Paul Glasziou

Yes - and to allow trials of early detection and treatment; so both screen and monitor *within* a clinical trial.

An Australian community jury to consider case‐finding for dementia: Differences between informed community preferences and general practice guidelines Case‐finding for dementia is practised by general practitioners (GPs) in Australia but without an awareness of community preferences. We explored the values and preferences of informed community members around case‐finding for dementia in Australian ...

Disappointing work from UKRI. And then even if it did help early diagnosis, our community jury didn’t want that if there was no effective early treatment - pmc.ncbi.nlm.nih.gov/articles/PMC...

NEW ANALYSIS: UK emissions fell 2.4% in 2025 as coal fell to a 400-year low. Incredibly, we used less coal last year than than in 1600, when Queen Elizabeth I was on the throne and Shakespeare was writing Hamlet.

All the details in our article: www.carbonbrief.org/...

Remembering the frequent comments from a couple of years back that there was no point in the US/Canada/Australia etc doing anything to decarbonise because what about China.

Well, indeed, what about China?

More is not always better.

This patient clearly explains why and how patients can/should say “hey, could I take fewer medications?”

Sometimes a prescriber just needs a nudge to reconsider how adding more and more pills is not the only answer to help people feel well again.

Reminds me of my 4th year med school physician tutor who wanted to start a Department of AntiPharmacology - which he described as teaching the art of curing people by taking them off their medications ;-)

Your Monthly Dose of Good News | February YouTube video by Good News

News depressing? Try a Good News break about the large biodiversity corridor in DRC, AI detection of whales (collision prevention); Brazil ends Mum2Bub HIV transmission; cheaper battery storage; China’s offshore solar, and more youtu.be/NyTP_oaZyks?...

The rate of change of renewables in China is accelerating. Solar has passed wind in generation. Fossil fuel generation is decreasing. Renewables will pass fossil fuels by the early 2030's or sooner. 🧪🔌💡☀️💨💧🔋

Netflix Backs Out of Bid for Warner Bros., Paving Way for an Ellison Takeover

The richest man owns X.

The second and third richest men control Google.

The fourth richest man owns Facebook, Instagram, and WhatsApp.

The fifth richest man owns The Washington Post.

And now the sixth richest could soon take over both Paramount and Warner Bros.

See the problem here?

We’ve had that feature for a few years. E.g. my Uni says “[CAUTION: External Sender]” about email from PLOS Medicine. Of course, no journal has a high enough IF to escape this warning ;-)

Australia’s most costly anti-climate policy hits taxpayers for $30m a day as calls mount to wind back fuel tax credits | Adam Morton The government will hand over $10.8bn this financial year under the scheme that makes it cheaper for miners and other industries to use diesel and petrol

Australia's most generous fossil fuel subsidy will pour another $11 billion of taxpayer money into the pockets of polluters this year, including coal and gas companies.

Oversight of Research Outputs by Public Organisations as a Threat to Research Integrity: A Personal Account from Australia - Journal of Academic Ethics Research governance processes in Australian public organisations raise significant concerns for research integrity, particularly regarding the pre-dissemination review and editing of research outputs....

Join ReproducibiliTea Melbourne journal club this Thursday 4pm AEDT, to discuss "Oversight of Research Outputs by Public Organisations as a Threat to Research Integrity” by C. Brandenburg & @aidybarnett.bsky.social

Zoom: uni-sydney.zoom.us/j/83909186903
#ResearchIntegrity @reproducibilitea.org

142,000 participants!
The largest randomized trial of a multi-cancer early detection (MCED) test failed its primary endpoint
genomeweb.com/cancer/grail...
Had the enrollment been risk-based instead of age 50, it would likely have been very positive.

In standard scientific reports in psych 96% of first mentioned main hypotheses are supported. In Registered Reports, this is 46%. The 96% is clearly biased (given true H1 rate and power). Lack of transparency means we do not know the true baserate.

journals.sagepub.com/doi/10.1177/...

A global map showing that most people don't talk about or hear about climate change regularly (except in Scandinavia - I believe this is the Greta Effect!). Source: Yale Program on Climate Change Communication.

A global map showing that most people are worried about climate change. Source: Yale Program on Climate Change Communication.

Most people are worried about climate change - but most don't hear or talk about regularly.

That's why I started my free newsletter Talking Climate. Every week I share good news, not so good news, and what people can do.

If you aren't a reader yet, see below. I have 6 different ways to subscribe!

Hans Rosling on why most of the world is better off than you think YouTube video by Channel 4 News

Great idea, and not just for crime. Most news stories could do with a Context Box to reduce misrepresentation & misunderstanding - with a dedication to Hans Rosling youtu.be/1vr6Q77lUHE?...

striking results!

