Group picture including Steven "Epstein? I barely knew him" Pinker. www.thenerve.news/p/epstein-bi...
06.03.2026 13:22
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Group picture including Steven "Epstein? I barely knew him" Pinker. www.thenerve.news/p/epstein-bi...
New @nature.com
The brains of Super Agers produce more neurons than people some 50 years younger, a neurogenesis resilient signature linked to exceptional cognitive health and memory skills
nature.com/articles/s41...
"The only thing worse than being talked about is not being talked about.”
Save the date 👆🧵 Neuroimaging Statistics Workshop, 12-13 June, @ohbmofficial.bsky.social 2026 satellite meeting, w/ @ohbmossig.bsky.social's BrainHack. Keith Worsley lecture by Sir. John Aston, + great work at Neuro/Stats/ML/AI interface. Registration opens soon! sites.google.com/view/nsw2026
Italy
Left: Pathways involved in brain energy metabolism. Energy metabolism refers to processes involved in energy production from nutrient molecules. Glucose is the main energy source in the brain under normal physiological conditions. Glucose entering brain cells can be utilized in three parallel pathways. It can be processed through glycolysis to produce 2 ATP and 2 pyruvate molecules (blue). Lactate dehydrogenases catalyze the interconversion of lactate and pyruvate (purple). Pyruvate is transported into mitochondria, where it enters the TCA cycle to generate high-energy electron carriers NADH and FADH2 (green), driving the complete oxidation of glucose through the mitochondrial electron transport chain (red). Glucose entering the brain can also enter the PPP. PPP is an anabolic pathway that uses glucose to produce 5-carbon sugars and NADPH, an essential co-factor used in nucleotide and lipid biosynthesis (yellow). Glucose can also be stored in the form of glycogen via glycogen synthase, a process mainly active in astrocytes. Right: Energy pathway maps. Colors show z-scored mean expression values across all genes in each pathway. ppp, pentose phosphate pathway; tca, tricarboxylic acid cycle; oxphos, oxidative phosphorylation; lactate, lactate metabolism and transport.
How are energy #metabolism pathways distributed across the #cortex? @alaindagher.bsky.social &co map five pathways in the human #brain, linking metabolic organization with brain structural & functional properties, as well as developmental dynamics @plosbiology.org 🧪 plos.io/4c1JVp8
Nature's Impact Factor is in the Epstein Files. Really.
"[S]ociological graduate students are required routinely to hand in [...] new discoveries equalling Gregor Mendel's" 😭
I think in sociology this has stopped, but psych is unfortunately still going strong bsky.app/profile/cele...
The Shingles vaccine has outperformed all expectations. Why?
erictopol.substack.com/p/spotlight-...
Our lab, located at the University of Alberta (Canada), is hiring a postdoctoral scholar and/or PhD student to work on the contribution of genetic mutations to neurological disorder mechanisms and response to treatments. Please share widely! can-acn.org/postdoctoral...
Everyone: academic publishing is broken.
Also everyone ( on a search committee): candidate has a cell paper and a nature neuroscience paper.
Whom the gods wish to destroy they first call promising?
If you're (1) into nhp neurophysiology and/or biological motor control, (2) a foreign big shot and (3) interested in moving here, please reach out -- this new program looks extremely attractive (min. $8M over 8y)! www.uwo.ca/research/can...
Most published personality profiles are super similar! @kerliilv.bsky.social clustered 162 NEO PI personality-phenotype profiles. 70% of profiles belong to just 3 clusters , and 89% belong to just 5 😱!
Check out the thread for more! 👇
@alaindagher.bsky.social @renemottus.bsky.social
Brain size links neurodevelopment to neurodegeneration in Parkinson's disease https://www.medrxiv.org/content/10.64898/2025.12.09.25341901v1
As an editor for many years, I still believe in the importance of peer review, especially in journals closely linked to specific scientific communities/societies. It's not a guarantee of course.
It's like if you weed your garden regularly. Will you still have weeds? Yes. Does it help? Also yes.
Cortical expansion and genetic risk for PD.
Led by Houman Azizi and Nooshin Abbasi.
With @ptenigma.bsky.social @misicbata.bsky.social @yasharneuro.bsky.social @ndrewvo.bsky.social and many others www.medrxiv.org/content/10.6...
Yes. The ones that were rejected😀
Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism: Neuron www.cell.com/neuron/fullt...
lol. No one who has done time in Canadian Academia has any illusion that it’s a meritocracy.
I asked nano banana in Gemini 3.0 to make a diagram explaining two-sample MR with an arrow indicating pleiotropy. This is what it came up with. Not great - and what on earth is "pleizorotty"?
Why does your brain shrink in Parkinson’s? Word shrink in this case refers to measurable loss of brain tissue (atrophy), which reflects thinning of cortex/loss of volume in key brain regions. New paper shows widespread atrophy following brain’s wiring diagram and local biological vulnerabilities.
Jonny Smallwood @themindwanders.bsky.social was a beloved friend and mentor. He was taken from us too soon. His was a beautiful mind who understood the beauty of minds. As ever before, his kind voice guides me and his work will continue. We miss you Jonny. www.cbs.mpg.de/news/obituar...
New paper with @statsepi.bsky.social and @deevybee.bsky.social in which we show there's really no evidence for a link between the gut microbiome and autism www.cell.com/neuron/fullt...
New paper in Imaging Neuroscience by Ying-Qiu Zheng, Saad Jbabdi, et al:
An image quality transfer approach for localising deep brain stimulation targets
doi.org/10.1162/IMAG...
Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧵
