Adam Jozwiak

Enzymatic twists evolved stereo-divergent alkaloids in the Solanaceae family - Nature Communications Researchers uncover how plants control the stereochemistry of steroidal alkaloids, key compounds in defense. They show that evolution of GAME8 enzymes in Solanum species has shaped alkaloid diversity,...

Thrilled to share our new paper! We discovered that wild tomatoes in the Galápagos are re-evolving ancestral chemical defenses—literally flipping a molecular switch back in time. One enzyme, one atom, one evolutionary twist. @ucriverside.bsky.social @nature.com

www.nature.com/articles/s41...

A “GAME” changer in plant secondary metabolism | Plantae Cholesterol, an essential structural component of membranes and a precursor for steroid hormones, serves as a key metabolite at the interface of primary and secondary metabolism. However…

Plant Science Research Weekly -- A “GAME” changer in plant secondary metabolism (Science) @adamjozwiak.bsky.social (Summary by Ching Chan) https://plantae.org/a-game-changer-in-plant-secondary-metabolism/

#PlantaePSRW

A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids | Science Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heterologous hosts has remained a challenge. We discovered ...

A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids | Science

Growing safer spuds: Removing toxins from potatoes Scientists have discovered a way to remove toxic compounds from potatoes, making them safer to eat and easier to store.

Scientists have identified a method to reduce toxic compounds in potatoes, enhancing their safety and storage. This advancement could benefit sustainable agriculture and space farming. doi.org/g8wj3k

A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heter...

A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids | Science www.science.org/doi/10.1126/... @science.org

A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heter...

Our latest research, “A Cellulose Synthase-like Protein Governs the Biosynthesis of Solanum Alkaloids,” is now published in Science! Discover how plants use GAME15 to defend themselves and how this discovery could revolutionize agriculture. @science.org
www.science.org/doi/10.1126/...