@drchristhorpe
Immunology/bioinformatics. Working towards higher fidelity models of MHC:peptide complexes/tools for immunologists/equity in data EMBL / Marie Skłodowska-Curie Actions ARISE fellow. https://orcid.org/0000-0002-4341-0320 https://www.histo.fyi/
🚨 Today is a big day for #BSI25... two deadlines!
📝 Late breaking abstract submissions close tonight
💳 Early bird registration also ends today
This is your last chance to present your work and secure your place at the best rate ➡️ https://bit.ly/3K6eFJz
Journalist Edward R. Murrow used his platform on CBS to criticize the witch hunts led by Senator Joseph McCarthy in the 1950s.
This is what real journalism should do — hold power to account, not capitulate to it.
A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Bloody hell, can't believe it's over 10 years.
ProteinDJ logo
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5)
doi.org/10.1101/2025.09.24.678028 #proteindesign
I’ll just leave this here as it’s awesome in every way and very needed.
Thank you Pulp and LCD Soundsystem. And of course Heaven 17
youtu.be/ydWHNkLtpcA
We’re recruiting a PhD Fellow in Computational Systems Immunology. Work on large-scale immune receptor datasets and develop computational models in close collaboration with experimental labs. Apply here: www.jobbnorge.no/en/available...
If you see this, post a bridge.
Labor productivity has more than doubled since the late 1960s. But workers’ compensation has barely budged.
Yes. The economy is rigged in favor of the wealthy.
We are hiring a PhD student 🎓
Work with me and Matthias Rüdt in our department on an exciting industry collaboration with Lonza combining high-throughput experiments and molecular modelling using AlphaFold and MolecularDynamics
📍 Sion, Valais, Switzerland
More info: www.jobup.ch/fr/emplois/d...
MolViewSpec: describe, share, and reproduce Mol* molecular scenes with a simple extension
I am disappointed in w3w.co/lager.lager....
I am also surprised/horrified at the news that Nuxx is over 30 years old.
Investing in people behind medical research fuels UK growth. A new report by Frontier Economics (funded by @amrc-uk.bsky.social & @wellcometrust.bsky.social) shows non-commercial clinical research adds £72.7bn to the economy. Driving innovation in prevention, diagnosis & treatment.
bit.ly/3KrW7nf
Whoah
Why did all of us never realise the greatest medical breakthroughs were this easy! Evidence from controlled studies with a sample size of millions falls away in thrall to a ‘feeling’ that it was the mothers’ ‘fault’ all along
For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?
You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...
Did you know his father was a tool maker?
Bubbly bubble is bubbly
Today I had to install Adobe InDesign, remind myself how to use it after almost 20 years and deliver files for printing in the space of 2 hours or the conference would not have had nice name badges. Underworld playlist helped.
I'm also on holiday, so I then went for a walk in this heavenly place.
GPU-accelerated MMseqs2 offers tremendous speedup for homology retrieval, protein structure prediction with ColabFold, and protein structure search with Foldseek. @martinsteinegger.bsky.social @milot.bsky.social @machine.learning.bio
www.nature.com/articles/s41...
Immunology affects everyone.
Join our new PPI Network to bring your voice into research & policy.
No science background needed – just passion & lived experience.
Applications close in 1 week.
🔗 https://bit.ly/3Jz7cT6
MLSB is coming to Copenhagen, DK 🎉
Submission is under the same portal, just simply indicate your location preference(s).
Really useful update from Bob Hawkins on Long Covid in England from the annual GP survey
bhawkins3.substack.com/p/long-covid...
iPhone SE (3rd Generation) is same for me.
Thoughtful piece by Abdel on social science genetics - I am definitely taken by “one person’s confounder is another person’s signal”. Also humble about dark histories here and his own perspective
This is a cool story that I've watched with great interest - making big steps in the field of de novo TCR generation! Great work @dkarthikey1.bsky.social / @benjamingvincent.bsky.social / @alexr.bsky.social et al
Very good piece from @dianecoyle1859.bsky.social on AI and future implications for the workplace at large, with context setting around the already existing digital divide. Thought provoking and insightful, I hope policymakers read it, re-read it and then have a really deep think/reset of policies
On to the management of your grant!
You need to keep track of your spending. Remember, you are expected to not just do what you promised, but also do what reviewers want, and create preliminary data for the next grant. This means you need to under-spend on the original deliverables.
Particulate air pollution drives Lewy Body Dementia via α-Synuclein @science.org @xiaobomao.bsky.social
www.science.org/doi/10.1126/...
