Hikaru Katani

Cell size matters: a unifying theory across the tree of life

Cell size matters: a unifying theory across the tree of life.
http://dlvr.it/TPgKwF

Marcin Czarnoleski (Jagiellonian University) & Wilco C.E.P. Verberk (Radboud University)
@cp-trendsecolevo.bsky.social
#CellBio2025

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis
http://dlvr.it/TPh6Bf

Yifan Cheng, Chuankai Zhou & colleagues
@cp-molcell.bsky.social
#CellBio2025

Great quantification with the well-integrated computational model to connect cellular behavior to tissue behavior of tissue spheroids.

Active foam dynamics of tissue spheroid fusion - Nature Communications Combining microscopy and modeling, the authors reveal that tissue fluidity, driven by active cell motion and interfacial tension, governs how living spheroids merge into larger structures.

Our paper is out in Nature Communications!

We combine two-photon microscopy and active foam modeling to show how cell-scale mechanics control the viscoelasticity and fusion of tissue spheroids, linking single-cell behavior to tissue-level properties.
🔗 www.nature.com/articles/s41...
#ActiveMatter

Cell wall patterning regulates plant stem cell dynamics The plant cell wall regulates development through spatiotemporal modulation of its chemical and mechanical properties. Pectin methylesterification is recognized as a rheological switch controlling wal...

Out in @science.org this week:
PME5 is sequestered in the nucleus and released during cytokinesis allowing its activity to be timed with cell division.

www.science.org/doi/10.1126/...

#PlantScience
#PlantSci

These immune cells won Nobel fame — can they solve autoimmune disease? Regulatory T cells, which help to dampen inflammation, are being used in clinical trials against ailments such as rheumatoid arthritis.

The class of immune cells at the centre of Monday’s Nobel prize is showing promise as a treatment for autoimmune diseases, cancer and even organ transplants — but there are still key challenges to overcome before these cells can be used in therapies in the clinic.

go.nature.com/4nGC5V9

A Nobel medal

BREAKING: The Nobel Prize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks”

Stay tuned for more.
#NobelPrize

Connecting chemical and protein sequence space to predict biocatalytic reactions - Nature A two-phase machine-learning-based tool making use of high-throughput experimentation is introduced to examine the connections between chemical and protein sequence space and predict productive biocatalytic reactions among substrate and enzyme pairs.

Really cool and powerful!

www.nature.com/articles/s41...

Songs of the striped mouse show who’s friend and who’s foe Ultrasonic calls, too high for the human ear to detect, convey a wealth of information across the rodent’s territory.

In the African desert, wild mice ‘sing’ tunes that don’t travel far but help the animals to tell neighbours from strangers

go.nature.com/3K0SGDZ

Screenshot of the article header from Synthese, titled ‘Driftability and niche construction,’ authored by Alejandro Fábregas-Tejeda and Grant Ramsey.

Organisms alter selective pressures in many ways. But can they also shape the drift probabilities of their populations? In our recent paper, we argue that they can—and, in doing so, we expand the scope of #nicheconstruction theory 📄👇 link.springer.com/article/10.1... #HPBio #evobio #ecology #HPS

Phagocytic clearance of targeted cells with a synthetic ligand - Nature Biomedical Engineering A synthetic protein ligand enables the recognition of surface proteins on unwanted cells, targeting them for engulfment and elimination in vivo.

Wonderful engineering research utilizing phospholipid dynamics on cell membranes with well-confirmed in vitro results.

www.nature.com/articles/s41...