexibly reconstruct or reproduce past experiences to behave adaptively across species.

Now out in Physiological Reviews with Morris Moscovitch, Melanie Sekeres & @brianlevine.bsky.social!

12.02.2026 19:03 πŸ‘ 56 πŸ” 25 πŸ’¬ 1 πŸ“Œ 1
Home | NIH (T32) Graduate and Postdoctoral Training Grant Program in Aging | Washington University in St. Louis Welcome to the NIH Aging and Development Training Grant program. Job postings POSTDOCTORAL FELLOWSHIP IN AGING The Aging and Developm...

The Aging & Development training program at WashU has an opening for a postdoc!

psychaging.wustl.edu

11.02.2026 16:37 πŸ‘ 4 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
Preview
Stand With Minnesota Donation Directory Stand With Minnesota is a hub for supporting, learning, and taking action to support Minnesotans impacted by ICE and federal enforcement.

People outside of Minnesota, in
case you are wondering how to help the current situation, this website has many current opportunities to donate and support people who need help in Minnesota. Help pay rent, get groceries, and provide other support for people in hiding.
www.standwithminnesota.com

27.01.2026 20:10 πŸ‘ 85 πŸ” 87 πŸ’¬ 0 πŸ“Œ 0

As tens of thousands across America protest the violence that ICE sows with impunity, federal agents shot and killed another person in Minneapolis today.

ICE terrorizes our cities. ICE puts us all in danger. Abolish ICE.

24.01.2026 18:00 πŸ‘ 29186 πŸ” 8235 πŸ’¬ 306 πŸ“Œ 197
Post image

New paper in Imaging Neuroscience by Nichole R. Bouffard, Mary Pat McAndrews, et al:

Single voxel autocorrelation reflects hippocampal function in temporal lobe epilepsy

doi.org/10.1162/IMAG...

24.01.2026 06:49 πŸ‘ 9 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Preview
a woman stands in front of a crowd on a stage with a lot of lights ALT: a woman stands in front of a crowd on a stage with a lot of lights

❗New Paper❗Is children's attention more like a spotlight that darts across time, or one that diffuses across many things at once? How might children's immature attention help their learning? Our Dev Sci Paper has answers! 🧡🎯

pubmed.ncbi.nlm.nih.gov/41549519/

23.01.2026 20:53 πŸ‘ 15 πŸ” 8 πŸ’¬ 2 πŸ“Œ 0

My lab is recruiting a postdoc and a full-time research technician to work on an NIH-funded project studying age-related changes in memory for naturalistic events. Behavior, fMRI, and blood-based biomarkers. 3+ years funding guaranteed.

Postdoc: tinyurl.com/ykjfbnj8

Tech: tinyurl.com/2f2hw3f5

15.01.2026 16:22 πŸ‘ 47 πŸ” 38 πŸ’¬ 2 πŸ“Œ 1
How We Learn Lab

🧠 Hiring a Research Assistant/Lab Manager! Share widely! πŸ“ St. Louis | ⏰ Full-time

We're launching the How We Learn Lab @WashU, studying attention, learning & memory interactions. Perfect for anyone interested in dev cog neuro who wants hands-on experience before grad school.

deckerlab.com

12.01.2026 15:23 πŸ‘ 30 πŸ” 23 πŸ’¬ 3 πŸ“Œ 2
Preview
Top U.S. Universities Are Quietly Removing LGBTQ+ Discrimination Protections From the Ivy League to elite state schools, this list might surprise you

NEW: My research has found that 17 of the 200 highest-ranked U.S. colleges have removed references to gender identity, gender expression, and/or sexual orientation from their nondiscrimination policies. See the full list here: medium.com/prismnpen/to...

07.01.2026 16:25 πŸ‘ 39 πŸ” 37 πŸ’¬ 1 πŸ“Œ 5
Post image

(1/5)
🧡Our new preprint shows how the brain develops to transform how kids, teens & adults represent & navigate their world: shifting from local, moment-to-moment memories in childhood to integrated, global cognitive maps in adulthood 🧠

Paper: www.biorxiv.org/content/10.6...

16.12.2025 16:32 πŸ‘ 21 πŸ” 11 πŸ’¬ 1 πŸ“Œ 1

Congrats Prof Hong!!! They are lucky to have you!

02.12.2025 14:28 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Hippocampal Drift Rate Reflects the Temporal Organization of Memories When freely recalling past events, individuals tend to successively remember stimuli that were studied close together in timeβ€”a phenomenon known as temporal clustering. Temporal clustering is thought ...

How do changes in context influence how we organize our memories in time?

Faster contextual changes are associated with faster drift in hippocampal activity and reduced temporal clustering in recalled memories.

Elegant work led by @lindsayrait.bsky.social!

www.jneurosci.org/content/45/4...

20.11.2025 14:37 πŸ‘ 54 πŸ” 17 πŸ’¬ 2 πŸ“Œ 0
OSF

Super excited to share my first preprintΒ with Katherine Duncan and Morgan Barense (@barense.bsky.social) -- "Memory strength at reactivation, not memory age, governs prediction error driven updating of naturalistic event memory"! πŸ§ πŸŽ‰https://osf.io/preprints/psyarxiv/q9rkn_v1

18.11.2025 22:08 πŸ‘ 47 πŸ” 13 πŸ’¬ 0 πŸ“Œ 3
APA PsycNet

I’m also on the job market! If you’re working on predictive processing, event cognition, or computational modeling β€” or know of exciting postdoc opportunities β€”please DM!
πŸ“„ Paper: psycnet.apa.org/record/2026-...
πŸ™ With: Matt Bezdek, Tan Nguyen, Chris Hall and @jzacks.bsky.social

12.11.2025 21:31 πŸ‘ 1 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Excited to share that our new paper, β€œPredictive Looking and Predictive Looking Errors in Everyday Activities,” is now out in JEP: General! 🧠
We examined how people’s eye movements reveal both their predictions and their prediction errors while they watch everyday actions.
πŸ‘‡

12.11.2025 21:31 πŸ‘ 7 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
DeckerLab

Excited to share that I'm joining WashU in January as an Assistant Prof in Psych & Brain Sciences! 🧠✨!

