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Ayush Valecha

@ayushvalecha

Doctoral Researcher modeling protective symbiosis @mpi-evolbio.bsky.social‬ #evolutionary_theory | #epidemiology | #microbiology

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10.11.2023
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Latest posts by Ayush Valecha @ayushvalecha

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Deltaviruses spread through a viral Trojan Horse Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expr…

We found a viral Trojan Horse: a virus can hide inside another virus.This one surprised us: deltaviruses don’t just borrow a helper virus. They can travel inside it.
A literal Trojan Horse “virus-in-a-virus” route into cells. 🤯 Kudos to 1st author @viroscope.bsky.social and co-authors !

06.03.2026 18:29 👍 153 🔁 75 💬 7 📌 8
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07.03.2026 02:47 👍 15 🔁 6 💬 1 📌 0
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I am looking for a PhD student to join my new Socio-Eco-Evo group, hosted in Katie Peichel's Evolutionary Ecology Division @ University of Bern. We're offering a fully funded 4-year position, studying social plasticity and behavioral adaptation among stickleback in Greenland. Please share around!

02.02.2026 12:01 👍 78 🔁 96 💬 1 📌 2
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A new preprint with Matthew Schmitt, @kiseokmicro.bsky.social and Vincenzo Vitelli makes a huge step forward in learning functional groups of components in complex biological systems. It's dimension reduction that speaks to biological function. www.biorxiv.org/content/10.6...

05.03.2026 12:22 👍 38 🔁 22 💬 0 📌 1
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Similar tumors can often respond very differently to immunotherapy. Why? A simple mathematical model reveals the possibility of two alternative evolutionary strategies, dictated by mutational loads www.sciencedirect.com/science/arti...

05.03.2026 12:21 👍 10 🔁 2 💬 0 📌 0
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New research from #BiologyLetters: Higher genetic variance of prey defense promotes fluctuation-dependent species coexistence royalsocietypublishing.org/rsbl/article... | #Ecology #Evolution

05.03.2026 12:00 👍 7 🔁 2 💬 0 📌 0

Go check out our new preprint about the loss of distyly in multiple Linum species 👇🌸 Many thanks to all co-authors!!

05.03.2026 09:25 👍 3 🔁 2 💬 0 📌 0
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Pyocyanin produced by Pseudomonas aeruginosa Creates Legacy Effects That Boost Antibiotic Resistance Evolution in Enterococci Polymicrobial infections are small communities of multiple interacting bacterial species. Interactions among constituent species may modify the growth of community members in the presence of antibioti...

New preprint:
www.biorxiv.org/content/10.6...

05.12.2025 14:27 👍 17 🔁 9 💬 1 📌 1

Is loss of distyly always associated with high selfing rates? And what are the genomic consequences? Read more about this in our new preprint on repeated loss of distyly in Linum, led by @zopos.bsky.social and @panazerv.bsky.social www.biorxiv.org/content/10.6...

05.03.2026 08:44 👍 7 🔁 5 💬 1 📌 1
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"Virulence is a context-dependent strategy, not a fixed trait"🦠🧫

📢Check out our latest Micro Briefing highlighting the exciting commentary from Dr Damien F. Meyer at Cirad & INRAE_France, published in Microbial Outlooks.

Read the full paper here🔗 https://doi.org/10.1099/mout.0.00001

05.03.2026 09:01 👍 5 🔁 2 💬 0 📌 1
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The final part of the story: "The arduous path to obligate asexuality in Daphnia" is out in #ProcB 🥳 royalsocietypublishing.org/rspb/article.... 1. Instead of comparing long-established asexuals to sexuals, we generated new asexual lineages to observe the transition in action.

04.03.2026 17:50 👍 19 🔁 16 💬 3 📌 0
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New post-doctoral research position in my phage-host interactions (Phi) laboratory in @otagomicroimmuno.bsky.social at @universityofotago.bsky.social New Zealand. The project is focused on defences against jumbo phages. Please share and if interested apply using the link in the comments.

