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John Pearson

@jmxpearson

Computational neuroscience, neuroML, natural behavior. I charge more for miracles. PI @ pearsonlab.github.io. @dukemedschool.bsky.social.

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03.11.2024
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Latest posts by John Pearson @jmxpearson

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Linking neural manifolds to circuit structure in recurrent networks Neural population activity can be described either by low-dimensional dynamics on neural manifolds or by single-neuron selectivities. Using a theoretical approach, Pezon et al. relate these two statistical descriptions to circuit structure in recurrent networks. Their results reveal both degeneracies and specific constraints in how circuit structure shapes neural activity.
06.03.2026 16:23 ๐Ÿ‘ 36 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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"Evolution Evolving is a landmark book written by stellar scientists who have brought together numerous interesting and relevant examples that show why development matters for evolution."

Thankyou @kampourakisk.bsky.social for your wonderful review in American Biology Teacher. See shorturl.at/2Gso8

05.03.2026 17:49 ๐Ÿ‘ 36 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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First whole-brain recording of social sound processing in a vertebrate. Surprises start in the hindbrain; thalamus gates conspecific calls; male and female brains diverge downstream. Work by @joerghenninger.bsky.social, @mh123.bsky.social sky.social and team. www.biorxiv.org/content/10.6...

05.03.2026 09:47 ๐Ÿ‘ 113 ๐Ÿ” 44 ๐Ÿ’ฌ 6 ๐Ÿ“Œ 4
Circuits, Dynamics, and Computation in Social Behavior, COSYNE 2026 COSYNE 2026 Workshop: Circuits, Dynamics, and Computation in Social Behavior

Psyched to announce our COSYNE workshop on social behaviors (Mar 17th, Cascais). We have a stellar lineup of speakers on topics from animal cooperation and aggression to the social dynamics of LLM agents.

Co-organized with Libby Zhang (Allen Institute + UW).
cosyne-social-behavior.github.io

06.03.2026 01:22 ๐Ÿ‘ 24 ๐Ÿ” 6 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0
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Going to #COSYNE2026? Don't miss our tutorial on our open neural dynamics data resources.

๐Ÿ—“๏ธ March 12, 9:15-10:15am
๐Ÿง‘โ€๐Ÿซ Presented by @sejdevries.bsky.social
๐Ÿ”— More info: https://www.cosyne.org/tutorials

@cosynemeeting.bsky.social

02.03.2026 23:08 ๐Ÿ‘ 11 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

This paper has now been published in PRX Life! journals.aps.org/prxlife/abst...

In this work I developed a scaling theory for spiking neural populations using a renormalization group approach -- the 1st, to my knowledge, applied to models of spiking neurons. See the thread for a brief summary.

10.10.2025 19:30 ๐Ÿ‘ 12 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Biological Laboratory | LEGOยฎ Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publโ€ฆ

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. ๐Ÿค—
beta.ideas.lego.com/product-idea...

16.10.2025 08:07 ๐Ÿ‘ 221 ๐Ÿ” 131 ๐Ÿ’ฌ 8 ๐Ÿ“Œ 12

The deadline to apply for the Brain Prize Cajal summer course in Computational Neuroscience has been extended to March 9! Weโ€™re excited for you to join us in sunny Lisbon! Please do not hesitate to send in an application and learn about computational neuroscience! @gjorjulijana.bsky.social

27.02.2026 19:05 ๐Ÿ‘ 15 ๐Ÿ” 11 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
An array of 9 purple discs on a blue background. Figure from Hinnerk Schulz-Hildebrandt.

An array of 9 purple discs on a blue background. Figure from Hinnerk Schulz-Hildebrandt.

A nice shift in perceived colour between central and peripheral vision. The fixated disc looks purple while the others look blue.

The effect presumably comes from the absence of S-cones in the fovea.

From Hinnerk Schulz-Hildebrandt:
arxiv.org/pdf/2509.115...

24.09.2025 10:16 ๐Ÿ‘ 770 ๐Ÿ” 296 ๐Ÿ’ฌ 33 ๐Ÿ“Œ 53
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The thing you have to understand about the 80s is that the Harlem Globetrotters could show up in anything at any time and nobody would bat an eye.

27.02.2026 22:40 ๐Ÿ‘ 536 ๐Ÿ” 101 ๐Ÿ’ฌ 22 ๐Ÿ“Œ 6

We need more <gestures broadly> tokens in our training sets.

27.02.2026 00:47 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Yes! Beautiful new work from a dream team!

26.02.2026 23:55 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Compact deep neural network models of the visual cortex Nature - Parsimonious deep neural network models can be used for prediction of visual neuron responses.

DNN models of the brain are getting bigger. Are we replacing one complicated system in vivo with another in silico?

In new work, we seek the *smallest* DNN models of visual cortex, balancing prediction with parsimony.

It turns out these compact models are surprisingly small!

rdcu.be/e5H8G

26.02.2026 22:32 ๐Ÿ‘ 109 ๐Ÿ” 38 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 3

Mostly, I think we undervalue the importance of *trying more ideas faster*.

