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Brigid Flanagan

@bflanaga

Research Operations Consultant | Book lover | Nurse | Former New Englander now back home in Ireland ...Co.Monaghan | News Hound | #clinicalresearch

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16.11.2024
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Latest posts by Brigid Flanagan @bflanaga

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Gum Disease and Dementia Risk in 2026: A Caregiver's Guide The link between gum disease and dementia risk. Learn why oral health is a modifiable risk factor and get practical tips for dental care.

Gum Disease and Dementia Risk: Why Oral Health is Critical for Seniors dailycaring.com/gum-disease-...

#Alzheimers #dementia #caregiving #health #wellness

06.03.2026 21:08 πŸ‘ 25 πŸ” 14 πŸ’¬ 1 πŸ“Œ 1
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Best evidence yet that GLP-1 drugs reduce the risk of substance abuse, from >600,000 US Veterans with T2 diabetes across alcohol, nicotine, opioid, cocaine, cannabis @zalaly.bsky.social
@bmj.com
www.bmj.com/content/392/...

05.03.2026 00:18 πŸ‘ 201 πŸ” 50 πŸ’¬ 2 πŸ“Œ 3

WELL NOW, would you look at that?

A massive, 26-YEAR-LONG study of MORE THAN 2.4 MILLION people in Sweden found found NO EVIDENCE to support a causal link between acetaminophen (the API in Tylenol) use during pregnancy and increased risk of autism, ADHD, OR intellectual disability in children.

01.03.2026 17:00 πŸ‘ 3629 πŸ” 1050 πŸ’¬ 38 πŸ“Œ 25
The risk of kidney disease increases following SARS-CoV-2 infection compared to influenza - Communications Medicine Zhang et al. utilized a large real-world dataset from more than three million adults in the United States to compare the incident of kidney disease risks following COVID-19 and influenza infections. T...

The risk of kidney disease increases following SARS-CoV-2 infection compared to influenza πŸ”“
www.nature.com/articles/s43...

25.02.2026 22:13 πŸ‘ 7 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

A lot of people, including me, were wondering how an IRB could ever approve this study.

The answer is that no IRB did. The person who β€œsigned off” on approval from the only ethics board that reviewed it had resigned three years earlier. His signature was used without his knowledge.

21.02.2026 02:43 πŸ‘ 4282 πŸ” 2087 πŸ’¬ 86 πŸ“Œ 98

This is beside the point -- a very important point -- but that photo show one of the most beautiful urban landscapes I've seen in a long time. A busy city, full of walkers, bikers, and street cars, and no private automobiles in sight. (Or, if there are any, they're damn hard to find.)

13.02.2026 18:36 πŸ‘ 74 πŸ” 10 πŸ’¬ 3 πŸ“Œ 0
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Inclusion of Retracted Studies in Systematic Reviews and Meta-Analyses of Interventions This systematic review and meta-analysis identifies reports of systematic reviews that included retracted studies in their meta-analyses, and assesses the impact of these retracted studies on the resu...

A pleasingly meta-meta-analysis with a very displeasing outcome: jamanetwork.com/journals/jam...

13.02.2026 02:58 πŸ‘ 15 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

"Medtronic LINQ implantable cardiac monitors are AI-assisted devices that are alleged to have failed to recognize abnormal rhythms or pauses in patients. Again, no incidents of patient harm are known.

12.02.2026 08:10 πŸ‘ 1 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
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Rare, dangerous side effects of some COVID-19 vaccines explained β€œGroundbreaking” study uncovers why adenovirus-based shots caused life-threatening blood clots and bleeding in some people

Five years after the rollout of Covid-19 vaccines started, it seems the mystery of why the Astra-Zeneca and J&J vaccines led to a rare but deadly side effect of unusual blood clots and bleeding has finally been solved. 

It's a fascinating case of molecular mimicry that may help make vaccine safer.πŸ§ͺ

11.02.2026 22:10 πŸ‘ 620 πŸ” 246 πŸ’¬ 12 πŸ“Œ 23
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Prenatal paracetamol exposure and child neurodevelopment: a systematic review and meta-analysis Current evidence does not indicate a clinically important increase in the likelihood of autism spectrum disorder, ADHD, or intellectual disability in children of pregnant individuals who use paracetam...

Not that most rational people would need to hear this--it is reassuring to know that scientists take the time to evaluate & show that #Acetaminophen aka #Tyelenol aka #Paracetemol when used in #pregnancy DOES NOT have any associations with #Austism spectrum πŸ§ͺ🧠 www.thelancet.com/journals/lan...

17.01.2026 17:35 πŸ‘ 16 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0

Some good news for a change.

15.01.2026 23:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Very exciting news for families affected by Huntington's disease. A light in the darkness...

