Meanwhile, Spain's massive investment in renewables is paying dividends now: with prices for Spanish industry and consumers low and stable compared with other European economies.
www.ft.com/content/ac77...
With Eugene Koonin, we propose a concept of “the selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268
Final version @nature.com of our paper describing unconventional multicellular development in a choanoflagellate inhabiting an extreme environment. A ton of new data since the first @biorxivpreprint.bsky.social preprint (which we've kept updating).
A brief 🧵 (carried over from the old place)
Can't miss this amazing study on the ribosome structure of the Haloferax archaeon 👏🏼👏🏼👏🏼!! Congrats to my good friend @diorgeps.bsky.social and all the other ppl involved!!
Congratulations!! 👏🏼👏🏼👏🏼
Great job!! 👏🏼👏🏼👏🏼
Congratulations to all authors!
Hello epithelial mechanics fans!! I’m Juanma @juanmagararc.bsky.social 👋 I work on cell mechanics (see celldynamicslab.com) and use Flipper-TR FLIM to probe membrane biophysics in cells.
Join me on this tour about Flipper: what it measures, strengths, advice, cool case studies, and cute drawings!
Espadas, J., Souza, D. P., Hakala, M., García-Arcos, J. M., Tran, J., Kumar, A., Marcuello, C., Merino, A., ..., Toret, C. P., & Roux, A. (2025). Molecular basis for cellular compartmentalization by an ancient membrane fission mechanism. bioRxiv. #EpithelialMechanics
buff.ly/OQv9qMw
finishing with a path to multicellularity via ultrastructure complexity #cellbiologyofeukaryogenesis @sbcf.bsky.social
a big thank you to all speakers!
from viruses to lipid transfer and multiple symbiosis in early eukaryotes...
#cellbiologyofeukaryogenesis @sbcf.bsky.social
next step about ins and outs of symbiosis in eukaryogenesis
#cellbiologyofeukaryogenesis @sbcf.bsky.social
fantastic start for our Eukaryogenesis meeting with a vivid overview of membrane remodelling systems in Archae!
Today at 17:00 CET - the first #MembraneTrafficking seminar of 2026.
Giovanni D’Angelo (EPFL) and Sean Munro (MRC-LMB), explore protein trafficking, retention, and sorting at the Golgi.
Join us for exciting discussions about the best organelle!
Details at felixcampelo.wixsite.com/membranetraf...
Join us this Thursday (Jan 29) at 5pm CET for the first #MembraneTrafficking seminars of 2026, featuring two outstanding scientists, Giovanni D'Angelo (EPFL) and Sean Munro (@cellbiol-mrclmb.bsky.social), and the shared topic of protein trafficking, retention & sorting at the #Golgi 🥞
A reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!
🚨 Want to know how we demonstrated the importance of sterol-rich membrane microdomains for M. marinum infection?
Check out our latest paper published in Science Advances 👇
www.science.org/doi/10.1126/...
✨ Big thanks to everyone, especially Cristina Boehm-Bosmani, @soldatilab.bsky.social ! ✨
1. As we recently joined BlueSky, we want to repost this story for all newcomers!
We sat down with @radler92.bsky.social to get more insight into the unique videos from his recent preprint on Promethearchaeota (formerly Asgard archaea).
doi.org/10.1101/2025...
(Videos and info below)
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK.
Please repost!
Congrats Omaya!! 👏🏼👏🏼👏🏼👏🏼
An Asgard Archaeon (Lokiarchaeum ossiferum) growing and retracting its arms
And ‘Searching for the Asgards’ the movie: www.youtube.com/watch?v=mgmE...
An 8-nm precise map in live cells, which revealed #actin aster formation by #myosin V-driven transport of #formin.
Happy to see this work now out! 😃
In collaboration with @kaksonen.bsky.social lab
#yeast #pombe #cell_fusion
@biology-unige.bsky.social
📢Internships on cellular nematics!
🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.
📧Feel free to DM or email me with any questions.
Absolutely! And Asgard archaea don’t just have ESCRT-III, they also encode ESCRT-I, ESCRT-II, and ubiquitin, maybe an ancient endomembrane trafficking system? And with the internal vesicles described by the Baum and Bharat groups… it really feels like exciting discoveries are coming!!🤩
Happy to share a new preprint from the lab: Marko became interested in whether the disordered linker of FtsZ might influence how the protein organizes into the Z-ring. And this led to some surprising findings!
Preprint: www.biorxiv.org/content/10.1...
@colomlab.bsky.social @labvanni.bsky.social @kaksonen.bsky.social @buzzbaum.bsky.social @Christopher Toret @rouxlab.bsky.social
Thank you all for the amazing work!!
All credits to the dreamteam that made this possible! what a pleasure and honor working with these people! 🥰
@diorgeps.bsky.social @mhakala.bsky.social @juanmagararc.bsky.social @joshuatran.bsky.social @mudgal17.bsky.social @Carlos Marcuello @Andrea Merino
The crucial test: We fused Heimdall Hofund to a fission-defective yeast ESCRT-III protein (Did2). This chimera restored Mup1 trafficking to vacuoles back to wt! A short amphipathic helix, present in Asgard and retained as fragments in eukaryotes, acts as a minimal membrane fission trigger!
Eukaryotic ESCRT-IIIA paralogs, known to form heteropolymers, retain Hofund elements at their N-termini.
In yeast, mutating these elements blocks ESCRT-III-dependent Mup1 transport to vacuoles.
So these elements matter in eukaryotes too.
Is this Asgard-specific, or conserved with their eukaryotic paralogs?
Hard to tell, since the exact molecular mechanism of fission by eukaryotic ESCRT-III remains blurry, probably due to its complexity.
Let’s figure it out!
