#WIMMinFocus
Not a T.rex but a pretentious gut tissue!
Spatial transcriptomics mapped 5,100 genes at subcellular resolution.
Captured by @vywien-lai.bsky.social, winner of the 2025 WIMM Image Competition ( #SciArt).
Proof that science doesn’t just uncover life’s mysteries — it gives you dinosaurs 🦕

It was fun to make this with our fabulous collaborators!

Iron and the immune system - Nature Reviews Immunology Iron is crucial for cellular metabolism, but its availability varies greatly within and between individuals and populations. This Review highlights how iron regulates innate and adaptive cellular and ...

2 new efforts: from Megan Teh on metabolism of CD8 Tcells in iron deficiency and why they love aspartate (+ @sarahdimeloe.bsky.social @lindavsinclair.bsky.social); & reviewing the strong influence of iron on immunity @joefrost.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...

Maternal iron deficiency causes male-to-female sex reversal in mouse embryos - Nature Iron-deficient conditions in pregnant mice can cause XY mouse embryos to develop female rather than male genitalia, revealing that iron metabolism has a role in determining male sex in mice.

Exciting and provocative paper for the iron field! www.nature.com/articles/s41...

I like Ricardo’s product placement

@rbeagrie.bsky.social thank you- but as you know (although modestly omitted) you made several absolutely crucial contributions and it could not have happened without you!

Ancient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis - Nature Communications Nprl3 controls erythroblast metabolism and is upregulated by α -globin enhancers sited within its introns. This arrangement couples metabolic and developmental control during erythropoiesis and may ex...

Wonderful to see this out, a big effort led by Alexandra Preston and fun for the lab to do something new (and very very old); plus it’s only slightly iron-related! 😳😱😀 www.nature.com/articles/s41...

Supercool Linda and team!

Drakesmith Group: Iron and Immunity We are investigating how iron and anaemia influence immunity and infectious diseases. Our research inspires treatments that control iron physiology to benefit the host at the expense of pathogens.

Hi Erik I'm a scientist at the MRC Weatherall Institute of Molecular Medicine, please add me to the science feed, thank you... www.imm.ox.ac.uk/research/res...

A pleasure to work with you Son!

The cover of the December issue is based on the article by Teh et al on iron utilization. The image illustrates the authors' goal to provide contemporary insights— symbolized by a laptop on a lectern showcasing iron trafficking—into enduring questions, represented by a gothic library adorned with iron-themed stained glass and ancient books.

The December issue of Trends in Endocrinology and Metabolism is online! With a Feature Review on iron utilization from cellular biochemistry to clinical pathology (on the cover), articles on vitamin D, hepatic gluconeogenesis, autophagy and lysosomal dysfunctions, hypoxia during pregnancy and more!

Why cells need iron: a compendium of iron utilisation Iron deficiency is globally prevalent, causing an array of developmental, haematological, immunological, neurological, and cardiometabolic impairments, and is associated with symptoms ranging from chr...

Ever wondered why our cells need iron? Check out the new Feature Review from the Drakesmith Lab in the latest issue of Trends in Endocrinology & Metabolism to learn more!🧪

Read the review: bit.ly/3CYA3NC