04.01.2026 21:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Even Low Doses of Aspartame Could Have Alarming Health Effects, Study Finds The artificial sweetener aspartame can be found in everything from chewing gum to fizzy drinks and tabletop sweeteners.

The artificial sweetener aspartame can be found in everything from chewing gum to tabletop sweeteners. A new study of mice suggests that even at low doses, the sugar substitute may have negative impacts on heart and brain health over the long term.
www.sciencealert.com/even-low-dos...

30.12.2025 04:06 πŸ‘ 68 πŸ” 32 πŸ’¬ 7 πŸ“Œ 5

12 former @fda.gov commissioners from both parties just went on the record in @nejm.org calling Vinay Prasad’s vaccine framework a threat to public health. They bring more than 3 decades of leadership at the agency, and it is hard to think of a more forceful warning. 🧡

www.nejm.org/doi/full/10....

04.12.2025 00:07 πŸ‘ 122 πŸ” 61 πŸ’¬ 2 πŸ“Œ 2

Fabulous news!

28.11.2025 20:47 πŸ‘ 10 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

Great news for people with asthma!

27.11.2025 10:30 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Experimental mRNA flu vaccine shows superior efficacy against symptomatic illness

Two exciting phase two trials show incredible success of mrna vaccines for seasonal flu with infectious symptoms prevented in some healthy individuals. πŸ§ͺ🧡

26.11.2025 06:42 πŸ‘ 245 πŸ” 70 πŸ’¬ 3 πŸ“Œ 2
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Federal cuts upended clinical trials. A new study reveals the toll. Grants for 383 clinical trials were terminated and the funding disruptions affected more than 74,000 trial participants, according to new research.

A new study found the Trump administration’s cuts to NIH grants disrupted more than 380 clinical trials, affecting over 74,000 participants.

The cuts disproportionately impacted trials on infectious diseases and minority communities.

17.11.2025 23:00 πŸ‘ 127 πŸ” 97 πŸ’¬ 9 πŸ“Œ 17
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The New Politics of New Drug Approval | Milbank Memorial Fund As feared at the start of the second Trump Administration, the Food and Drug Administration (FDA) has proven a willing good soldier in fulfilling the

From Paul Kim on leucovorin: "Proffering a proactive guarantee of approval on the basis of a limited, non-trial-based dossier effectively broadcasts that the FDA is prepared to approve new drugs without clinical trials."

www.milbank.org/quarterly/op...

11.11.2025 10:53 πŸ‘ 7 πŸ” 6 πŸ’¬ 1 πŸ“Œ 1

Some good news for a change.

03.11.2025 23:15 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Effectiveness of Colchicine for the Treatment of Long COVID This randomized clinical trial evaluates the superiority of colchicine over placebo among adults with long COVID in improving functional outcome at 52 weeks from baseline.

Effectiveness of Colchicine for the Treatment of Long COVID: A Randomized Clinical Trial

jamanetwork.com/journals/jam...

"among adults with long COVID, colchicine did not improve functional capacity, respiratory function, or inflammatory markers."

#LongCovid #PASC

26.10.2025 14:33 πŸ‘ 24 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0

100% agree. It is difficult to challenge misinformation when you cannot access the data to support your argument.

29.09.2025 21:14 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Pregnant Women Should Not Use Cannabis, New Medical Guidelines Say Marijuana during pregnancy is linked to poor birth outcomes and developmental delays in children, a leading medical society advised.

πŸ§ͺ New ACOG guidelines warn against cannabis use in pregnancy. Despite its use for nausea, mounting evidence links it to preterm birth, low birth weight, and neurocognitive delays in children. THC is known to cross the placenta and concentrate in the fetal brain.
#MedSky

23.09.2025 03:51 πŸ‘ 38 πŸ” 19 πŸ’¬ 4 πŸ“Œ 0

Correlation is not causation. Read the cited papers!

23.09.2025 06:47 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Hardly a surprise!

23.09.2025 06:44 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Wow! A drug that is off patent and readily available. Excellent news!

11.09.2025 07:56 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Air Pollution Linked to Toxic Protein Clumps Driving Lewy Body Dementia - Neuroscience News A new study reveals a molecular link between fine particulate air pollution (PM2.5) and Lewy body dementia, a devastating neurodegenerative condition.

#ResistanceEarth
#BlueEarth

Researchers have linked fine particulate air pollution (PM2.5) to the buildup of alpha-synuclein protein clumps called Lewy bodies. The clumps leads to neurodegenerative diseases, including Lewy body dementia and Parkinson's disease.

neurosciencenews.com/air-pollutio...

07.09.2025 22:24 πŸ‘ 161 πŸ” 97 πŸ’¬ 16 πŸ“Œ 5

Hopefully the grant money is locked in and can't be rescinded!

29.08.2025 17:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0