Some lessons from my low back pain Background I know from personal experience that low back pain is a common and debilitating condition. Fortunately most acute episodes of low back pain resolve spontaneously within a few weeks or mo…

Some lessons about low back pain - here are some thoughts, experience, and evidence I'd accumulated following my microdiscectomy (for severe, prolonged sciatica) about 15 months ago. I hope this might help others & future research healthy-evidence.com/2026/01/30/s...

In 1922, insulin co-discoverer Frederick Banting refused to profit from the discovery and offered it to the world as a global public good.

Today, many people with diabetes still don't have access to affordable and quality treatment and care.

Electric vehicle sales overtake petrol in EU for first time Sales of fully electric cars surpassed those of petrol vehicles in the European Union for ‌the first time in December, even as policymakers proposed to loosen emissions regulations, data from the auto industry group ACEA showed on Tuesday.

Electric vehicle sales overtake petrol in EU for first time reut.rs/45wzENK

U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office A Science analysis reveals how many were fired, retired, or quit across 14 agencies

“At 14 research agencies Science examined in detail, departures outnumbered new hires last year by a ratio of 11 to one, resulting in a net loss of 4224 STEM Ph.D.s. “

www.science.org/content/arti...

United States Completes WHO Withdrawal WASHINGTON —  January 22, 2026 — The U.S. Department of Health and Human Services and the U.S. Department of State today announced the United States’ completion of its withdrawal from the World Health Organization (WHO) due to the organization's mishandling of the COVID-19 pandemic that arose out of Wuhan, China, its failure to adopt urgently needed reforms, and its inability to demonstrate independence from the inappropriate political influence of WHO member states.

The United States has officially withdrawn from the World Health Organization.

This is a shameful move that puts both Americans and people all over the world at greater risk from disease outbreaks, which require international collaboration to contain.

Will Australians continue to enjoy genuine choice at the next election? 🗳️ ⚖️

@simonahac.bsky.social weighs in on new laws that aim to entrench the major party duopoly at a time when Australians are asking for something different.

Learn more here → www.climate200.com.au/the-fair-ele...

Covers of the 2 leading science journals this week
@science.org and @nature.com
www.science.org/content/arti... www.nature.com/immersive/d4...

Here's the data:

Price of lithium-ion battery cells. Line chart showing representative estimates of battery cell prices in constant 2024 US dollars per kilowatt-hour across major cell chemistries from 1991 to 2024. Main insight: a steep fall from $9,210 per kWh in 1991 to about $78 per kWh in 2024, with most of the decline occurring through the 1990s and early 2000s before prices leveled off and gradually declined further. Y-axis labeled $0 to $10,000 with tick marks at roughly $2,000 intervals; x-axis covers years 1991 to 2024. Note: data are expressed in constant 2024 US$ per kilowatt-hour. Data source: Rupert Way (2026) based on Ziegler and Trancik (2021), BloombergNEF, and Avicenne Energy. Chart is licensed CC BY to Our World in Data.

📊 Data update: Track battery prices over the last three decades—

To transition towards low-carbon energy systems, we need *low-cost* energy storage. Lithium-ion batteries are the most commonly used.

Uruguay’s Renewable Charge: A Small Nation, A Big Lesson For The World Uruguay built a power grid that runs 99% on renewables—at half the cost of fossil fuels. Here’s how its bold energy overhaul became a global model.

“Uruguay did what most nations still call impossible: it built a power grid that runs almost entirely on renewables—at half the cost of fossil fuels. The physicist who led that transformation says the same playbook could work anywhere—if governments have the courage to change the rules.”

‘A silent majority’: MPs underestimate support for green policies, study reveals Exclusive: From solar subsidies to meat taxes, minority rightwing voices appear to drown out the consensus

A silent majority’: MPs underestimate support for green policies
From solar subsidies to meat taxes, minority rightwing voices appear to drown out the consensus
www.theguardian.com/environment/...

A half-planet-size gap in global governance is about to get plugged A new treaty offers hope of curbing the destruction of the oceans

Bit of good news - the Biodiversity Beyond National Jurisdiction agreement, which protects marine biodiversity in areas beyond national jurisdiction, comes into force on 17 January. It has 145 signatories (although the US has not signed up)
economist.com/internationa...

The rate of global sea level rise doubled during the past three decades - Communications Earth & Environment Global mean sea level rise amounted to 4.5 mm per year as a result of warming oceans and melting land ice, more than twice the rate of 2.1 mm/year observed at the start of satellite data in 1993, base...

The rate of global mean sea level rise has increased from ~2.1 mm/year in 1993 to ~4.5 mm/year in 2023. www.nature.com/articles/s43...