04.03.2026 00:20 👍 49 🔁 47 💬 5 📌 1
Job Openings Explore exciting career opportunities at iDiv. Join a modern, international, and innovative research centre in the heart of Germany.

iDiv and @uni-jena.de are recruiting a Postdoctoral Researcher (f/m/d) in Trait-Based Community Ecology and Modelling.

Highlights:
🔺Full-time (100%, 40 h/week) with the option to reduce to 80%
🔺Fixed-term for 2 years
🔺Salary up to E13 TV‑L

📆 Apply by: 29 March 2026

www.idiv.de/career/job-o...

04.03.2026 08:29 👍 19 🔁 25 💬 0 📌 2
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Many organisms, including humans, reshape their environments in ways that influence the conditions faced by future generations. We ask whether this can favour biological variation with @irisprigent.bsky.social in our new paper. Thanks to @dee-unil.bsky.social @snsf.ch
www.pnas.org/doi/full/10....

03.03.2026 14:15 👍 25 🔁 17 💬 0 📌 1
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VACANCY - We’re searching for a Postdoctoral Researcher to join the newly appointed group of Dr @hassansalem.bsky.social, to explore the developmental biology of host-microbe symbiosis

www.jic.ac.uk/vacancies/po...

Deadline - 25 March 2026
Salary - £37,500 - £45,350
Contract - 3 years, full-time

03.03.2026 18:56 👍 22 🔁 25 💬 1 📌 4
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Simulations of your gut may predict which probiotics will stick A “digital gut” predicted which probiotics and high‑fiber diets would take hold in people's guts and produce healthier outcomes.

"Simulations of your gut may predict which probiotics will stick" www.sciencenews.org/article/prob...

Great reporting on our recent @plosbiology.org paper by @norabradford.bsky.social in Science News 📰

@isbscience.org

02.03.2026 18:41 👍 9 🔁 5 💬 0 📌 0
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With Eugene Koonin, we propose a concept of “the selfish ribosome”, under which evolution of life is viewed as a ribosomal takeover, where the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensures the propagation of the ribosome. arxiv.org/abs/2602.23268

03.03.2026 08:58 👍 222 🔁 95 💬 5 📌 13

We are offering a fully funded two-year postdoctoral position focused on sex chromosome evolution and speciation in the *Jaera albifrons* species complex. Please find the advertisement attached. We welcome applications from interested candidates. Join us :-)

03.03.2026 09:44 👍 16 🔁 16 💬 1 📌 0
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Unraveling posttranscriptional regulatory networks in phage infection Phages employ sophisticated transcriptional regulatory networks to optimize replication. Recently, Silverman et al. used RIL-seq (RNA interaction by l…

Like bacteria, phages use sRNAs to regulate gene expression! Out today in @cp-trendsmicrobiol.bsky.social, @mvelascogomariz.bsky.social and I highlight a recent RIL-seq study from the @saharmelamed.bsky.social lab that looked into posttranscriptional regulation of lambda!

tinyurl.com/lambda-RIL-seq

26.02.2026 13:29 👍 33 🔁 20 💬 1 📌 2

➡️ preprint from the lab! Bacteria have loads of antiviral defences in their mobile genetic elements (MGEs). So when MGEs move between bacteria, the defences move with them, generating a fast turnover of defences in bacteria. But what about the antiviral defence turnover in the MGEs themselves? 🤔

🧵👇

02.03.2026 08:36 👍 75 🔁 45 💬 1 📌 3
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A Nonparametric Approach to Practical Identifiability of Nonlinear Mixed Effects Models - Bulletin of Mathematical Biology Mathematical modelling is a widely used approach to understand and interpret clinical trial data. This modelling typically involves fitting mechanistic mathematical models to data from individual tria...

Well it turns out if you know something about the distributions of x and y, you *can* (sometimes) separately estimate their population means.

We explored some biological applications of this idea here:
doi.org/10.1007/s115...

02.03.2026 03:46 👍 12 🔁 3 💬 1 📌 0

New preprint out on bioRxiv!

www.biorxiv.org/content/10.6...