I'm also recruiting grad students to start next September - come hang out with us! Details about our lab here: www.deckerlab.com

Reposts are very welcome! πŸ™Œ Please help spread the word!

01.10.2025 18:30 πŸ‘ 77 πŸ” 33 πŸ’¬ 6 πŸ“Œ 1
Preview
Temporal dedifferentiation of neural states with age during naturalistic viewing - Communications Biology Movie fMRI data reveals age-related lengthening of neural states in visual and prefrontal regions, reflecting reduced temporal differentiation while preserved alignment with perceived events suggests stable coarse event segmentation.

The brain represents the world around us as a series of neural states - stable patterns of activity that change as we move from one event to the next.

New paper by @selmalugtmeijer.bsky.social showing that neural states get longer as people age. #PsychSciSky

nature.com/articles/s42003-025-08792-4

30.09.2025 16:03 πŸ‘ 65 πŸ” 25 πŸ’¬ 5 πŸ“Œ 4
Preview
Sinclair Lab The Learning & Behavior Change Lab at Rice University, directed by Dr. Sinclair

🌟 Excited to share that I'm recruiting PhD students in Psychology for my new lab at Rice University this cycle (Signal boost appreciated!)

To learn more, check out the Learning & Behavior Change Lab website:
www.sinclairlab-rice.com

Applications are due Dec 1st: psychology.rice.edu/graduate/pro...

08.09.2025 15:45 πŸ‘ 63 πŸ” 48 πŸ’¬ 2 πŸ“Œ 1
On the left: an illustration from Brooke's 1904 rendition of Goldilocks and the Three Bears, where Little bear discovers their favourite chair is broken 😲. On the right, a sketch of what a corresponding "situation model" might contain.

On the left: an illustration from Brooke's 1904 rendition of Goldilocks and the Three Bears, where Little bear discovers their favourite chair is broken 😲. On the right, a sketch of what a corresponding "situation model" might contain.

How might stories shed light on brain function? Check out this opinion piece by @alexbarnett.bsky.social and I about the DMN and "situation models" -- our understanding of the current "state of affairs" in a story (or even experience).

www.sciencedirect.com/science/arti...

05.09.2025 13:33 πŸ‘ 52 πŸ” 20 πŸ’¬ 3 πŸ“Œ 0
Preview
A neural network with episodic memory learns causal relationships between narrative events Humans reflect on past memories to make sense of an ongoing event. Past work has shown that people retrieve causally related past events during comprehension, but the exact process by which this causa...

How does the brain🧠 make causal inferences and use memories to understand narratives🎬?

We built an RNNπŸ€– with key-value episodic memory that learns causal relationships between events and retrieves memories like humans do!

Preprint www.biorxiv.org/content/10.1...

w/ @qlu.bsky.social, Tan Nguyen &πŸ‘‡

05.09.2025 12:26 πŸ‘ 93 πŸ” 29 πŸ’¬ 3 πŸ“Œ 2

Next up, from @atabk.bsky.social and @wouterkool.bsky.social: Free recall is shaped by inference and scaffolded by event structure. In sum, Ata stuck hidden (and shifting) rules into a word list learning task, creating "events" that influenced the structure of recall.

www.nature.com/articles/s44...

03.09.2025 21:12 πŸ‘ 21 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

I'm a behind on shouting out new papers!

From Angelique Delarazan: Narrative Coherence Warps the Timeline of Recalled Naturalistic Events. In sum, when recalling stories, people systematically deviate from temporal organization to follow the narrative threads.

pmc.ncbi.nlm.nih.gov/articles/PMC...

03.09.2025 21:10 πŸ‘ 24 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

1/ 🚨 Preprint alert!
How does the brain make sense of continuous experience?
We find that continuous experiences can be compressed using a subset of key moments that dominate comprehension and recall.
πŸ‘‰ https://doi.org/10.1101/2025.08.30.673233

03.09.2025 01:39 πŸ‘ 34 πŸ” 10 πŸ’¬ 2 πŸ“Œ 2
Preview
Repeated Viewing of a Narrative Movie Changes Event Timescales in The Brain Many experiences occur repeatedly throughout our lives: we might watch the same movie more than once and listen to the same song on repeat. How does the brain modify its representations of events when...

How do the brain’s event representations change as we gain familiarity with an experience?

Brain regions’ representations can become coarser or finer as event familiarity increases. Fine-tuning predicts memory recall.

Excited to share this work with Narjes Al-Zahli & @chrisbaldassano.bsky.social!

02.09.2025 13:37 πŸ‘ 121 πŸ” 40 πŸ’¬ 1 πŸ“Œ 1
OSF

New preprint from Yining Ding @liliand.bsky.social! People use semantic event knowledge and grouping to remember the temporal order of events.
osf.io/preprints/ps...

25.08.2025 14:27 πŸ‘ 26 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0

Yes! I’m really looking forward to it too!

24.08.2025 23:19 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thank you Mariam ☺️

24.08.2025 22:08 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0