26.02.2026 21:19 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

I am not here with a policy recommendation, but I think a misguided framing of studies as confirmatory and not exploratory (mostly for publication reasons) has resulted in a mandate for meta-science artifacts that presume every result needs to live forever. 3/n

26.02.2026 21:19 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

I value code sharing, data sharing (especially as a computationalist!), and reproducible workflows, but we have to be honest that these are taxes on our time, and the primary benefit is from the small number of high-impact studies that will be returned to over and over again. 2/n

26.02.2026 21:19 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

It's also worth saying that this is one of the hardest lessons I learned as a new PI: Maintenance is real! Projects are easy to start and hard to hand off. Technology that changes fast accelerates obsolescence. I think there's real value in trying ideas, letting some fail, and moving on. 1/n

26.02.2026 21:19 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

True, but even with well done software, dependency changes, as well as shifts in CI infrastructure, docs builds, and the rest really do add up. I bet most scientific packages have a shelf life of no more than two years of โ€œjust worksโ€ if not maintained. But C and FORTRAN from the 80s still compile!

26.02.2026 21:04 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The age and experience discrepancy between (mostly junior) scicomm folks and (more senior) PIs explains a lot of this. Seeing how quickly projects rot when lab members leave disincentives any product that requires continual maintenance. Same goes double for software.

26.02.2026 17:49 ๐Ÿ‘ 7 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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The Journal of Neuroscience: 46 (8)

Very excited to share a Special Collection at the Journal of Neuroscience (@sfnjournals.bsky.social) - Central Questions for Social Neuroscience Research. This issue includes some of the latest perspectives on social neuroscience research. Please check it out!๐Ÿ‘‡

www.jneurosci.org/content/46/8

25.02.2026 21:52 ๐Ÿ‘ 27 ๐Ÿ” 16 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

After several years of work, my lab is starting to put out our first papers on learning in a unicellular organism (Stentor coeruleus).

Here we show evidence for a form of associative learning in Stentor:
www.biorxiv.org/content/10.6...

26.02.2026 11:39 ๐Ÿ‘ 176 ๐Ÿ” 57 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 7

This study is super cool (connecting ecology and perception), that suggest some aspects of animal's perception (temporal precision) is shaped by their environment (which somehow resonates w our proposal on internal foraging perspectives on perceptual selection www.sciencedirect.com/science/arti...)

24.02.2026 13:51 ๐Ÿ‘ 28 ๐Ÿ” 10 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

Come be our colleague! The Center for Neural Science at NYU is accepting applications at the Assistant Professor level in computational neuroscience and/or neural engineering apply.interfolio.com/182074

25.02.2026 14:24 ๐Ÿ‘ 18 ๐Ÿ” 13 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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my local park is full of hundreds of snow sculptures and someone has been adding museum labels

24.02.2026 19:42 ๐Ÿ‘ 8144 ๐Ÿ” 2119 ๐Ÿ’ฌ 97 ๐Ÿ“Œ 265
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learningfromscratch march 16th, workshop day 1 @ cosyne 2026

Excited to be co-organising a #cosyne2026 workshop with Alison Comrie on 'algorithms for learning from scratch'! With a great line-up of speakers, we'll be tackling the question of what processes enable naive biological & artificial agents to adapt to new situations. Info here: tinyurl.com/4u8enf7k

24.02.2026 18:33 ๐Ÿ‘ 44 ๐Ÿ” 16 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

NYU's Center for Neural Science is seeking a faculty candidate that would be jointly appointed with our Tandon School of Engineering. We are looking for post-doc applicants with neuroengineering or computational backgrounds.

apply.interfolio.com/182074

24.02.2026 14:25 ๐Ÿ‘ 32 ๐Ÿ” 29 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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OpenAI Furious DeepSeek Might Have Stolen All the Data OpenAI Stole From Us OpenAI shocked that an AI company would train on someone else's data without permission or compensation.

Well, Steve [Jobs]โ€ฆ I think itโ€™s more like we both had this rich neighbour named Xerox and I broke into his house to steal the TV set and found out that you had already stolen it.
โ€” Bill Gates

24.02.2026 13:49 ๐Ÿ‘ 6 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Joe Gall was a very prominent cell biologist, and also famous for being a mentor to many female PhD students who went on to have very successful careers
this little anecdote really says it all
pmc.ncbi.nlm.nih.gov/articles/PMC...

23.02.2026 20:42 ๐Ÿ‘ 23 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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a black and white dog is sitting on a couch with its tongue sticking out . ALT: a black and white dog is sitting on a couch with its tongue sticking out .

๐Ÿ‘๏ธThe retina โ€” strikingly conserved across vertebrates, but an oddity among bilaterians!

So how did it evolve?

With @mikebok.bsky.social, @neurofishh.bsky.social and @denilsson.bsky.social, we argue that retinal complexity may ๐‘๐‘Ÿ๐‘’๐‘‘๐‘Ž๐‘ก๐‘’ ๐‘กโ„Ž๐‘’ ๐‘’๐‘ฆ๐‘’ ๐‘–๐‘ก๐‘ ๐‘’๐‘™๐‘“.

www.biorxiv.org/content/10.1...
1/n

12.09.2025 12:58 ๐Ÿ‘ 62 ๐Ÿ” 26 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 4
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New lab paper in #ScienceAdvances: we identify a modality-common selective-attention signal in noncholinergic #BasalForebrain (BF) โ€œburstingโ€ neurons, distinct from the modality-specific attention signals typically described in corticothalamic circuits. 1/n
www.science.org/doi/full/10....

20.02.2026 19:59 ๐Ÿ‘ 27 ๐Ÿ” 10 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1