Can conjugative plasmids be used to control plasmid and pathogen spread?

Follow me down the rabbit hole that led to this story 🧵

26.02.2026 09:54 👍 48 🔁 31 💬 5 📌 1
2026 PhD – bourse d’excellence IVID – Graduate Plus

📢 Opportunity to apply for a PhD fellowship to join our group and work on MGE-MGE interactions and phage defence systems!
@mmsb-lyon.bsky.social

See informations about eligibility and research project on this web page: graduate-plus.fr/immunology-v...

Contact me if you are interested !

27.02.2026 15:45 👍 10 🔁 12 💬 0 📌 0
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#Emergence seminar, next session:

Evolutionary transitions in individuality: one concept, two criteria? - by Johannes Martens (CNRS,SND)

March 27, 11am (Brussels time)

On-line attendance possible (just pm me and I'll give you a link).

#philsci #philsky #philbio

27.02.2026 09:23 👍 15 🔁 5 💬 1 📌 2
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Our very own Rajalekshmi N. Sarma is on the line-up! 🎤 Women Science Show (Science Comes to Town) — Thu, 5 March 2026, 7.00 pm, STUDIO Filmtheater, Kiel. Six 10-minute talks from early-career women researchers. Free entry — bring friends & family 😊

27.02.2026 07:11 👍 4 🔁 2 💬 0 📌 0

Play isn’t only fun… it’s preparation for danger! Our new paper by @DharanishR in @royalsociety.org shows how protected juvenile environments boost #learning of risky behaviours via a protected early life period across some species. 🦂🦁 tinyurl.com/3w45xvz9 @cctb-wue.bsky.social @uni-wuerzburg.de

27.02.2026 09:19 👍 12 🔁 4 💬 0 📌 0
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The free-running property of circadian clocks is needed to tolerate changing photoperiods Schober et al. reveal a genetic pathway for converting the model circadian clock of S. elongatus from a free-running oscillator into a damped hourglass timer. The authors use a combination of modeling...

The free-running property of circadian clocks is needed to tolerate changing photoperiods

Synechococcus elongatus

@currentbiology.bsky.social from Michael Rust

www.cell.com/current-biol...

#Chronomicrobiology #ChronoSky

26.02.2026 08:19 👍 6 🔁 2 💬 0 📌 0
seminar announcement with photos of speakers and talk titles

seminar announcement with photos of speakers and talk titles

The integration of speciation seminar series is restarting, with the first session coming up on *Tuesday March 3rd @ 5pm CET*, featuring two talks by @naturalselection.bsky.social and @andreaestandia.bsky.social + career Q&A with @markravinet.bsky.social as part of the ECR in Speciation theme.

25.02.2026 16:29 👍 31 🔁 20 💬 1 📌 2
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Protease-Controlled Prophage Activation in Staphylococcus aureus: New Mechanisms Driving Antimicrobial Resistance and Virulence at University of St Andrews on FindAPhD.com PhD Project - Protease-Controlled Prophage Activation in Staphylococcus aureus: New Mechanisms Driving Antimicrobial Resistance and Virulence at University of St Andrews, listed on FindAPhD.com

📢 Funded PhD in molecular microbiology & phage biology

How do bacterial stress responses control prophage activation and horizontal gene transfer?

Join us at St Andrews to dissect Clp protease–mediated regulation in Staphylococcus aureus.

Apply:
www.findaphd.com/phds/project...

25.02.2026 14:39 👍 14 🔁 18 💬 1 📌 2
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Postdoc Ad Postdoctoral Position in Computational Phage Biology Microbial Genomics Group, Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Kraków PL Summary We are seeking a postdoctoral rese...

📢 Hiring a Postdoc in Computational Phage Biology (Kraków, Poland)

We study the evolution & structural modularity of prophage-encoded glycan-degrading enzymes in Klebsiella pneumoniae — combining genomics and AlphaFold-based analyses.

Details in attached PDF 👇

26.02.2026 08:44 👍 10 🔁 12 💬 1 📌 0